3,3′-Diindolylmethane nanoencapsulation improves its antinociceptive action.

PMID:  Colloids Surf B Biointerfaces. 2019 Sep 1 ;181:295-304. Epub 2019 May 25. PMID: 31154140 Abstract Title:  3,3'-Diindolylmethane nanoencapsulation improves its antinociceptive action: Physicochemical and behavioral studies. Abstract:  This study aimed to characterize the physicochemical properties of 3,3'-diindolylmethane (DIM)-loaded nanocapsules (NCs) as well as the antinociceptive effect using distinct animal models (hot plate test, formalin-induced …

Statin discontinuation was associated with a 33% increased risk of admission for cardiovascular event in 75-year-old primary prevention patients.

PMID:  Eur Heart J. 2019 Jul 30. Epub 2019 Jul 30. PMID: 31362307 Abstract Title:  Cardiovascular effect of discontinuing statins for primary prevention at the age of 75 years: a nationwide population-based cohort study in France. Abstract:  AIMS: The role of statin therapy in primary prevention of cardiovascular disease in persons older than 75 years remains …

Oral supplementation of L-glutathione prevents UVB-induced melanogenesis and oxidative stress.

PMID:  Exp Anim. 2019 Jun 26. Epub 2019 Jun 26. PMID: 31243189 Abstract Title:  Oral supplementation of L-glutathione prevents UVB-induced melanogenesis and oxidative stress in BALB/c mice. Abstract:  Dietary antioxidant supplements such as L-glutathione have gained considerable attention in dermatology and cosmeceutical fields. L-Glutathione possesses antiaging, antimelanogenic, antioxidant, and anticancer properties. This study aimed to …

N-acetyl-cysteine supplementation improves functional connectivity within the cingulate cortex in early psychosis.

PMID:  Int J Neuropsychopharmacol. 2019 Aug 1 ;22(8):478-487. PMID: 31283822 Abstract Title:  N-Acetyl-Cysteine Supplementation Improves Functional Connectivity Within the Cingulate Cortex in Early Psychosis: A Pilot Study. Abstract:  BACKGROUND: There is increasing evidence that redox dysregulation, which can lead to oxidative stress and eventually to impairment of oligodendrocytes and parvalbumin interneurons, may underlie brain connectivity …

Baru almond supplementation increased the GPx activity in overweight and obese women.

PMID:  Nutrients. 2019 Jul 30 ;11(8). Epub 2019 Jul 30. PMID: 31366053 Abstract Title:  Baru Almonds Increase the Activity of Glutathione Peroxidase in Overweight and Obese Women: A Randomized, Placebo-Controlled Trial. Abstract:  BACKGROUND: Obesity-induced inflammation is frequently associated with higher oxidative stress. In vitro and experimental studies have considered baru almonds (Dipteryx alata Vog) as …

Liposomal glutathione as a promising candidate for immunological rheumatoid arthritis therapy.

PMID:  Heliyon. 2019 Jul ;5(7):e02162. Epub 2019 Jul 27. PMID: 31384691 Abstract Title:  Liposomal glutathione as a promising candidate for immunological rheumatoid arthritis therapy. Abstract:  Nano-medicine can passively accumulate in chronic inflammatory tissues via the enhanced permeability and retention phenomenon, or by being conjugated with a ligand that can bind to receptors over expressed by …

Effects of N-acetyl cysteine, vitamin E and vitamin C on liver glutathione levels following amiodarone treatment in rats.

PMID:  Kardiochir Torakochirurgia Pol. 2019 Jul ;16(2):88-92. Epub 2019 Jun 28. PMID: 31410096 Abstract Title:  Effects of N-acetyl cysteine, vitamin E and vitamin C on liver glutathione levels following amiodarone treatment in rats. Abstract:  Introduction: Amiodarone, a pharmaceutical extensively used to suppress atrial and ventricular tachyarrhythmias, is also known to cause many side effects on …

Mindfulness meditation training can effectively alleviate the symptoms of anxiety and depression and improve the quality of sleep in perimenopausal women.

PMID:  Nan Fang Yi Ke Da Xue Xue Bao. 2019 Aug 30 ;39(8):998-1002. PMID: 31511223 Abstract Title:  [Effect of mindfulness meditation training on anxiety, depression and sleep quality in perimenopausal women]. Abstract:  OBJECTIVE: To explore the effect of mindfulness meditation training for improving anxiety, depression and sleep disorders in perimenopausal women.METHODS: Intervention by menopause meditation …

The sour side of vitamin C might mediate neuroprotective, anticonvulsive and antidepressant-like effects.

PMID:  Med Hypotheses. 2019 Oct ;131:109320. Epub 2019 Jul 20. PMID: 31443769 Abstract Title:  The sour side of vitamin C might mediate neuroprotective, anticonvulsive and antidepressant-like effects. Abstract:  In animal experiments, neuroprotective, anticonvulsive and antidepressant-like properties have been increasingly attributed to administrations of ascorbic acid (AA, vitamin C) in at least medium (low millimolar) doses, …

These results suggest that cranberry ameliorates high fat diet-induced metabolic disturbances.

PMID:  Biol Pharm Bull. 2019 ;42(8):1295-1302. PMID: 31366865 Abstract Title:  Cranberry Attenuates Progression of Non-alcoholic Fatty Liver Disease Induced by High-Fat Diet in Mice. Abstract:  Obesity is characterized by abnormal or excessive fat accumulation, which leads to the development of metabolic syndrome. Because oxidative stress is increased in obesity, antioxidants are regarded as suitable agents …

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