Berberine clears Aβ deposit and consequently ameliorates spatial learning memory impairment.

PMID:  Front Pharmacol. 2019 ;10:1003. Epub 2019 Sep 6. PMID: 31551793 Abstract Title:  Berberine Ameliorates Spatial Learning Memory Impairment and Modulates Cholinergic Anti-Inflammatory Pathway in Diabetic Rats. Abstract:  Cognitive impairment caused by diabetes has been recognized. Berberine is well known for its resistance to peripheral lesions, but it is rarely used for the treatment of …

Astaxanthin ameliorates the lipopolysaccharides-induced subfertility.

PMID:  Dose Response. 2019 Jul-Sep;17(3):1559325819878537. Epub 2019 Sep 25. PMID: 31598118 Abstract Title:  Astaxanthin Ameliorates the Lipopolysaccharides-Induced Subfertility in Mouse via Nrf2/HO-1 Antioxidant Pathway. Abstract:  The endotoxin lipopolysaccharide (LPS) exists in human semen, which is associated with reduced sperm quality. Studying the LPS-impaired spermatozoa motility and viability, and discovering effective therapeutic treatments have crucial importance. …

Effect of berberine on the HPA-axis pathway and skeletal muscle GLUT4 in type 2 diabetes mellitus rats.

PMID:  Diabetes Metab Syndr Obes. 2019 ;12:1717-1725. Epub 2019 Sep 3. PMID: 31564939 Abstract Title:  Effect of berberine on the HPA-axis pathway and skeletal muscle GLUT4 in type 2 diabetes mellitus rats. Abstract:  Purpose: Activation of the hypothalamus-pituitary-adrenal (HPA) axis pathway is closely related to insulin resistance (IR), glucose, and lipid metabolism disorders in type …

Berberine was found to be an effective agent in the attenuation of diclofenac-induced acute kidney injury.

PMID:  J Pak Med Assoc. 2019 Aug ;69(Suppl 3)(8):S83-S87. PMID: 31603884 Abstract Title:  Reno-protective effect of berberine. Abstract:  Objective: To assess the reno-protective effect of berberine on diclofenac-induced acute kidney injury in rats.Methods: The experimental study was conducted at the College of Medicine, Mustansiriya University, Baghdad, Iraq, from January to March 2018, and comprised Sprague …

Red ginger oil has antihyperalgesia activity in mice with chronic pain and could be developed further to be antihyperalgesia.

PMID:  Pak J Pharm Sci. 2019 Jul ;32(4):1663-1669. PMID: 31608888 Abstract Title:  Antihyperalgesia potency of Zingiber officinale var. Rubrum in inflammatory and neuropathy-induced chronic pain condition in mice. Abstract:  Chronic inflammation and neuropathic pain are classified into chronic pain. Until now there are so many drugs that have been used for chronic pain but the …

Zingiber officinale extract and omega-3 fatty acids ameliorate endoplasmic reticulum stress in a nonalcoholic fatty liver rat model.

PMID:  J Food Biochem. 2019 Oct 14:e13076. Epub 2019 Oct 14. PMID: 31608477 Abstract Title:  Zingiber officinale extract and omega-3 fatty acids ameliorate endoplasmic reticulum stress in a nonalcoholic fatty liver rat model. Abstract:  Endoplasmic reticulum (ER) stress was reported to play a major role in non-alcoholic fatty liver disease (NAFLD) induction and progression. Here, …

Omega-3 polyunsaturated fatty acids prevent Toxoplasma gondii infection.

PMID:  Nutrients. 2019 Sep 6 ;11(9). Epub 2019 Sep 6. PMID: 31500218 Abstract Title:  Omega-3 Polyunsaturated Fatty Acids PreventInfection by Inducing Autophagy via AMPK Activation. Abstract:  Omega-3 polyunsaturated fatty acids (ω3-PUFAs) have potential protective activity in a variety of infectious diseases, but their actions and underlying mechanisms ininfection remain poorly understood. Here, we report that …

Results of this meta-analytic study suggested that T. gondii can be considered a risk factor for the development of Alzheimer’s disease.

PMID:  Microb Pathog. 2019 Sep 16 ;137:103751. Epub 2019 Sep 16. PMID: 31536800 Abstract Title:  Is Toxoplasma gondii a potential risk factor for Alzheimer's disease? A systematic review and meta-analysis. Abstract:  Toxoplasmosis is a major public health concern due to neurotropic nature and role in the development of mental and behavioral disorders. Alzheimer's disease (AD) …

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