Apple phlorizin attenuates oxidative stress in Drosophila melanogaster.

PMID:  J Food Biochem. 2019 Mar ;43(3):e12744. Epub 2018 Dec 13. PMID: 31353567 Abstract Title:  Apple phlorizin attenuates oxidative stress in Drosophila melanogaster. Abstract:  Apple phlorizin has a lot of applications owing to its antioxidant and hepatoprotective properties. This study explored the antioxidant effects and life span-prolonging activity of apple phlorizin in Drosophila melanogaster. Treatment …

Protective effect of apple phlorizin on hydrogen peroxide-induced cell damage in HepG2 cells.

PMID:  J Food Biochem. 2019 Sep 12:e13052. Epub 2019 Sep 12. PMID: 31515822 Abstract Title:  Protective effect of apple phlorizin on hydrogen peroxide-induced cell damage in HepG2 cells. Abstract:  Apple phlorizin has many biological activities, such as antioxidant and liver protection. The present study aimed to evaluate the roles of apple phlorizin against hydrogen peroxide …

Fenugreek seed extract ameliorates cognitive deficits in streptozotocin-induced diabetic rats.

PMID:  J Basic Clin Physiol Pharmacol. 2019 Jul 20 ;30(4). Epub 2019 Jul 20. PMID: 31326961 Abstract Title:  Fenugreek seed extract ameliorates cognitive deficits in streptozotocin-induced diabetic rats. Abstract:  Background Natural medicinal plants have been the focus of current research for developing neuroprotective agents to be used in the diabetes-linked cognitive dysfunction. Trigonella foenum-graecum seeds …

Dose-dependent effects of fenugreek seed extract on the biochemical and haematological parameters in high-fat diet-fed rats.

PMID:  J Taibah Univ Med Sci. 2019 Aug ;14(4):383-389. Epub 2019 Jul 17. PMID: 31488972 Abstract Title:  Dose-dependent effects of fenugreek seed extract on the biochemical and haematological parameters in high-fat diet-fed rats. Abstract:  Objective: The present study was carried out to assess the effects of fenugreek seed extract on various biochemical and haematological parameters …

Attenuation of diabetic nephropathy by dietary fenugreek and onion.

PMID:  Nutrition. 2019 Jul 1 ;67-68:110543. Epub 2019 Jul 1. PMID: 31408826 Abstract Title:  Attenuation of diabetic nephropathy by dietary fenugreek (Trigonella foenum-graecum) seeds and onion (Allium cepa) via suppression of glucose transporters and renin-angiotensin system. Abstract:  OBJECTIVES: The aim of this study was to determine the effects of dietary fenugreek (Trigonella foenum-graecum) seeds and …

Allium vegetables for possible future of cancer treatment.

PMID:  Phytother Res. 2019 Aug 29. Epub 2019 Aug 29. PMID: 31464060 Abstract Title:  Allium vegetables for possible future of cancer treatment. Abstract:  Natural resources such as plants are an upright curing option in treating cancers and reducing the side effects of current therapeutic modalities. Allium genus vegetables are of the most interesting herbs in …

Tulsi has the potential to be developed into an antimicrobial agent against cariogenic bacteria, specifically S. mutans.

PMID:  J Indian Soc Pedod Prev Dent. 2019 Jan-Mar;37(1):87-91. PMID: 30804313 Abstract Title:  Estimation of salivary pH and viability ofon chewing of Tulsi leaves in children. Abstract:  Background: The current concepts of dental caries focus on cariogenic bacteria such as Streptococcus mutans fermenting carbohydrates to form organic acids, which cause a drop in pH, resulting …

These results are the first to highlight the beneficial role and relevant mechanisms of Isoliquiritigenin in LPS-induced acute lung injury.

PMID:  Front Immunol. 2017 ;8:1518. Epub 2017 Nov 9. PMID: 29163554 Abstract Title:  Isoliquiritigenin Activates Nuclear Factor Erythroid-2 Related Factor 2 to Suppress the NOD-Like Receptor Protein 3 Inflammasome and Inhibits the NF-κB Pathway in Macrophages and in Acute Lung Injury. Abstract:  Among the cellular response mechanisms, the nuclear factor erythroid-2 related factor 2 (Nrf2) …

Isoliquiritigenin protects against sepsis-induced lung and liver injury by reducing inflammatory responses.

PMID:  Biochem Biophys Res Commun. 2018 02 5 ;496(2):245-252. Epub 2017 Nov 24. PMID: 29180018 Abstract Title:  Isoliquiritigenin protects against sepsis-induced lung and liver injury by reducing inflammatory responses. Abstract:  Sepsis, one of the most fatal diseases worldwide, often leads to multiple organ failure, mainly due to uncontrolled inflammatory responses. Despite accumulating knowledge obtained in …

Isoliquiritigenin inhibits the proliferation and induces the differentiation of human glioma stem cells.

PMID:  Oncol Rep. 2018 Feb ;39(2):687-694. Epub 2017 Dec 13. PMID: 29251326 Abstract Title:  Isoliquiritigenin inhibits the proliferation and induces the differentiation of human glioma stem cells. Abstract:  Glioma stem cells (GSCs) have been proven to be resistant to various therapeutic strategies, such as temozolomide chemotherapy and radiotherapy, leading to glioma recurrence. Isoliquiritigenin (ISL), a …

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