Category Archives: Uncategorized

PMID:  Ear Nose Throat J. 2019 Sep 26:145561319866826. Epub 2019 Sep 26. PMID: 31558064 Abstract Title:  Investigation of Astaxanthin Effect on Cisplatin Ototoxicity in Rats by Using Otoacoustic Emission, Total Antioxidant Capacity, and Histopathological Methods. Abstract:  BACKGROUND: Cisplatin-induced ototoxicity is related to oxidative stress. Astaxanthin is one of the most powerful antioxidants in nature.AIMS/OBJECTIVES: To …

Continue reading “Astaxanthin may have protective effect against cisplatin-induced ototoxicity.”

PMID:  Food Chem Toxicol. 2019 Jul ;129:13-21. Epub 2019 Apr 20. PMID: 31014900 Abstract Title:  Cyanidin-3-O-glucoside protects against cadmium-induced dysfunction of sex hormone secretion via the regulation of hypothalamus-pituitary-gonadal axis in male pubertal mice. Abstract:  Cadmium (Cd) has been generally recognized as an endocrine-disrupting chemical for its toxic effects on the hypothalamus-pituitary-gonadal (HPG) axis accompanied …

Continue reading “Consumption of anthocyanins can be protective against metal-induced male reproductive dysfunction.”

PMID:  Inflamm Bowel Dis. 2019 Aug 20 ;25(9):1510-1521. PMID: 31107535 Abstract Title:  Low Dose of Cyanidin-3-O-Glucoside Alleviated Dextran Sulfate Sodium-Induced Colitis, Mediated by CD169+ Macrophage Pathway. Abstract:  BACKGROUND: Inflammatory bowel disease (IBD) is a chronic disease of the intestinal tract in which excessive activation of inflammatory response is correlated. Cyanidin-3-O-glucoside (C3G) is a powerful anti-inflammatory …

Continue reading “The study is the first to demonstrate strong effects of cyanidin-3-O-glucosideto alleviate DSS-induced colonic damage.”

PMID:  J Food Sci. 2019 Jun ;84(6):1638-1645. Epub 2019 May 29. PMID: 31141616 Abstract Title:  Antioxidant and Antiproliferative Activities of Cyanidin-3-O-Glucoside (C3G) Liposome in Caco-2 Cells Cultivated in 2D and 3D Cell Culture Models. Abstract:  The aim of this study was to obtain adequate and detailed information about the antioxidant and antiproliferative activities of C3G …

Continue reading “Antioxidant and antiproliferative activities of cyanidin-3-O-glucoside liposome in caco-2 cells.”

PMID:  BMC Complement Altern Med. 2019 Sep 5 ;19(1):242. Epub 2019 Sep 5. PMID: 31488210 Abstract Title:  Cyanidin-3-rutinoside acts as a natural inhibitor of intestinal lipid digestion and absorption. Abstract:  BACKGROUND: Cyanidin-3-rutinoside (C3R), a naturally occurring anthocyanin, possesses anti-oxidant, anti-hyperglycemic, anti-glycation and cardioprotective properties. However, its mechanisms responsible for anti-hyperlipidemic activity have not been fully …

Continue reading “Cyanidin-3-rutinoside acts as a natural inhibitor of intestinal lipid digestion and absorption.”

PMID:  Front Pharmacol. 2016 ;7:301. Epub 2016 Sep 7. PMID: 27656146 Abstract Title:  Protective Effect of Cyanidin-3-O-Glucoside against Ultraviolet B Radiation-Induced Cell Damage in Human HaCaT Keratinocytes. Abstract:  Ultraviolet radiation is the major environmental harmful factor that has emotional impact on human skin. The aim of the present study was to determine the mechanism of …

Continue reading “This study provides a theoretical basis for the use of cyanidin-3-O-glucoside in the fight against light damage.”

PMID:  Food Chem Toxicol. 2018 Oct ;120:104-111. Epub 2018 May 25. PMID: 29803697 Abstract Title:  Cyanidin ameliorates endotoxin-induced myocardial toxicity by modulating inflammation and oxidative stress through mitochondria and other factors. Abstract:  Cyanidin, an anthocyanin pigment, demonstrates anti-oxidant and anti-inflammatory properties. Here, we examined the mechanistic role of cyanidin in endotoxin induced myocardial injury in …

Continue reading “Cyanidin ameliorates endotoxin-induced myocardial toxicity.”

PMID:  Acta Pharmacol Sin. 2018 Sep ;39(9):1439-1452. Epub 2018 Apr 19. PMID: 29671417 Abstract Title:  Cyanidin attenuates Aβ-induced neuroinflammation by suppressing NF-κB activity downstream of TLR4/NOX4 in human neuroblastoma cells. Abstract:  Cyanidin is polyphenolic pigment found in plants. We have previously demonstrated that cyanidin protects nerve cells against Aβ-induced toxicity by decreasing oxidative stress and …

Continue reading “Inhibition of TLR4 by cyanidin could be beneficial in preventing neuronal cell death in the process of Alzheimer’s disease.”

PMID:  Neural Regen Res. 2016 May ;11(5):795-800. PMID: 27335564 Abstract Title:  Cyanidin suppresses amyloid beta-induced neurotoxicity by inhibiting reactive oxygen species-mediated DNA damage and apoptosis in PC12 cells. Abstract:  Amyloid beta (Aβ)-induced oxidative stress is a major pathologic hallmark of Alzheimer's disease. Cyanidin, a natural flavonoid compound, is neuroprotective against oxidative damage-mediated degeneration. However, its …

Continue reading “Cyanidin suppresses amyloid beta-induced neurotoxicity.”

PMID:  J Food Sci Technol. 2016 Feb ;53(2):968-76. Epub 2016 Jan 25. PMID: 27162376 Abstract Title:  Cyanidin inhibits quorum signalling pathway of a food borne opportunistic pathogen. Abstract:  Quorum sensing (QS) is the process of population dependent cell to cell communication used by bacteria to regulate their phenotypic characteristics. Key virulence factors that determine the …

Continue reading “Cyanidin inhibits quorum signalling pathway of a food borne opportunistic pathogen.”