Apple polyphenol extracts prevent damage to human gastric epithelial cells.

PMID:  Gut. 2005 Feb ;54(2):193-200. PMID: 15647180 Abstract Title:  Apple polyphenol extracts prevent damage to human gastric epithelial cells in vitro and to rat gastric mucosa in vivo. Abstract:  BACKGROUND: Fresh fruit and vegetables exert multiple biological effects on the gastrointestinal mucosa.AIM: To assess whether apple extracts counteract oxidative or indomethacin induced damage to gastric …

Increasing exposure to smartphones can have a negative impact on ocular health in adolescents.

PMID:  Ophthalmic Epidemiol. 2016 08 ;23(4):269-76. Epub 2016 Jun 2. PMID: 27254040 Abstract Title:  Association between Exposure to Smartphones and Ocular Health in Adolescents. Abstract:  PURPOSE: Smartphone use has dramatically increased in recent years. Smartphones may have adverse health effects, particularly on the eyes, because users stare at the screen for a much longer time …

Annurca apple-rich diet restores long-term potentiation and induces behavioral modifications in aged rats.

PMID:  Exp Neurol. 2006 Jun ;199(2):354-61. Epub 2006 Feb 9. PMID: 16480716 Abstract Title:  Annurca apple-rich diet restores long-term potentiation and induces behavioral modifications in aged rats. Abstract:  The impairment of brain functions during aging could be prevented by an increase in antioxidative defenses. In fact, dietary manipulation with antioxidants or with antioxidant-rich extracts from …

Phenolic composition and antimicrobial and antiquorum sensing activity of an ethanolic extract of peels from the apple cultivar Annurca.

PMID:  J Med Food. 2011 Sep ;14(9):957-63. Epub 2011 Apr 10. PMID: 21476926 Abstract Title:  Phenolic composition and antimicrobial and antiquorum sensing activity of an ethanolic extract of peels from the apple cultivar Annurca. Abstract:  This study investigated the phenolic composition and antioxidant capacity of an ethanolic extract from the peel of the Annurca (Malus …

A reappraisal of traditional apple cultivars from Southern Italy as a rich source of phenols with superior antioxidant activity.

PMID:  Food Chem. 2013 Oct 15 ;140(4):672-9. Epub 2013 Mar 14. PMID: 23692752 Abstract Title:  A reappraisal of traditional apple cultivars from Southern Italy as a rich source of phenols with superior antioxidant activity. Abstract:  Few literature data are available on the nutraceutical properties of little widespread local apple cultivars. Such lack of information prevents …

Nutraceutical potential of polyphenolic fractions from Annurca apple.

PMID:  Food Chem. 2013 Oct 15 ;140(4):614-22. Epub 2012 Nov 12. PMID: 23692744 Abstract Title:  Nutraceutical potential of polyphenolic fractions from Annurca apple (M. pumila Miller cv Annurca). Abstract:  The capacities of polyphenolic extracts from Annurca apple peel and flesh to inhibit the glucose and cholesterol uptake by HepG2 cells were evaluated, and compared with …

Annurca apple as a functional food for the contribution to a healthy balance of plasma cholesterol levels.

PMID:  J Sci Food Agric. 2017 May ;97(7):2107-2115. Epub 2016 Sep 23. PMID: 27571713 Abstract Title:  Annurca (Malus pumila Miller cv. Annurca) apple as a functional food for the contribution to a healthy balance of plasma cholesterol levels: results of a randomized clinical trial. Abstract:  BACKGROUND: Recent human studies have evaluated the effect of daily …

Phenolic compounds present in fruit extracts of Malus spp. show antioxidative and pro-apoptotic effects on human gastric cancer cell lines.

PMID:  J Food Biochem. 2019 Sep 1:e13028. Epub 2019 Sep 1. PMID: 31475373 Abstract Title:  Phenolic compounds present in fruit extracts of Malus spp. show antioxidative and pro-apoptotic effects on human gastric cancer cell lines. Abstract:  The study aims to analyze the phenolic compounds in Malus spp. and evaluate their antioxidant and pro-apoptotic effects in …

Lactofermented Annurca apple puree as a functional food indicated for the control of plasma lipid and oxidative amine levels.

PMID:  Nutrients. 2019 Jan 9 ;11(1). Epub 2019 Jan 9. PMID: 30634393 Abstract Title:  Lactofermented Annurca Apple Puree as a Functional Food Indicated for the Control of Plasma Lipid and Oxidative Amine Levels: Results from a Randomised Clinical Trial. Abstract:  Atherosclerotic cardiovascular diseases are preferential targets of healthy diet and preventive medicine partially through strategies …

Annurca apple polyphenol extract selectively kills MDA-MB-231 cells.

PMID:  Sci Rep. 2019 Sep 10 ;9(1):13045. Epub 2019 Sep 10. PMID: 31506575 Abstract Title:  Annurca apple polyphenol extract selectively kills MDA-MB-231 cells through ROS generation, sustained JNK activation and cell growth and survival inhibition. Abstract:  Polyphenols represent the most studied class of nutraceuticals that can be therapeutics for a large spectrum of diseases, including …

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