Kinetics of acetylcholinesterase inhibition by hemp seed protein-derived peptides.

PMID:  J Food Biochem. 2019 Jul ;43(7):e12897. Epub 2019 May 15. PMID: 31353736 Abstract Title:  Kinetics of acetylcholinesterase inhibition by hemp seed protein-derived peptides. Abstract:  The aim of this work was to enhance the acetylcholinesterase (AChE)-inhibitory activity of a pepsin-produced hemp seed protein hydrolysates (HPH) through reverse-phase HPLC separation followed by identification of peptide sequences …

Cannabis use by inflammatory bowel disease patients can induce clinical improvement and is associated with reduced use of medication and slight weight gain.

PMID:  Eur J Gastroenterol Hepatol. 2019 Nov ;31(11):1376-1381. PMID: 31567639 Abstract Title:  Medical cannabis for inflammatory bowel disease: real-life experience of mode of consumption and assessment of side-effects. Abstract:  OBJECTIVE: Use of medical cannabis for improving symptoms of inflammatory bowel disease is increasing. However, reports on long-term outcomes are lacking. This prospective, observational study assessed …

Acute effects of lysergic acid diethylamide (LSD) on resting brain function.

PMID:  Swiss Med Wkly. 2019 Sep 23 ;149:w20124. Epub 2019 Sep 30. PMID: 31568558 Abstract Title:  Acute effects of lysergic acid diethylamide (LSD) on resting brain function. Abstract:  Lysergic acid diethylamide (LSD) is a potent hallucinogenic substance that was extensively investigated by psychiatrists during the 1950s and 1960s. Researchers were interested in the unique effects …

Antiproliferative and antioxidant effect of polar hemp extracts in human colorectal cell lines.

PMID:  Int J Food Sci Nutr. 2019 Sep 23:1-14. Epub 2019 Sep 23. PMID: 31544542 Abstract Title:  Antiproliferative and antioxidant effect of polar hemp extracts (L., Fedora.) in human colorectal cell lines. Abstract:  Total phenolic content and antioxidant activity of polar extracts of edible resources from Fedora hemp cultivar (L.), namely seed, flour and oil, …

Neuroprotective protein hydrolysates from hemp seeds.

PMID:  Food Funct. 2019 Oct 2. Epub 2019 Oct 2. PMID: 31576391 Abstract Title:  Neuroprotective protein hydrolysates from hemp (Cannabis sativa L.) seeds. Abstract:  Hemp (Cannabis sativa L.) seeds are well known for their potential use as a source of nutrients, fiber, and bioactive compounds. A hemp protein isolate, prepared from defatted hemp flour, was …

Antinociceptive effects of Salvia divinorum and bioactive salvinorins in experimental pain models.

PMID:  J Ethnopharmacol. 2019 Oct 5:112276. Epub 2019 Oct 5. PMID: 31593812 Abstract Title:  Antinociceptive effects of Salvia divinorum and bioactive salvinorins in experimental pain models in mice. Abstract:  ETHNOPHARMACOLOGICAL RELEVANCE: Salvia divinorum Epling&Játiva is a Mexican plant used not only in rituals but also in traditional medicine for pain relief. One of the most …

Proton pump inhibitor use increases mortality and hepatic decompensation in liver cirrhosis.

PMID:  World J Gastroenterol. 2019 Sep 7 ;25(33):4933-4944. PMID: 31543684 Abstract Title:  Proton pump inhibitor use increases mortality and hepatic decompensation in liver cirrhosis. Abstract:  BACKGROUND: Proton pump inhibitors (PPIs) are widely prescribed, often without clear indications. There are conflicting data on its association with mortality risk and hepatic decompensation in cirrhotic patients. Furthermore, PPI …

Cannabidiol Is a novel modulator of bacterial membrane vesicles.

PMID:  Front Cell Infect Microbiol. 2019 ;9:324. Epub 2019 Sep 10. PMID: 31552202 Abstract Title:  Cannabidiol Is a Novel Modulator of Bacterial Membrane Vesicles. Abstract:  Membrane vesicles (MVs) released from bacteria participate in cell communication and host-pathogen interactions. Roles for MVs in antibiotic resistance are gaining increased attention and in this study we investigated if …

Enhancing breast cancer treatment using a combination of cannabidiol and gold nanoparticles for photodynamic therapy.

PMID:  Int J Mol Sci. 2019 Sep 26 ;20(19). Epub 2019 Sep 26. PMID: 31561450 Abstract Title:  Enhancing Breast Cancer Treatment Using a Combination of Cannabidiol and Gold Nanoparticles for Photodynamic Therapy. Abstract:  Indisputably, cancer is a global crisis that requires immediate intervention. Despite the use of conventional treatments over the past decades, it is …

The evaluation of Cannabidiol’s effect on the immunotherapy of Burkitt lymphoma.

PMID:  Biochem Biophys Res Commun. 2019 Oct 3. Epub 2019 Oct 3. PMID: 31587870 Abstract Title:  The evaluation of Cannabidiol's effect on the immunotherapy of Burkitt lymphoma. Abstract:  AIM: AF1q has a precise oncogenic function. The purpose of this study is to investigate whether CBD has an effect on the AF1q/ICAM-1 regulatory axis in Burkitt's …

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