In vitro antimicrobial activity of frankincense oils from Boswellia sacra.

PMID:  Antibiotics (Basel). 2020 Apr 20 ;9(4). Epub 2020 Apr 20. PMID: 32325952 Abstract Title:  In Vitro Antimicrobial Activity of Frankincense Oils fromGrown in Different Locations of the Dhofar Region (Oman). Abstract:  Frankincense essential oils fromhave been commonly used to treat microbial infections from as early as the 11th century. The main feature of the …

Silymarin, boswellic acid and curcumin enriched dietetic formulation reduces the growth of inherited intestinal polyps.

PMID:  World J Gastroenterol. 2020 Apr 14 ;26(14):1601-1612. PMID: 32327909 Abstract Title:  Silymarin, boswellic acid and curcumin enriched dietetic formulation reduces the growth of inherited intestinal polyps in an animal model. Abstract:  BACKGROUND: Some substances of plant origin have been reported to exert an effect in reducing intestinal neoplasm development, especially in animal models. Adenomatous …

Triterpenic acids as non-competitive α-glucosidase inhibitors from Boswellia elongate.

PMID:  Biomolecules. 2020 May 12 ;10(5). Epub 2020 May 12. PMID: 32408614 Abstract Title:  Triterpenic Acids as Non-Competitiveα-Glucosidase Inhibitors fromwith Structure-Activity Relationship: In Vitro and In Silico Studies. Abstract:  Fourteen triterpene acids, viz., three tirucallane-type (-), eight ursane-type (-), two oleanane-type (,) and one lupane type (), along with boswellic aldehyde (),α-amyrine (), epi-amyrine (), …

Genus Boswellia as a new candidate for neurodegenerative disorders.

PMID:  Iran J Basic Med Sci. 2020 Mar ;23(3):277-286. PMID: 32440312 Abstract Title:  Genusas a new candidate for neurodegenerative disorders. Abstract:  Neurodegenerative diseases, characterized by progressive loss of neurons, share common mechanisms such as apoptotic cell death, mitochondrial dysfunction, inflammation, and oxidative stress. Genusis a genus in the Burseraceae family. It comprises several species traditionally …

Licochalcone A selectively resensitizes ABCG2-overexpressing multidrug-resistant cancer cells to chemotherapeutic drugs.

PMID:  J Nat Prod. 2020 May 22 ;83(5):1461-1472. Epub 2020 Apr 29. PMID: 32347726 Abstract Title:  Licochalcone A Selectively Resensitizes ABCG2-Overexpressing Multidrug-Resistant Cancer Cells to Chemotherapeutic Drugs. Abstract:  The overexpression of the ATP-binding cassette (ABC) transporter ABCG2 has been linked to clinical multidrug resistance in solid tumors and blood cancers, which remains a significant obstacle …

Vasorelaxation effect of 18β-glycyrrhetinic acid on the thoracic aorta of rats.

PMID:  Pharmazie. 2019 12 1 ;74(12):751-754. PMID: 31907117 Abstract Title:  Vasorelaxation effect of 18β-glycyrrhetinic acid on the thoracic aorta of rats: proposed mechanism. Abstract:  18β-Glycyrrhetinic acid (18β-GA) is an effective component extracted from the traditional Chinese medicine(Leguminosae) and has various biological activities. This study was performed to investigate the vasodilatory effects of 18β-GA on isolated …

18α-glycyrrhetinic acid ameliorates fructose-induced nephropathy.

PMID:  Biomed Pharmacother. 2020 May ;125:109702. Epub 2020 Feb 25. PMID: 32106383 Abstract Title:  18α-Glycyrrhetinic acid (GA) ameliorates fructose-induced nephropathy in mice by suppressing oxidative stress, dyslipidemia and inflammation. Abstract:  Excessive fructose (FRU) intake can result in insulin resistance and metabolic disorder, which are related to renal injury.18α-Glycyrrhetinic acid (GA) is a bioactive component mainly …

18β-glycyrrhetinic acid acts through hepatocyte nuclear factor 4 alpha to modulate lipid and carbohydrate metabolism.

PMID:  Pharmacol Res. 2020 Apr 28 ;157:104840. Epub 2020 Apr 28. PMID: 32353589 Abstract Title:  18β-Glycyrrhetinic acid acts through hepatocyte nuclear factor 4 alpha to modulate lipid and carbohydrate metabolism. Abstract:  Hepatocyte nuclear factor 4 alpha (HNF4α) regulates the expression of essential genes involved in very-low-density lipoprotein (VLDL) homeostasis and gluconeogenesis. 18β-glycyrrhetinic acid (GA) is an …

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