Category Archives: Uncategorized

PMID:  Food Funct. 2019 Sep 1 ;10(9):5644-5655. Epub 2019 Aug 21. PMID: 31433413 Abstract Title:  Fucoxanthin modulates cecal and fecal microbiota differently based on diet. Abstract:  Obesity is a major health concern worldwide and is considered to be associated with disruption of host-microbial homeostasis, especially microbiota composition in the gastrointestinal tract. Use of microbiota-directed foods …

Continue reading “Fucoxanthin modulates cecal and fecal microbiota differently based on diet.”

PMID:  Int J Mol Sci. 2019 Sep 11 ;20(18). Epub 2019 Sep 11. PMID: 31514311 Abstract Title:  Fucoxanthin-Rich Brown Algae Extract Improves Male Reproductive Function on Streptozotocin-Nicotinamide-Induced Diabetic Rat Model. Abstract:  Hypogonadism and oxidative stress are occurring commonly in men with diabetes and associated male infertility. This study aimed to investigate the capability of anti-oxidative …

Continue reading “Fucoxanthin-rich brown algae extract improves male reproductive function in a diabetes model.”

PMID:  Front Pharmacol. 2019 ;10:906. Epub 2019 Aug 28. PMID: 31555126 Abstract Title:  Fucoxanthin, a Marine Xanthophyll Isolated FromND-8: Preventive Anti-Inflammatory Effect in a Mouse Model of Sepsis. Abstract:  Fucoxanthin (FX), a xanthophyll pigment which occurs in marine brown algae with remarkable biological properties, has been proven to be safe for consumption by animals. Although …

Continue reading “Fucoxanthin had anti-inflammatory effects in a model of sepsis.”

PMID:  Biomed Pharmacother. 2019 Sep 18 ;120:109443. Epub 2019 Sep 18. PMID: 31541884 Abstract Title:  Rosmarinic acid inhibits proliferation and invasion of hepatocellular carcinoma cells SMMC 7721 via PI3K/AKT/mTOR signal pathway. Abstract:  OBJECTIVE: To investigate the effect of rosmarinic acid (RosA) on hepatocellular carcinoma cell in vivo and in vitro and to explore its possible …

Continue reading “Rosmarinic acid inhibits proliferation and invasion of hepatocellular carcinoma cells.”

PMID:  Diabetologia. 2018 06 ;61(6):1282-1294. Epub 2018 Apr 18. PMID: 29671031 Abstract Title:  Short-term decreased physical activity with increased sedentary behaviour causes metabolic derangements and altered body composition: effects in individuals with and without a first-degree relative with type 2 diabetes. Abstract:  AIMS/HYPOTHESIS: Low physical activity levels and sedentary behaviour are associated with obesity, insulin …

Continue reading “A short-term reduction in physical activity with increased sedentary behaviour leads to a reversible reduction in multi-organ insulin sensitivity and cardiorespiratory fitness.”

PMID:  Br J Pharmacol. 2008 May ;154(1):165-73. Epub 2008 Mar 10. PMID: 18332856 Abstract Title:  Anti-inflammatory effects of liquiritigenin as a consequence of the inhibition of NF-kappaB-dependent iNOS and proinflammatory cytokines production. Abstract:  BACKGROUND AND PURPOSE: Glycyrrhizae radix has been widely used as a cytoprotective, plant-derived medicine. We have identified a flavanoid, liquiritigenin, as an …

Continue reading “These results demonstrate that liquiritigenin exerts anti-inflammatory effects.”

PMID:  Int Immunopharmacol. 2009 May ;9(5):632-8. Epub 2009 Mar 3. PMID: 19264152 Abstract Title:  Liquiritigenin, a licorice flavonoid, helps mice resist disseminated candidiasis due to Candida albicans by Th1 immune response, whereas liquiritin, its glycoside form, does not. Abstract:  Licorice (the root of Glycyrrhizae plant) has been used as an oriental herbal medicine for thousands …

Continue reading “Liquiritigenin protects mice against disseminated candidiasis by the CD4+ Th1 immune response.”

PMID:  Acta Pharmacol Sin. 2009 Jul ;30(7):899-906. PMID: 19574995 Abstract Title:  Liquiritigenin inhibits Abeta(25-35)-induced neurotoxicity and secretion of Abeta(1-40) in rat hippocampal neurons. Abstract:  AIM: To examine whether liquiritigenin, a newly found agonist of selective estrogen receptor-beta, has neuroprotective activity against beta-amyloid peptide (Abeta) in rat hippocampal neurons.METHODS: Primary cultures of rat hippocampal neurons were …

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PMID:  Behav Brain Res. 2010 Jun 26 ;210(1):24-31. Epub 2010 Feb 1. PMID: 20117143 Abstract Title:  Effects of liquiritigenin treatment on the learning and memory deficits induced by amyloid beta-peptide (25-35) in rats. Abstract:  Considerable evidence has emerged supporting the neuroprotective and cognition-preserving effects of estrogen, but these benefits are complicated by the evidence that …

Continue reading “Effects of liquiritigenin treatment on the learning and memory deficits induced by amyloid beta-peptide (25-35) in rats.”

PMID:  Phytother Res. 2011 Feb ;25(2):277-83. PMID: 20658471 Abstract Title:  Liquiritigenin induces mitochondria-mediated apoptosis via cytochrome c release and caspases activation in HeLa Cells. Abstract:  It has been demonstrated that many flavonoids possess a potent and broad spectrum of antitumor activity. Liquiritigenin is a flavanone extracted from Glycyrrhizae. This study investigated the effects of liquiritigenin …

Continue reading “Liquiritigenin induces mitochondria-mediated apoptosis via cytochrome c release and caspases activation in HeLa Cells.”