Anti-biofilm effect of selected essential oils and main components on mono- and polymicrobic bacterial cultures.

PMID:  Microorganisms. 2019 Sep 12 ;7(9). Epub 2019 Sep 12. PMID: 31547282 Abstract Title:  Anti-Biofilm Effect of Selected Essential Oils and Main Components on Mono- and Polymicrobic Bacterial Cultures. Abstract:  Biofilms are surface-associated microbial communities resistant to sanitizers and antimicrobials. Various interactions that can contribute to increased resistance occur between the populations in biofilms. These …

Characterization and macrophage immunomodulatory activity of two polysaccharides from the flowers of Paeonia suffruticosa Andr.

PMID:  Int J Biol Macromol. 2019 Mar 1 ;124:955-962. Epub 2018 Dec 4. PMID: 30529201 Abstract Title:  Characterization and macrophage immunomodulatory activity of two polysaccharides from the flowers of Paeonia suffruticosa Andr. Abstract:  Paeonia suffruticosa Andr. has a long history of cultivation in China and its flower possesses high nutritional and medicinal value. Characterization and …

Flower extracts from Paeonia decomposita and Paeonia ostii inhibit melanin synthesis.

PMID:  J Food Biochem. 2019 Apr ;43(4):e12777. Epub 2019 Jan 24. PMID: 31353606 Abstract Title:  Flower extracts from Paeonia decomposita and Paeonia ostii inhibit melanin synthesis via cAMP-CREB-associated melanogenesis signaling pathways in murine B16 melanoma cells. Abstract:  This investigation seeks to identify the effects of the EtOAc fractions of different flower parts of Paeonia decomposita …

Penta-O-galloyl-β-d-glucose could serve as a potent therapeutic agent for controlling obesity and obesity-related chronic inflammation.

PMID:  Chem Biol Interact. 2019 Apr 1 ;302:156-163. Epub 2019 Feb 2. PMID: 30721698 Abstract Title:  Penta-O-galloyl-β-d-glucose, a hydrolysable tannin from Radix Paeoniae Alba, inhibits adipogenesis and TNF-α-mediated inflammation in 3T3-L1 cells. Abstract:  Penta-O-galloyl-β-d-glucose (PGG) was purified and identified from Radix Paeoniae Alba by HSCCC and HPLC/ESI-MS, and its inhibitory effects on adipogenesis and TNF-α-induced …

Paeoniae Radix-containing herbal medicines might promote improvements in restless legs syndrome.

PMID:  Complement Ther Clin Pract. 2019 May ;35:329-341. Epub 2019 Mar 20. PMID: 31003678 Abstract Title:  Paeoniae Radix-containing herbal medicine for patients with restless legs syndrome: A systematic review and meta-analysis. Abstract:  BACKGROUND AND PURPOSE: Paeoniae Radix has been used for legs discomfort such as restless legs syndrome. The aim of this review is to …

Isolation of strong antioxidants from Paeonia officinalis roots and leaves and evaluation of their bioactivities.

PMID:  Antioxidants (Basel). 2019 Jul 27 ;8(8). Epub 2019 Jul 27. PMID: 31357649 Abstract Title:  Isolation of Strong Antioxidants fromRoots and Leaves and Evaluation of Their Bioactivities. Abstract:  extracts from leaves and roots were tested for their antioxidant potential using in vitro chemical (Folin-Ciocalteu, 2,2-diphenyl-1-picrylhydrazyl radical (DPPH), 2,2'-azino–3-ethylbenzothiazoline-6-sulfonic acid (ABTS), oxygen radical absorbance capacity (ORAC), …

Total glucosides of peony improve ovalbumin-induced allergic asthma by inhibiting mast cell degranulation.

PMID:  J Ethnopharmacol. 2019 Nov 15 ;244:112136. Epub 2019 Aug 1. PMID: 31377261 Abstract Title:  Total glucosides of peony improve ovalbumin-induced allergic asthma by inhibiting mast cell degranulation. Abstract:  ETHNOPHARMACOLOGICAL RELEVANCE: Paeonia lactiflora Pall. (peony) is a medicinal plant used in the Xiaoqinglong decoction, a commonly prescribed traditional Chinese medicine for asthma. The main active …

Paeonia lactiflora root extract suppresses cancer cachexia.

PMID:  J Ethnopharmacol. 2019 Sep 7 ;246:112222. Epub 2019 Sep 7. PMID: 31505213 Abstract Title:  Paeonia lactiflora root extract suppresses cancer cachexia by down-regulating muscular NF-κB signalling and muscle-specific E3 ubiquitin ligases in cancer-bearing mice. Abstract:  ETHNOPHARMACOLOGICAL RELEVANCE: The dried root of Paeonia lactiflora Pall. (Radix Paeoniae) has been traditionally used to treat various inflammatory …

Paeonol antagonizes oncogenesis of osteosarcoma by inhibiting the function of TLR4/MAPK/NF-κB pathway.

PMID:  Acta Histochem. 2019 Oct 3:151455. Epub 2019 Oct 3. PMID: 31587886 Abstract Title:  Paeonol antagonizes oncogenesis of osteosarcoma by inhibiting the function of TLR4/MAPK/NF-κB pathway. Abstract:  As the the major functional component of Paeonia suffruticosa, paeonol (PAE) has shown its potential to inhibit the progression of multiple cancer types. In the current study, the …

Mechanisms of Paeonia lactiflora in treatment of ulcerative colitis.

PMID:  Med Sci Monit. 2019 Oct 9 ;25:7574-7580. Epub 2019 Oct 9. PMID: 31594914 Abstract Title:  Mechanisms of Paeonia lactiflora in Treatment of Ulcerative Colitis: A Network Pharmacological Study. Abstract:  BACKGROUND Paeonia lactiflora is the main active ingredient of peony decoction, which is used to treat ulcerative colitis (UC) in traditional Chinese medicine (TCM). Network …

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