Astragaloside IV protects endothelial progenitor cells from the damage of oxidized low-density lipoprotein.

PMID:  Drug Des Devel Ther. 2019 ;13:2579-2589. Epub 2019 Jul 29. PMID: 31440038 Abstract Title:  Astragaloside IV protects endothelial progenitor cells from the damage of ox-LDL via the LOX-1/NLRP3 inflammasome pathway. Abstract:  Functional impairment of endothelial progenitor cells (EPCs) is frequently observed in patients with diabetic vascular complications. Astragaloside IV (ASV) has a significant protective …

Astragaloside III enhances anti-tumor response of NK cells by elevating NKG2D and IFN-γ.

PMID:  Front Pharmacol. 2019 ;10:898. Epub 2019 Aug 13. PMID: 31456687 Abstract Title:  Astragaloside III Enhances Anti-Tumor Response of NK Cells by Elevating NKG2D and IFN-γ. Abstract:  Natural killer (NK) cells play an irreplaceable role in the development of colon cancer, in which antitumor function of NK cells was impaired. Astragaloside III is a natural …

Astragaloside IV protects ethanol-induced gastric mucosal injury.

PMID:  Front Pharmacol. 2019 ;10:894. Epub 2019 Aug 15. PMID: 31474858 Abstract Title:  Astragaloside IV Protects Ethanol-Induced Gastric Mucosal Injury by Preventing Mitochondrial Oxidative Stress and the Activation of Mitochondrial Pathway Apoptosis in Rats. Abstract:  Alcohol consumption affects gastric mucosa by multiple and complex mechanisms depending either by direct contact of ethanol or by indirect …

Inhibitory effects of astragaloside IV on silica-induced pulmonary fibrosis.

PMID:  Biomed Pharmacother. 2019 Sep 2 ;119:109387. Epub 2019 Sep 2. PMID: 31487583 Abstract Title:  Inhibitory effects of astragaloside IV on silica-induced pulmonary fibrosis via inactivating TGF-β1/Smad3 signaling. Abstract:  PURPOSE: To observe the effect of astragaloside ASV (ASV) on silicosis fibroblasts, and further investigate its regulatory mechanism on TGF-β1/Smad3 signaling pathway.METHODS: Silica-induced rats model was …

Astragaloside IV attenuates renal fibrosis through repressing epithelial-to-mesenchymal transition.

PMID:  Am J Transl Res. 2019 ;11(8):5029-5038. Epub 2019 Aug 15. PMID: 31497219 Abstract Title:  Astragaloside IV attenuates renal fibrosis through repressing epithelial-to-mesenchymal transition by inhibiting microRNA-192 expression:andstudies. Abstract:  The aim of this study was to investigate the effect of Astragaloside IV (AS-IV) on renal fibrosisand, and further to explore the underlying mechanism. To investigate …

Astragaloside IV alleviates the myocardial damage induced by lipopolysaccharide.

PMID:  Med Sci Monit. 2019 Sep 23 ;25:7158-7168. Epub 2019 Sep 23. PMID: 31545785 Abstract Title:  Astragaloside IV Alleviates the Myocardial Damage Induced by Lipopolysaccharide via the Toll-Like Receptor 4 (TLR4)/Nuclear Factor kappa B (NF-κB)/Proliferator-Activated Receptor α (PPARα) Signaling Pathway. Abstract:  BACKGROUND We previously reported that astragaloside IV (As-IV) can alleviate myocardial damage induced by …

Astragaloside IV attenuates lipopolysaccharides-induced pulmonary epithelial cell injury through inhibiting autophagy.

PMID:  Pharmacology. 2019 Sep 25:1-12. Epub 2019 Sep 25. PMID: 31554002 Abstract Title:  Astragaloside IV Attenuates Lipopolysaccharides-Induced Pulmonary Epithelial Cell Injury through Inhibiting Autophagy. Abstract:  BACKGROUND: Astragaloside IV has shown its promising effect on acute respiratory distress syndrome (ARDS).OBJECTIVES: We aim to explore whether astragaloside IV is effective for ARDS treatment in a lipopolysaccharides (LPS)-induced …

Electromagnetic irradiation from mobile phones induces the activation of the ERK cascade and thereby induces transcription and other cellular processes.

PMID:  Biochem J. 2007 Aug 1 ;405(3):559-68. PMID: 17456048 Abstract Title:  Mechanism of short-term ERK activation by electromagnetic fields at mobile phone frequencies. Abstract:  The exposure to non-thermal microwave electromagnetic fields generated by mobile phones affects the expression of many proteins. This effect on transcription and protein stability can be mediated by the MAPK (mitogen-activated …

Higher levels of irreversible oxidative damage were observed in the major lymphoid organs of immature rats than in mature rats.

PMID:  Arch Med Res. 2011 May ;42(4):261-7. PMID: 21820603 Abstract Title:  Effects of a 900-MHz electromagnetic field on oxidative stress parameters in rat lymphoid organs, polymorphonuclear leukocytes and plasma. Abstract:  BACKGROUND AND AIMS: The present study investigated the effects of a 900-MHz electromagnetic field (EMF) for 2 h/day for 45 days on lymphoid organs (spleen, …

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