Ginsenoside Rg3 reduced transforming growth factor-β1-induced epithelial-mesenchymal transition in HMrSV5 human peritoneal cells.

PMID:  Med Sci Monit. 2019 Sep 17 ;25:6972-6979. Epub 2019 Sep 17. PMID: 31527568 Abstract Title:  Ginsenoside Rg3 Reduces Epithelial-Mesenchymal Transition Induced by Transforming Growth Factor-β1 by Inactivation of AKT in HMrSV5 Peritoneal Mesothelial Cells. Abstract:  BACKGROUND Ginsenosides, including ginsenoside Rg3, are components of Panax ginseng C.A. Meyer (Araliaceae) used in traditional Chinese medicine. Long-term …

Ginsenoside Rh1 inhibits colorectal cancer cell migration and invasion in vitro and tumor growth in vivo.

PMID:  Oncol Lett. 2019 Oct ;18(4):4160-4166. Epub 2019 Aug 14. PMID: 31579419 Abstract Title:  Ginsenoside Rh1 inhibits colorectal cancer cell migration and invasionand tumor growth. Abstract:  Colorectal cancer (CRC) is the third leading cause of cancer-associated mortality worldwide. Ginsenoside Rh1 (Rh1) is a traditional medicine monomer with antitumor activity; however, the effects of Rh1 in …

How Safe Is Your CBD? The FDA Is Asking—And You Should, Too

There’s little doubt that CBD has become a way of life—a recent survey found that an estimated 64 million Americans have tried the chemical compound found in the cannabis plant that’s been linked to numerous wellness benefits, from reducing inflammation and sleeplessness to mitigating anxiety and acne. But similar to the supplement industry, CBD is largely unregulated. …

These results indicate that Ginsenoside Rg3 suppresses endometriosis.

PMID:  J Gynecol Obstet Hum Reprod. 2019 Sep 26:101642. Epub 2019 Sep 26. PMID: 31563698 Abstract Title:  Ginsenoside Rg3 attenuates endometriosis by inhibiting the viability of human ectopic endometrial stromal cells through the nuclear factor-kappaB signaling pathway. Abstract:  OBJECTIVE: To investigate the effects of ginsenoside Rg3 on human ectopic endometriotic stromal cells in vitro.MATERIALS AND …

Ginsenoside Rb3 regulates energy metabolism and apoptosis in cardiomyocytes via activating PPARα pathway.

PMID:  Biomed Pharmacother. 2019 Sep 29 ;120:109487. Epub 2019 Sep 29. PMID: 31577975 Abstract Title:  Ginsenoside Rb3 regulates energy metabolism and apoptosis in cardiomyocytes via activating PPARα pathway. Abstract:  Heart failure (HF) leads to an increase in morbidity and mortality globally. Disorders of energy metabolism and apoptosis of cardiomyocytes are critically involved in the progression …

β-Sitosterol derived compound from onion husks non-polar fraction reduces quorum sensing controlled virulence and biofilm production.

PMID:  Saudi Pharm J. 2019 Jul ;27(5):664-672. Epub 2019 Apr 4. PMID: 31297021 Abstract Title:  -Sitosterol derived compound from onion husks non-polar fraction reduces quorum sensing controlled virulence and biofilm production. Abstract:  Quorum sensing is an important regulatory factor ofvirulence induction such as BF, motility, formations of proteases, pyocyanin, and some toxins. The aim of …

Cytotoxic and antiproliferative effects of thymoquinone on rat C6 glioma cells depend on oxidative stress.

PMID:  Mol Cell Biochem. 2019 Sep 6. Epub 2019 Sep 6. PMID: 31493190 Abstract Title:  Cytotoxic and antiproliferative effects of thymoquinone on rat C6 glioma cells depend on oxidative stress. Abstract:  Thymoquinone (TQ) is a highly perspective chemotherapeutic agent against gliomas and glioblastomas because of its ability to cross the blood-brain barrier and its selective …

Thymoquinone ameliorates oxidative damage and histopathological changes of developing brain neurotoxicity.

PMID:  J Histotechnol. 2019 Sep ;42(3):116-127. Epub 2019 Jul 24. PMID: 31492091 Abstract Title:  Thymoquinone ameliorates oxidative damage and histopathological changes of developing brain neurotoxicity. Abstract:  Lead (Pb) toxicity is known to be a chief environmental health issue, especially for pregnant women and young children. Today, the use of medicinal herbs in the treatment of …

Thymoquinone loaded mesoporous silica nanoparticles inhibit cell invasion and enhance in vitro cytotoxicity.

PMID:  Mater Sci Eng C Mater Biol Appl. 2019 Nov ;104:109881. Epub 2019 Jun 11. PMID: 31499940 Abstract Title:  Thymoquinone loaded mesoporous silica nanoparticles retard cell invasion and enhance in vitro cytotoxicity due to ROS mediated apoptosis in HeLa and MCF-7 cell lines. Abstract:  Thymoquinone (TQ) loaded monodispersed mesoporous silica nanoparticles (TQ-MSNPs) with size of …

These findings confirm that thymoquinone has the potential to be used to combat L. monocytogenes infection.

PMID:  Front Cell Infect Microbiol. 2019 ;9:304. Epub 2019 Aug 27. PMID: 31508379 Abstract Title:  Inhibitory Effect of Thymoquinone onATCC 19115 Biofilm Formation and Virulence Attributes Critical for Human Infection. Abstract:  This study aimed to determine the antimicrobial activity of thymoquinone (TQ) against, and to examine its inhibitory effects on biofilm formation, motility, hemolysin production, …

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