Category Archives: Uncategorized

PMID:  Biosci Biotechnol Biochem. 2003 Feb ;67(2):445-7. PMID: 12729019 Abstract Title:  6-hydroxyflavonoids as alpha-glucosidase inhibitors from marjoram (Origanum majorana) leaves. Abstract:  A methanol extract of marjoram leaves strongly inhibited rat intestinal alpha-glucosidase. Five 6-hydroxyflavonoids, 6-hydroxyapigenin (scutellarein; IC50 for sucrose hydrolysis by rat intestinal alpha-glucosidase, 12 microM), 6-hydroxyapigenin-7-O-beta-D-glucopyranoside (>500 microM), 6-hydroxyluteolin-7-O-beta-D-glucopyranoside (300 microM), 6-hydroxyapigenin-7-O-(6-O-feruloyl)-beta-D-glucopyranoside (>500 microM), …

Continue reading “6-hydroxyflavonoids as alpha-glucosidase inhibitors from marjoram leaves.”

PMID:  Leuk Res. 2010 Aug ;34(8):1052-6. Epub 2009 Oct 23. PMID: 19853912 Abstract Title:  The apoptotic and anti-proliferative activity of Origanum majorana extracts on human leukemic cell line. Abstract:  Scientists are constantly searching for phytochemicals and compounds with anti-cancer and antioxidant activity. In this study, the anti-proliferative activity of plant extracts from Origanum majorana (marjoram) …

Continue reading “The apoptotic and anti-proliferative activity of Origanum majorana extracts on human leukemic cell line.”

PMID:  Cardiovasc Toxicol. 2013 Jun ;13(2):100-9. PMID: 23054890 Abstract Title:  Preventive effects of Egyptian sweet marjoram (Origanum majorana L.) leaves on haematological changes and cardiotoxicity in isoproterenol-treated albino rats. Abstract:  We made an attempt to evaluate/compare the cardioprotective activity of two different doses (50 and 100 mg/kg body weight, given orally for 30 consecutive days) …

Continue reading “Egyptian marjoram could protet against isoproterenol induced cardiotoxicity.”

n/a PMID:  PLoS One. 2013 ;8(2):e56649. Epub 2013 Feb 22. PMID: 23451065 Abstract Title:  Mitotic arrest and apoptosis in breast cancer cells induced by Origanum majorana extract: upregulation of TNF-α and downregulation of survivin and mutant p53. Abstract:  BACKGROUND: In the present study, we investigated the effect of Origanum majorana ethanolic extract on the survival …

Continue reading “O. majorana may be a promising chemopreventive and therapeutic candidate against highly invasive triple negative p53 mutant breast cancer.”

PMID:  PLoS One. 2013 ;8(7):e68808. Epub 2013 Jul 10. PMID: 23874773 Abstract Title:  Anti-metastatic and anti-tumor growth effects of Origanum majorana on highly metastatic human breast cancer cells: inhibition of NFκB signaling and reduction of nitric oxide production. Abstract:  BACKGROUND: We have recently reported that Origanummajorana exhibits anticancer activity by promoting cell cycle arrest and …

Continue reading “These findings identify Origanum majorana as a promising chemopreventive and therapeutic candidate that modulate breast cancer growth and metastasis.”

PMID:  Nutrients. 2016 May 5 ;8(5). Epub 2016 May 5. PMID: 27164131 Abstract Title:  Origanum majorana Attenuates Nephrotoxicity of Cisplatin Anticancer Drug through Ameliorating Oxidative Stress. Abstract:  Despite the fact that cisplatin is an important anticancer drug, its clinical utilization is limited by nephrotoxicity during long term medication. Combined cisplatin chemotherapy with plant extracts can …

Continue reading “Origanum majorana attenuates nephrotoxicity of cisplatin anticancer drug through ameliorating oxidative stress.”

PMID:  Evid Based Complement Alternat Med. 2019 ;2019:2421695. Epub 2019 Jan 15. PMID: 30766611 Abstract Title:  ,, andEssential Oils: Chemical Composition, Antimicrobial and Antileishmanial Activity. Abstract:  The resistance mechanisms of bacteria and protozoans have evidenced the need of discover new compounds with potential pharmaceutical activity against pathogenic microorganisms. Medicinal plants have been for centuries a …

Continue reading “Cinnamomum zeylanicum, Origanum vulgare, and Curcuma longa essential oils: chemical composition, antimicrobial and antileishmanial activity.”

PMID:  Front Oncol. 2019 ;9:795. Epub 2019 Aug 21. PMID: 31497536 Abstract Title:  Ethanolic Extract Promotes Colorectal Cancer Cell Death by Triggering Abortive Autophagy and Activation of the Extrinsic Apoptotic Pathway. Abstract:  Colorectal cancer is considered as the third leading cause of cancer death. In the present study, we investigated the potential anticancer effect and …

Continue reading “These finding provide the basis for therapeutic potential of O. majorana in the treatment of colon cancer.”

PMID:  J Ethnopharmacol. 2019 Aug 27 ;246:112188. Epub 2019 Aug 27. PMID: 31470085 Abstract Title:  Antifungal and biofilm inhibitory effect of Cymbopogon citratus (lemongrass) essential oil on biofilm forming by Candida tropicalis isolates; an in vitro study. Abstract:  ETHNOPHARMACOLOGICAL RELEVANCE: Cymbopogon citratus (lemongrass) essential oil has been widely used as a traditional medicine and is …

Continue reading “Antifungal and biofilm inhibitory effect of lemongrass essential oil on biofilm forming by Candida tropicalis.”

PMID:  Environ Sci Pollut Res Int. 2019 Aug 29. Epub 2019 Aug 29. PMID: 31468354 Abstract Title:  Efficacy of different citrus essential oils to inhibit the growth and B1 aflatoxin biosynthesis of Aspergillus flavus. Abstract:  Food contamination by aflatoxin B1 (AFB1), produced by mycotoxigenic strains of Aspergillus spp., causes severe medical and economic implications. Essential …

Continue reading “Efficacy of different citrus essential oils to inhibit the growth and B1 aflatoxin biosynthesis of Aspergillus flavus.”