PMID: Prog Mol Biol Transl Sci. 2019 ;167:25-75. Epub 2019 Aug 28. PMID: 31601406 Abstract Title: Effects of cannabidiol (CBD) in neuropsychiatric disorders: A review of pre-clinical and clinical findings. Abstract: Cannabis sativa (cannabis) is one of the oldest plants cultivated by men. Cannabidiol (CBD) is the major non-psychomimetic compound derived from cannabis. It has …
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Puerarin protects pulmonary arteries from hypoxic injury.
PMID: Pharmacol Rep. 2019 May 7 ;71(5):855-861. Epub 2019 May 7. PMID: 31408784 Abstract Title: Puerarin protects pulmonary arteries from hypoxic injury through the BMPRII and PPARγ signaling pathways in endothelial cells. Abstract: BACKGROUND: Recent evidence indicates that Puerarin has a protective effect on pulmonary arteries. In the present study, we aimed to investigate whether …
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Tanshinone IIA attenuates demyelination and promotes remyelination in A. cantonensis-infected BALB/c mice.
PMID: Int J Biol Sci. 2019 ;15(10):2211-2223. Epub 2019 Aug 19. PMID: 31592236 Abstract Title: Tanshinone IIA attenuates demyelination and promotes remyelination in-infected BALB/c mice. Abstract: BACKGROUND: infection can cause demyelination in the central nervous system, and there is no effective treatment.METHODS: We used dexamethasone, Tanshinone IIA (TSIIA) and Cryptotanshinone(Two traditional Chinese medicine monomers) in …
Puerarin inhibits apoptosis and inflammation in myocardial cells via PPARα expression in rats with chronic heart failure.
PMID: Exp Ther Med. 2019 Nov ;18(5):3347-3356. Epub 2019 Sep 6. PMID: 31602208 Abstract Title: Puerarin inhibits apoptosis and inflammation in myocardial cells via PPARα expression in rats with chronic heart failure. Abstract: Chronic heart failure affects myocardial energy metabolism and cardiac function. Puerarin has been reported to improve cardiac function through regulation of energy …
Cloudy apple juice potentiates hepatoprotection during experimental liver injury.
PMID: Int J Biol Macromol. 2019 Aug 21 ;140:1006-1017. Epub 2019 Aug 21. PMID: 31445146 Abstract Title: COX-2/iNOS regulation during experimental hepatic injury and its mitigation by cloudy apple juice. Abstract: A number of enzymes and transcription factors have been correlated with disease etiology. In this study, involvement of cyclooxygenase-2 and inducible-nitric oxide synthase is …
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These results provide a new mechanism by which procyanidins exert their beneficial anti-inflammatory effects.
PMID: Front Immunol. 2019 ;10:1895. Epub 2019 Aug 7. PMID: 31440258 Abstract Title: Procyanidin B2 Activates PPARγ to Induce M2 Polarization in Mouse Macrophages. Abstract: Procyanidins, a subclass of flavonoids found in commonly consumed foods, possess potential anti-inflammatory activity. Manipulation of M1/M2 macrophage homeostasis is an effective strategy for the treatment of metabolic inflammatory diseases. …
These results provide evidence for the cardioprotective action of grape seed procyanidin B2 against asporin injury.
PMID: Cell Biol Int. 2019 Sep 9. Epub 2019 Sep 9. PMID: 31498521 Abstract Title: The protective effects of grape seed procyanidin B2 against asporin mediates glycated low-density lipoprotein induced-cardiomyocyte apoptosis and fibrosis. Abstract: The progression of diabetic cardiomyopathy is related to cardiomyocyte dysfunction and apoptosis. Our previous studies showed that asporin (ASPN) was significantly increased …
Procyanidin B2 suppressed lipopolysaccharide-induced inflammation and apoptosis in human alveolar epithelial cells and lung fibroblasts.
PMID: J Interferon Cytokine Res. 2019 Oct 11. Epub 2019 Oct 11. PMID: 31603717 Abstract Title: Procyanidin B2 Suppresses Lipopolysaccharides-Induced Inflammation and Apoptosis in Human Type II Alveolar Epithelial Cells and Lung Fibroblasts. Abstract: Acute lung injury (ALI) is characterized by acute lung inflammation and apoptosis of alveolar epithelial cells (AECs) with a high morbidity …
A 5-week Seminar on the biopsychosocial-spiritual model of self-care improves anxiety, self-compassion, mindfulness, depression, and stress.
PMID: Int J Yoga Therap. 2019 May 30. Epub 2019 May 30. PMID: 31145028 Abstract Title: A 5-Week Seminar on the Biopsychosocial-Spiritual Model of Self-Care Improves Anxiety, Self-Compassion, Mindfulness, Depression, and Stress in Graduate Healthcare Students. Abstract: Graduate healthcare students can experience stress that affects their ability to perform academically and clinically, decreases empathy, and …
Short mindfulness meditation program might be a promising approach for individuals with spasticity following stroke.
PMID: J Evid Based Integr Med. 2019 Jan-Dec;24:2515690X19855941. PMID: 31215234 Abstract Title: Mindfulness Meditation Effects on Poststroke Spasticity: A Feasibility Study. Abstract: This study examined the feasibility of an adapted 2-week mindfulness meditation protocol for chronic stroke survivors. In addition, preliminary effects of this adapted intervention on spasticity and quality of life in individuals after …
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