Category Archives: Uncategorized

PMID:  Artif Cells Nanomed Biotechnol. 2019 Dec ;47(1):3265-3271. PMID: 31368817 Abstract Title:  Luteolin exhibits anti-breast cancer property through up-regulating miR-203. Abstract:  Luteolin is a representative of natural flavonoid that has anti-tumour properties. This study designed to check its impact on breast cancer and the underlying mechanisms. MDA-MB-453 and MCF-7 cells were administrated with luteolin and …

Continue reading “Luteolin exhibits anti-breast cancer property through up-regulating miR-203.”

PMID:  J Surg Res. 2019 Oct 10 ;246:213-223. Epub 2019 Oct 10. PMID: 31606511 Abstract Title:  Quercetin Promotes Diabetic Wound Healing via Switching Macrophages From M1 to M2 Polarization. Abstract:  BACKGROUND: For patients with diabetes mellitus, excessive and long-lasting inflammatory reactions at the wound site commonly lead to the delayed refractory wound healing. The polarization of …

Continue reading “Quercetin promotes diabetic wound healing via switching macrophages from M1 to M2 polarization.”

PMID:  Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2019 Oct ;27(5):1409-1415. PMID: 31607291 Abstract Title:  [Effect of Quercetin on Wnt/β-Catenin Signal Pathway of K562 and K562R Cells]. Abstract:  OBJECTIVE: To investigate the effect of Quercetin (Qu) on cell proliferation, apoptosis and cell cycle, as well as the expression changes of Wnt/β-catenin signaling pathway, apoptosis …

Continue reading “Quercetin can inhibit the proliferation K562 and K562R cells.”

PMID:  Life Sci. 2019 Oct 12:116933. Epub 2019 Oct 12. PMID: 31614146 Abstract Title:  Beyond its antioxidant properties: Quercetin targets multiple signalling pathways in hepatocellular carcinoma in rats. Abstract:  AIMS: Hepatocellular carcinoma (HCC) pathogenesis involves the interplay of multiple signalling pathways. Notch and Hedgehog (Hh) are two major developmental pathways that act in concert to …

Continue reading “Beyond its antioxidant properties: Quercetin targets multiple signalling pathways in hepatocellular carcinoma in rats.”

PMID:  Life Sci. 2019 Oct 14:116956. Epub 2019 Oct 14. PMID: 31622607 Abstract Title:  Rheumatoid arthritis induces enteric neurodegeneration and jejunal inflammation, and quercetin promotes neuroprotective and anti-inflammatory actions. Abstract:  AIMS: The aim of our study was to study the pathological mechanisms induced by the rheumatoid arthritis (RA) on the Enteric Nervous System (ENS).MAIN METHODS: …

Continue reading “Quercetin is an important antioxidant supplement in preventing the progression of the rheumatoid arthritis severity.”

PMID:  Food Chem. 2019 Dec 15 ;301:125295. Epub 2019 Jul 30. PMID: 31387038 Abstract Title:  The effects of organic and conventional farm management and harvest time on the polyphenol content in different raspberry cultivars. Abstract:  Raspberry fruits are a perfect source of polyphenols, including flavonols, anthocyanins. Some experiments have indicated that organic fruits contain more …

Continue reading “The organic samples contained significantly more dry matter, phenolic acid and flavonoids.”

PMID:  Biochem Biophys Res Commun. 2019 Oct 1 ;517(4):617-622. Epub 2019 Aug 3. PMID: 31383362 Abstract Title:  Regulation of apoptosis and autophagy by luteolin in human hepatocellular cancer Hep3B cells. Abstract:  In several cancer cells, luteolin (3',4',5,7-tetrahydroxyflavone) exerts anticancer effects by upregulation of oxidative stress and endoplasmic reticulum (ER) stress, which are shown to activate …

Continue reading “Regulation of apoptosis and autophagy by luteolin in human hepatocellular cancer Hep3B cells.”

PMID:  EXCLI J. 2019 ;18:750-763. Epub 2019 Sep 2. PMID: 31611756 Abstract Title:  Differential effects of luteolin and its glycosides on invasion and apoptosis in MDA-MB-231 triple-negative breast cancer cells. Abstract:  Luteolin is known to have anticancer activity in various cancers. Recent studies have shown that luteolin glycosides, such as luteolin-8–β-fucopyranoside, 7-methoxy-luteolin-8-C-β-(6- deoxyxylopyranos-3-uloside) and luteolin-8-C-β-d-glucopyranoside, …

Continue reading “Differential effects of luteolin and its glycosides on invasion and apoptosis in MDA-MB-231 triple-negative breast cancer cells.”

PMID:  Pestic Biochem Physiol. 2019 Sep ;159:163-172. Epub 2019 Jun 24. PMID: 31400778 Abstract Title:  Apigenin attenuates edifenphos-induced toxicity by modulating ROS-mediated oxidative stress, mitochondrial dysfunction and caspase signal pathway in rat liver and kidney. Abstract:  Edifenphos (EDF) (O-ethyl-S, S-diphenyldithiophosphate) is an organophosphate pesticide that is extensively used as a fungicide in agricultural rice fields. …

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PMID:  Food Chem Toxicol. 2019 Nov ;133:110780. Epub 2019 Aug 23. PMID: 31449894 Abstract Title:  Dietary Apigenin promotes lipid catabolism, thermogenesis, and browning in adipose tissues of HFD-Fed mice. Abstract:  Dietary Apigenin (AP), a natural flavonoid from plants, could alleviate high-fat diet (HFD) induced obesity and its complication. Nonetheless, the direct correlation between dietary AP …

Continue reading “Apigenin could be explored as a new dietary strategy to combat obesity and related insulin resistance.”