PMID: Biosci Biotechnol Biochem. 2019 Sep ;83(9):1729-1739. Epub 2019 Apr 22. PMID: 31010399 Abstract Title: Lupeol suppresses migration and invasionp38/MAPK and PI3K/Akt signaling pathways in human osteosarcoma U-2 OS cells. Abstract: Lupeol, one of the common components from the fruits and natural foods, has been reported to exert antitumor activities in many human cancer cell …
Continue reading “Lupeol can be used in anti-metastasis of human osteosarcoma cells.”
PMID: Parasitology. 2019 Sep ;146(11):1440-1450. Epub 2019 Jun 13. PMID: 31104636 Abstract Title: Lupeol induces immunity and protective efficacy in a murine model against visceral leishmaniasis. Abstract: The available chemotherapeutics for the cure of visceral leishmaniasis (VL) are linked with many detrimental effects. Moreover, VL is associated with the suppression of protective Th1 immune response …
PMID: Int J Oncol. 2019 Jul ;55(1):320-330. Epub 2019 May 7. PMID: 31115519 Abstract Title: Suppression of EGFR/STAT3 activity by lupeol contributes to the induction of the apoptosis of human non‑small cell lung cancer cells. Abstract: The aim of this study was to investigate the underlying mechanisms responsible for the anticancer effects of lupeol on …
PMID: Drug Des Devel Ther. 2019 ;13:1501-1513. Epub 2019 May 6. PMID: 31123393 Abstract Title: In silico and in vitro studies of lupeol and iso-orientin as potential antidiabetic agents in a rat model. Abstract: In silico characterization can help to explain the interaction between molecules and predict three-dimensional structures. Various studies have confirmed the glucose-lowering …
PMID: Oxid Med Cell Longev. 2019 ;2019:3182627. Epub 2019 May 9. PMID: 31210838 Abstract Title: Lupeol, a Dietary Triterpene, Enhances Wound Healing in Streptozotocin-Induced Hyperglycemic Rats with Modulatory Effects on Inflammation, Oxidative Stress, and Angiogenesis. Abstract: Impaired wound healing is a debilitating complication of diabetes that leads to significant morbidity, particularly foot ulcers. Natural products …
Continue reading “Lupeol enhances wound healing in streptozotocin-induced hyperglycaemia.”
PMID: Heliyon. 2019 Aug ;5(8):e02107. Epub 2019 Aug 2. PMID: 31417967 Abstract Title: Lupeol alters viability of SK-RC-45 (Renal cell carcinoma cell line) by modulating its mitochondrial dynamics. Abstract: Renal cell carcinoma (RCC) is the most common kidney cancer leading to 140,000 deaths per year. Among all RCCs 80% evolve from the epithelial proximal tubular …
PMID: Int Urol Nephrol. 2016 Nov ;48(11):1873-1880. Epub 2016 Jun 24. PMID: 27342654 Abstract Title: Clinical study of total glucosides of paeony for the treatment of diabetic kidney disease in patients with diabetes mellitus. Abstract: BACKGROUND AND AIM: Total glucosides of paeony (TGP), an active compound extracted from dried roots of Paeonia lactiflora Pall, have …
PMID: Int Immunopharmacol. 2016 Jul ;36:67-72. Epub 2016 Apr 22. PMID: 27107800 Abstract Title: Total glucosides of paeony (TGP) inhibits the production of inflammatory cytokines in oral lichen planus by suppressing the NF-κB signaling pathway. Abstract: Total glucosides of paeony (TGP) is a bioactive compound extracted from paeony roots and has been widely used to …
PMID: Int Immunopharmacol. 2016 Oct ;39:314-319. Epub 2016 Aug 11. PMID: 27517517 Abstract Title: Clinical and immunological consequences of total glucosides of paeony treatment in Sjögren's syndrome: A randomized controlled pilot trial. Abstract: BACKGROUND: The total glucosides of paeony (TGP) can inhibit inflammation and alleviate symptoms in autoimmune diseases. This study investigated the clinical and …
PMID: Complement Ther Med. 2017 Oct ;34:46-56. Epub 2017 Jul 26. PMID: 28917375 Abstract Title: Total glucosides of paeony for rheumatoid arthritis: A systematic review of randomized controlled trials. Abstract: BACKGROUND: Total glucosides of paeony (TGP) is commonly used to treat rheumatoid arthritis (RA) in China. However, clinical practice hasn't been well informed by evidence …
Continue reading “Total glucosides of paeony could be beneficial for rheumatoid arthritis.”
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