PMID: Cell Physiol Biochem. 2018 ;46(6):2517-2531. Epub 2018 May 5. PMID: 29742507 Abstract Title: Cyanidin Curtails Renal Cell Carcinoma Tumorigenesis. Abstract: BACKGROUND/AIMS: Cyanidin is an anthocyanin found in many foods. Although its variable antioxidant levels are well-documented, little is known about its effects on renal cell carcinoma (RCC) tumorigenesis. This study, therefore, investigated the effects …
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Liquiritigenin reduces blood glucose level and bone adverse effects in hyperglycemia.
PMID: Nutrients. 2019 May 9 ;11(5). Epub 2019 May 9. PMID: 31075971 Abstract Title: Liquiritigenin Reduces Blood Glucose Level and Bone Adverse Effects in Hyperglycemic Adult Zebrafish. Abstract: Diabetes mellitus is a metabolic disease characterized by chronic hyperglycemia that induces other pathologies including diabetic retinopathy and bone disease. Adult(zebrafish) represents a powerful model to study …
Liquiritigenin has the potential for effective treatment of liver fibrosis.
PMID: Phytomedicine. 2018 Dec 10 ;62:152780. Epub 2018 Dec 10. PMID: 31121384 Abstract Title: Liquiritigenin inhibits hepatic fibrogenesis and TGF-β1/Smad with Hippo/YAP signal. Abstract: BACKGROUND: Recent reports highlighted the possibility that Yes-associated protein (YAP) and transforming growth factor-β1 (TGF-β1) can act as critical regulators of hepatic stellate cells (HSCs) activation; therefore, it is natural for …
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Liquiritigenin alleviated cyclophosphamide-induced liver sinusoidal endothelial injury and inflammatory injury.
PMID: Eur J Pharmacol. 2019 Aug 5 ;856:172421. Epub 2019 May 25. PMID: 31136760 Abstract Title: The involvement of DAMPs-mediated inflammation in cyclophosphamide-induced liver injury and the protection of liquiritigenin and liquiritin. Abstract: Cyclophosphamide (CPA) is a chemotherapeutic drug widely used in the treatment of breast cancer or leukemia in clinic. However, CPA was reported …
Liquiritigenin inhibits IL-1β-induced inflammation and cartilage matrix degradation in rat chondrocytes.
PMID: Eur J Pharmacol. 2019 Sep 5 ;858:172445. Epub 2019 Jun 15. PMID: 31211985 Abstract Title: Liquiritigenin inhibits IL-1β-induced inflammation and cartilage matrix degradation in rat chondrocytes. Abstract: Osteoarthritis (OA) is an age-related arthropathy which has been considered to be associated with inflammatory damage and cartilage degradation. Liquiritigenin (LG), the main bioactive component of the …
Exploring common culinary herbs and spices as potential anti-quorum sensing agents.
PMID: Nutrients. 2019 Mar 29 ;11(4). Epub 2019 Mar 29. PMID: 30934945 Abstract Title: Exploring Common Culinary Herbs and Spices as Potential Anti-Quorum Sensing Agents. Abstract: Quorum sensing controls bacterial pathogenesis and virulence; hence, interrupting this system renders pathogenic bacteria non-virulent, and presents a novel treatment for various bacterial infections. In the search for novel …
Anti-inflammatory effect of hydrolyzed celery leaves extract in murine primary splenocyte.
PMID: J Food Biochem. 2019 Sep ;43(9):e12970. Epub 2019 Jul 18. PMID: 31489653 Abstract Title: Anti-inflammatory effect of hydrolyzed celery leaves extract in murine primary splenocyte. Abstract: Apium graveolens (celery) has been used in traditional medicine for the treatment of various ailments. However, its molecular mechanism of action in inflammatory response is unclear. In this …
Apium greaveolens extract treatment can have an analgesic effect in horses affected by chronic osteoarthritic diseases.
PMID: Animals (Basel). 2019 Aug 20 ;9(8). Epub 2019 Aug 20. PMID: 31434330 Abstract Title: Clinical Effects of the Extract of the Seeds of the Indian Celery–In Horses Affected by Chronic Osteoarthritis. Abstract: The extract of the seeds from Indian celery,(CSE), tested in experimental animals (rodents), and in humans affected by chronic osteoarthritic diseases, exhibits …
Effects of aqueous celery extract on lipid parameters of rats fed a high fat diet.
PMID: Planta Med. 1995 Feb ;61(1):18-21. PMID: 7700983 Abstract Title: Effects of aqueous celery (Apium graveolens) extract on lipid parameters of rats fed a high fat diet. Abstract: The antihyperlipidemic property of aqueous celery extract was studied in rats. Two groups of Wistar rats were fed a high fat diet for eight weeks to induce …
An extract of Apium graveolens var. dulce leaves: structure of the major constituent, apiin, and its anti-inflammatory properties.
PMID: J Pharm Pharmacol. 2007 Jun ;59(6):891-7. PMID: 17637182 Abstract Title: An extract of Apium graveolens var. dulce leaves: structure of the major constituent, apiin, and its anti-inflammatory properties. Abstract: Flavonoids, natural compounds widely distributed in the plant kingdom, are reported to affect the inflammatory process and to possess anti-inflammatory as well as immunomodulatory activity …