PMID: J Cell Biochem. 2019 Oct 14. Epub 2019 Oct 14. PMID: 31609017 Abstract Title: Therapeutic and biological activities of berberine: The involvement of Nrf2 signaling pathway. Abstract: Since the beginning of the 21st century, studies have focused on developing drugs from naturally occurring compounds. Berberine (Brb) as a plant-derived compound is of interest. It …
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High-dose berberine ameliorated cigarette smoke extract-induced airway inflammation in COPD mice.
PMID: Curr Med Sci. 2019 Oct ;39(5):748-753. Epub 2019 Oct 14. PMID: 31612392 Abstract Title: Berberine Attenuates Cigarette Smoke Extract-induced Airway Inflammation in Mice: Involvement of TGF-β1/Smads Signaling Pathway. Abstract: Although several studies confirmed that berberine may attenuate airway inflammation in mice with chronic obstructive pulmonary disease (COPD), its underlying mechanisms were not clear until …
Role of JAK2 in the pathogenesis of diabetic erectile dysfunction and an intervention with berberine.
PMID: J Sex Med. 2019 Sep 26. Epub 2019 Sep 26. PMID: 31564534 Abstract Title: Role of JAK2 in the Pathogenesis of Diabetic Erectile Dysfunction and an Intervention With Berberine. Abstract: BACKGROUND: Oxidative stress is a significant contributor to the poor treatment efficacy on erectile dysfunction induced by diabetes mellitus (DMED). Thus, understanding the mechanism …
Daily oral pomegranate consumption may lead to enhanced protection from ultraviolet photodamage.
PMID: Sci Rep. 2019 Oct 10 ;9(1):14528. Epub 2019 Oct 10. PMID: 31601842 Abstract Title: Pomegranate Juice and Extract Consumption Increases the Resistance to UVB-induced Erythema and Changes the Skin Microbiome in Healthy Women: a Randomized Controlled Trial. Abstract: In vitro and animal studies have demonstrated that topical application and oral consumption of pomegranate reduces …
[Video] Could you fail a drug test by taking CBD?
Cannabidiol, or CBD, is a non-psychoactive compound produced by the marijuana plant that seems to be everywhere these days. Maybe you’ve even been asked if you’d like it added to your morning cup of joe! Interestingly, the chemical structure of CBD is very similar to THC, which is the marijuana-derived compound responsible for getting …
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Ginkgo biloba extract improves brain uptake of ginsenosides by increasing blood-brain barrier permeability.
PMID: J Ethnopharmacol. 2020 Jan 10 ;246:112243. Epub 2019 Sep 18. PMID: 31541722 Abstract Title: Ginkgo biloba extract improves brain uptake of ginsenosides by increasing blood-brain barrier permeability via activating A1 adenosine receptor signaling pathway. Abstract: ETHNOPHARMACOLOGICAL RELEVANCE: Ginkgo biloba leaves and Panax ginseng are Chinese medicine commonly used in combination for cerebral disease.AIM OF …
The inhibitory effect of Ginkgo biloba exocarp extracts on the growth of B16 melanoma transplant tumor in mice is related to inhibiting angiogenesis.
PMID: Iran J Pharm Res. 2019 ;18(2):803-811. PMID: 31531063 Abstract Title: Anti-tumor Effect ofExocarp Extracts on B16 Melanoma Bearing Mice Involving P I3K/Akt/HIF-1α/VEGF Signaling Pathways. Abstract: The objective of this study is to investigate the anti-tumor effect ofexocarp extracts (GBEE) on B16 melanoma bearing mice and its related molecular mechanisms. The B16-F10 melanoma solid tumor …
Ginkgo biloba extract inhibits metastasis and in gastric cancer.
PMID: Med Sci Monit. 2019 Sep 11 ;25:6836-6845. Epub 2019 Sep 11. PMID: 31509521 Abstract Title: Ginkgo Biloba Extract Inhibits Metastasis and ERK/Nuclear Factor kappa B (NF-κB) Signaling Pathway in Gastric Cancer. Abstract: BACKGROUND Ginkgo biloba extract (EGb761), a standard extract of the Chinese traditional medicine Ginkgo biloba, plays an anti-tumor role in various cancers. …
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Hemp seed and evening primrose oils treatment can be used to ameliorate the demyelination of spinal cord.
PMID: Res Pharm Sci. 2019 Apr ;14(2):146-154. Epub 2019 Mar 8. PMID: 31620191 Abstract Title: Hemp seed/evening primrose oil affects expression of STAT3, IL-17, and FOXP3in experimental autoimmune encephalomyelitis. Abstract: T helper (Th)-17 mediate inflammation in both peripheral tissues and the central nervous system. Signal transducer and activator of transcription factor3 (STAT3) is required for …
Coumaroylaminobutanol glucopyranoside from hemp seed inhibits LPS-stimulated neuroinflammation in BV2 microglia by regulating NF-κB and Nrf-2 pathways.
PMID: ACS Omega. 2019 Oct 8 ;4(15):16517-16523. Epub 2019 Sep 26. PMID: 31616830 Abstract Title: CLG from Hemp Seed Inhibits LPS-Stimulated Neuroinflammation in BV2 Microglia by Regulating NF-κB and Nrf-2 Pathways. Abstract: The healthy benefits of hemp (L.) seed have often been attributed to its oils and proteins. Recent studies reveal that hemp seed phenylpropionamides …
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