PMID: Cancer Control. 2019 Jan-Dec;26(1):1073274819871326. PMID: 31452400 Abstract Title: Association of Opioid Use in the Week Before Death Among Patients With Advanced Lung Cancer Having Sepsis. Abstract: Opioid use can induce immunosuppression; however, it is unclear whether opioid use increases infections in patients with advanced cancers. This study assessed the association between opioid use in …
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Morphine promotes the angiogenesis of postoperative recurrent tumors and metastasis of dormant breast cancer cells.
PMID: Pharmacology. 2019 Sep 6:1-11. Epub 2019 Sep 6. PMID: 31494660 Abstract Title: Morphine Promotes the Angiogenesis of Postoperative Recurrent Tumors and Metastasis of Dormant Breast Cancer Cells. Abstract: BACKGROUND: Surgery plays a significant role in the comprehensive treatment of breast cancer, and opioids are often the first-choice analgesics in the perioperative period. However, recent …
Fucoidan affects oral squamous cell carcinoma cell functions in vitro by regulating FLNA-derived circular RNA.
PMID: Ann N Y Acad Sci. 2019 Sep 8. Epub 2019 Sep 8. PMID: 31495936 Abstract Title: Fucoidan affects oral squamous cell carcinoma cell functions in vitro by regulating FLNA-derived circular RNA. Abstract: Oral squamous cell carcinoma (OSCC) is one of the most common cancer types, with a high annual incidence. Although chemotherapy contributes to …
Epigenetic modification and differentiation induction of malignant glioma cells by oligo-fucoidan.
PMID: Mar Drugs. 2019 Sep 8 ;17(9). Epub 2019 Sep 8. PMID: 31500384 Abstract Title: Epigenetic Modification and Differentiation Induction of Malignant Glioma Cells by Oligo-Fucoidan. Abstract: Malignant glioma (MG) is a poor prognostic brain tumor with inevitable recurrence after multimodality treatment. Searching for more effective treatment is urgently needed. Differentiation induction via epigenetic modification …
Xanthohumol could serve as a potential cholesterol-lowering agent.
PMID: J Agric Food Chem. 2019 Sep 17. Epub 2019 Sep 17. PMID: 31525874 Abstract Title: Xanthohumol suppresses NPC1L1 gene expression through down-regulation of HNF-4α and inhibits cholesterol uptake in Caco-2 cells. Abstract: Xanthohumol (Xan) is a prenylated chalcone mainly found in hops, it has been demonstrated to function against hypercholesterolemia, hyperlipidemia, and atherosclerosis. In …
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Xanthohumol induces caspase-dependent degradation of oncoprotein BCR-ABL in K562 cells.
PMID: Antioxidants (Basel). 2019 Sep 16 ;8(9). Epub 2019 Sep 16. PMID: 31527518 Abstract Title: Xanthohumol, a Prenylated Flavonoid from Hops, Induces Caspase-Dependent Degradation of Oncoprotein BCR-ABL in K562 Cells. Abstract: BCR-ABL oncoprotein drives the initiation, promotion, and progression of chronic myelogenous leukemia (CML). Tyrosine kinase inhibitors are the first choice for CML therapy, however, …
Tangeretin inhibits hepatocellular carcinoma proliferation and migration by promoting autophagy-related BECLIN1.
PMID: Cancer Manag Res. 2019 ;11:5231-5242. Epub 2019 Jun 6. PMID: 31239776 Abstract Title: Tangeretin inhibits hepatocellular carcinoma proliferation and migration by promoting autophagy-related BECLIN1. Abstract: Hepatocellular carcinoma (HCC) is a particularly prevalent type of liver cancer and is one of the deadliest malignancies in Asia. Tangeretin is a biological compound extracted from traditional Chinese …
Tangeretin might have potential as a therapeutic agent for the treatment of rheumatoid arthritis.
PMID: Pharmacology. 2019 ;104(3-4):187-195. Epub 2019 Jul 25. PMID: 31344704 Abstract Title: Tangeretin Inhibits Oxidative Stress and Inflammation via Upregulating Nrf-2 Signaling Pathway in Collagen-Induced Arthritic Rats. Abstract: BACKGROUND/AIMS: Tangeretin (TAN), a major phytochemical in tangerine peels and an important Chinese herb, has multiple biological properties, especially antioxidative and anti-inflammatory effects. However, the mechanisms remain …
These results suggest that BPA substitute chemicals are correlated with obesity in contemporary children.
PMID: J Endocr Soc. 2019 Sep 1 ;3(9):1715-1726. Epub 2019 Jul 25. PMID: 31528831 Abstract Title: Urinary Bisphenols and Obesity Prevalence Among U.S. Children and Adolescents. Abstract: Bisphenol A (BPA) has been recognized as an endocrine disrupting chemical and identified as an obesogen. Although once ubiquitous, human exposure to BPA has been declining owing to …
Prenatal exposure to bisphenol A, E and S induces transgenerational effects on male reproductive functions in mice.
PMID: Toxicol Sci. 2019 Sep 18. Epub 2019 Sep 18. PMID: 31532523 Abstract Title: Prenatal exposure to bisphenol A, E and S induces transgenerational effects on male reproductive functions in mice. Abstract: This study was performed to examine the transgenerational effects of bisphenol (BP) A analogues, BPE and BPS on male reproductive functions using mice …
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