PMID: Chem Biol Interact. 2019 Sep 1 ;310:108740. Epub 2019 Jul 6. PMID: 31288002 Abstract Title: Luteolin and 5-flurouracil act synergistically to induce cellular weapons in experimentally induced Solid Ehrlich Carcinoma: Realistic role of P53; a guardian fights in a cellular battle. Abstract: BACKGROUND: Solid Ehrlich Carcinoma (SEC) is an undifferentiated tumor used in tumor …
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Luteolin reduces adipose tissue macrophage inflammation and insulin resistance in postmenopausal obese mice.
PMID: J Nutr Biochem. 2019 Sep ;71:72-81. Epub 2019 Jun 20. PMID: 31302373 Abstract Title: Luteolin reduces adipose tissue macrophage inflammation and insulin resistance in postmenopausal obese mice. Abstract: Previously, we showed that loss of ovarian function in mice fed high-fat diet exacerbated insulin resistance and adipose tissue inflammation. In the current study, we tested …
PTP1B phosphatase as a novel target of oleuropein activity in MCF-7 breast cancer model.
PMID: Toxicol In Vitro. 2019 Aug 13 ;61:104624. Epub 2019 Aug 13. PMID: 31419504 Abstract Title: PTP1B phosphatase as a novel target of oleuropein activity in MCF-7 breast cancer model. Abstract: Phosphatase PTP1B has become a therapeutic target for the treatment of type 2-diabetes, whereas recent studies have revealed that PTP1B plays a pivotal role …
This data identify a novel pathway through which oleuropein exerts a proapoptotic effect in NSCLC.
PMID: Oxid Med Cell Longev. 2019 ;2019:8576961. Epub 2019 Jul 22. PMID: 31428230 Abstract Title: Oleuropein-Induced Apoptosis Is Mediated by Mitochondrial Glyoxalase 2 in NSCLC A549 Cells: A Mechanistic Inside and a Possible Novel Nonenzymatic Role for an Ancient Enzyme. Abstract: Oleuropein (OP) is a bioactive compound derived from plants of the genus Oleaceae exhibiting …
Green tea extract mouthwash has a promising effect in decreasing the count of salivary S. mutans and in the prevention of dental caries.
PMID: Int J Clin Pediatr Dent. 2019 Mar-Apr;12(2):133-138. PMID: 31571786 Abstract Title: Effect of Green Tea Extract Mouthwash on SalivaryCounts in a Group of Preschool Children: AnStudy. Abstract: Aim: This study was conducted to evaluate the effectiveness of green tea mouthwash on the salivary level ofin the preschool children.Materials and methods: In this randomized controlled …
Green tea extract catechins protect against NF-κB-mediated liver injury in nonalcoholic steatohepatitis.
PMID: Mol Nutr Food Res. 2019 Oct 1:e1900811. Epub 2019 Oct 1. PMID: 31574193 Abstract Title: Green Tea Extract Treatment in Obese Mice with Nonalcoholic Steatohepatitis Restores the Hepatic Metabolome in Association with Limiting Endotoxemia-TLR4-NFκB-Mediated Inflammation. Abstract: SCOPE: Catechin-rich green tea extract (GTE) alleviates nonalcoholic steatohepatitis (NASH) by lowering endotoxin-TLR4 (Toll-like receptor-4)-NFκB (nuclear factor kappa-B) …
Intake of concentrated green tea catechin preparations may confer a significant protective effect to carriers of early neoplastic lesions in the prostate.
PMID: Arch Ital Urol Androl. 2019 Oct 2 ;91(3). Epub 2019 Oct 2. PMID: 31577096 Abstract Title: Green tea catechins for chemoprevention of prostate cancer in patients with histologically-proven HG-PIN or ASAP. Concise review and meta-analysis. Abstract: A focused, single outcome meta-analysis on the protective role of extracts of green tea catechins against prostate cancer. …
Tea consumption is associated with a reduced risk of coronary heart disease in female but not male populations in Guangzhou.
PMID: Nutr Res Pract. 2019 Oct ;13(5):393-398. Epub 2019 Jul 26. PMID: 31583058 Abstract Title: Tea consumption is associated with a reduced risk of coronary heart disease in female but not male populations in Guangzhou, China. Abstract: BACKGROUND/OBJECTIVES: The association between tea consumption and risk of coronary heart disease (CHD) remains controversial. This study aimed …
The nitrergic neurotransmission contributes to the anxiolytic-like effect of Citrus sinensis essential oil in animal models.
PMID: Phytother Res. 2019 Apr ;33(4):901-909. Epub 2019 Feb 3. PMID: 30714232 Abstract Title: The nitrergic neurotransmission contributes to the anxiolytic-like effect of Citrus sinensis essential oil in animal models. Abstract: Citrus fragrances have been used in aromatherapy for the treatment of anxiety, and the essential oil of Citrus sinensis (sweet orange) has shown promising …
These results demonstrate that continuous Oligonol treatment attenuates Alzheimer disease-like pathology and cognitive impairment.
PMID: Nutr Neurosci. 2019 Oct 11:1-15. Epub 2019 Oct 11. PMID: 31603034 Abstract Title: Flavanol-rich lychee fruit extract substantially reduces progressive cognitive and molecular deficits in a triple-transgenic animal model of Alzheimer disease. Abstract: Effective treatment to prevent or arrest the advance of Alzheimer disease (AD) has yet to be discovered. We investigated whether Oligonol, …
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