PMID: Behav Brain Res. 2016 10 1 ;312:321-32. Epub 2016 Jun 25. PMID: 27353856 Abstract Title: Neuroinflammatory response to experimental stroke is inhibited by eriodictyol. Abstract: BACKGROUND: Cerebral ischemia is a common disease and one of the most common causes of death and disability worldwide. The lack of glucose and oxygen in neuronal tissue leads …
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These results suggest that a combination of green tea and eriodictyol decreases cholesterol levels.
PMID: J Nutr Sci Vitaminol (Tokyo). 2016 ;62(4):249-256. PMID: 27725410 Abstract Title: The Combination of Green Tea Extract and Eriodictyol Inhibited High-Fat/High-Sucrose Diet-Induced Cholesterol Upregulation Is Accompanied by Suppression of Cholesterol Synthesis Enzymes. Abstract: Western diets induce obesity associated with an increased risk of hypercholesterolaemia. Indeed, obesity-induced hypercholesterolaemia is correlated with increased coronary cardiovascular disease …
Eriodictyol can be used as an effective chemopreventive agent against DMH-induced colon carcinogenesis.
PMID: Toxicol Res (Camb). 2017 Sep 1 ;6(5):678-692. Epub 2017 Jun 19. PMID: 30090535 Abstract Title: Effect of eriodictyol on preneoplastic lesions, oxidative stress and bacterial enzymes in 1,2-dimethyl hydrazine-induced colon carcinogenesis. Abstract: Eriodictyol, one of the strong flavonoids extracted from, is known for its antioxidant and anticarcinogenic properties. We estimated the chemopreventive effect of …
Eriodictyol may be used to treat acetaminophen-induced hepatotoxicity.
PMID: Mol Pharm. 2017 09 5 ;14(9):2937-2951. Epub 2017 Jul 17. PMID: 28654297 Abstract Title: Eriodictyol, Not Its Glucuronide Metabolites, Attenuates Acetaminophen-Induced Hepatotoxicity. Abstract: Acetaminophen (APAP) is one of the most commonly used oral analgesics and antipyretics, but hepatotoxicity including liver failure may occur after overdose. The therapeutic options for treating APAP hepatotoxicity are limited. …
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Inhibition of alpha-hemolysin expression by resveratrol attenuates Staphylococcus aureus virulence.
PMID: Microb Pathog. 2019 Feb ;127:85-90. Epub 2018 Nov 20. PMID: 30468853 Abstract Title: Inhibition of alpha-hemolysin expression by resveratrol attenuates Staphylococcus aureus virulence. Abstract: Staphylococcus aureus is an important zoonotic pathogen that causes a variety of life-threatening diseases. The increasing emergence of drug resistance further complicates the treatment of S. aureus infections. The critical …
These results demonstrated that eriodictyol could protect against myocardial ischemia-reperfusion injury.
PMID: Front Pharmacol. 2018 ;9:33. Epub 2018 Jan 30. PMID: 29441020 Abstract Title: Eriodictyol Attenuates Myocardial Ischemia-Reperfusion Injury through the Activation of JAK2. Abstract: Myocardial ischemia-reperfusion (I/R) injury remains the leading risk factor of disability and mortality worldwide. In this study, the myocardial protective effect of eriodictyol (EDT) and the underlying mechanism in anmodel of …
Eriodictyol protects against Staphylococcus aureus-induced lung cell injury by inhibiting alpha-hemolysin expression.
PMID: World J Microbiol Biotechnol. 2018 Apr 18 ;34(5):64. Epub 2018 Apr 18. PMID: 29671126 Abstract Title: Eriodictyol protects against Staphylococcus aureus-induced lung cell injury by inhibiting alpha-hemolysin expression. Abstract: Staphylococcus aureus (S. aureus) is a common pathogenic bacterium that causes various diseases in both humans and animals. With the increased prevalence of methicillin-resistant S. …
Eriodictyol attenuates LPS-induced neuroinflammation, amyloidogenesis, and cognitive impairments.
PMID: J Agric Food Chem. 2018 Oct 3 ;66(39):10205-10214. Epub 2018 Sep 21. PMID: 30208700 Abstract Title: Eriodictyol Attenuates LPS-Induced Neuroinflammation, Amyloidogenesis, and Cognitive Impairments via the Inhibition of NF-κB in Male C57BL/6J Mice and BV2 Microglial Cells. Abstract: Eriodictyol, a natural flavonoid mainly distributed in citrus fruits and peanut, has been well-documented with possession …
Eriodictyol inhibits IL-1β-induced inflammatory response in human osteoarthritis chondrocytes.
PMID: Biomed Pharmacother. 2018 Nov ;107:1128-1134. Epub 2018 Aug 27. PMID: 30257325 Abstract Title: Eriodictyol inhibits IL-1β-induced inflammatory response in human osteoarthritis chondrocytes. Abstract: Osteoarthritis (OA) is a degenerative disease of joints, which is closely associated with cartilage degradation. Eriodictyol, a natural flavonoid compound, has been reported to have anti-inflammatory and anti-osteoclastogenic effects. However, the …
Eriodictyol inhibits high glucose-induced oxidative stress and inflammation in retinal ganglial cells.
PMID: J Cell Biochem. 2019 Apr ;120(4):5644-5651. Epub 2018 Oct 14. PMID: 30317656 Abstract Title: Eriodictyol inhibits high glucose-induced oxidative stress and inflammation in retinal ganglial cells. Abstract: Diabetic retinopathy (DR) is one of the most common microvascular complications of diabetes mellitus and is considered as a leading cause of blindness. Oxidative stress and inflammation …
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