Asiatic acid may be a potential anti-resorptive agent for postmenopausal osteoporosis.

PMID:  Calcif Tissue Int. 2019 Aug 21. Epub 2019 Aug 21. PMID: 31435709 Abstract Title:  Asiatic Acid Attenuates Bone Loss by Regulating Osteoclastic Differentiation. Abstract:  Anti-resorptive agents like bisphosphonates have been widely used for the treatment of postmenopausal osteoporosis. However, their long-term safety and efficacy are still controversial. This study is to examine the effect …

Urolithin A may be adopted as a new therapeutic agent for the treatment of osteoarthritis.

PMID:  Food Funct. 2019 Sep 9. Epub 2019 Sep 9. PMID: 31497826 Abstract Title:  Urolithin A targets the PI3K/Akt/NF-κB pathways and prevents IL-1β-induced inflammatory response in human osteoarthritis: in vitro and in vivo studies. Abstract:  Osteoarthritis (OA) is a degenerative joint disease, whose progression is closely related to the inflammatory environment. Urolithin A (UA), a …

Shikonin can sensitize esophageal cancer cells to paclitaxel-treatment.

PMID:  Oncol Lett. 2019 Sep ;18(3):3195-3201. Epub 2019 Jul 25. PMID: 31452796 Abstract Title:  Shikonin potentiates paclitaxel antitumor efficacy in esophageal cancer cells via the apoptotic pathway. Abstract:  Shikonin is a natural naphthoquinone pigment that can suppress the growth of a number of cancer cell types. Paclitaxel is an antineoplastic chemotherapy drug, which is used …

Low serum vitamin D concentrations are associated with insulin resistance in Mexican children and adolescents.

PMID:  Nutrients. 2019 Sep 5 ;11(9). Epub 2019 Sep 5. PMID: 31491877 Abstract Title:  Low Serum Vitamin D Concentrations Are Associated with Insulin Resistance in Mexican Children and Adolescents. Abstract:  Previous studies in the Mexican adult population have suggested a relationship between low levels of serum concentrations of serum vitamin D with impaired glucose tolerance, …

The present meta-analysis suggests a significant association between low vitamin D levels and recurrent aphthous stomatitis.

PMID:  Oral Dis. 2019 Sep 6. Epub 2019 Sep 6. PMID: 31493304 Abstract Title:  Is vitamin D deficiency a risk factor for recurrent aphthous stomatitis? A systematic review and meta-analysis. Abstract:  OBJECTIVES: A few studies have associated vitamin D deficiency with the occurrence of recurrent aphthous stomatitis (RAS). Hence, the aim of the present systematic …

The association between vitamin D deficiency/lower 25(OH)D levels and sepsis was significant in children and neonates.

PMID:  Clin Nutr. 2019 Aug 27. Epub 2019 Aug 27. PMID: 31495735 Abstract Title:  Association between vitamin D status and sepsis in children: A meta-analysis of observational studies. Abstract:  BACKGROUND: The consequences of vitamin D deficiency regarding sepsis in children remain controversial. We conducted a meta-analysis of studies evaluating the association between vitamin D status …

The beneficial effect of vitamin D supplementation on blood lipids in minorities with type 2 diabetes.

PMID:  Int J Diabetes Clin Res. 2018 ;5(3). Epub 2018 Sep 29. PMID: 31497649 Abstract Title:  The Effect of Vitamin D Supplementation on Blood Lipids in Minorities with Type 2 Diabetes. Abstract:  Introduction: Vitamin D deficiency and type 2 diabetes are common among Hispanics and African Americans in the US. The aim of the study …

Prebiotics may help regulate blood concentrations of ghrelin and CRP in overweight or obese individuals.

PMID:  Nutr Rev. 2019 Sep 5. Epub 2019 Sep 5. PMID: 31504857 Abstract Title:  Prebiotics may reduce serum concentrations of C-reactive protein and ghrelin in overweight and obese adults: a systematic review and meta-analysis. Abstract:  CONTEXT: Biochemical markers correlate positively with the development and severity of obesity, depression, and anxiety, and can be modulated by …

These findings suggest vitamin D predicts tuberculosis disease risk in a dose-dependent manner.

n/a PMID:  PLoS Med. 2019 Sep ;16(9):e1002907. Epub 2019 Sep 11. PMID: 31509529 Abstract Title:  Vitamin D status and risk of incident tuberculosis disease: A nested case-control study, systematic review, and individual-participant data meta-analysis. Abstract:  BACKGROUND: Few studies have evaluated the association between preexisting vitamin D deficiency and incident tuberculosis (TB). We assessed the impact …

Effects of vitamin D deficiency on proliferation and autophagy of ovarian and liver tissues in a model of polycystic ovary syndrome.

PMID:  Biomolecules. 2019 Sep 10 ;9(9). Epub 2019 Sep 10. PMID: 31509973 Abstract Title:  Effects of Vitamin D Deficiency on Proliferation and Autophagy of Ovarian and Liver Tissues in a Rat Model of Polycystic Ovary Syndrome. Abstract:  AIM: We aimed to examine the alterations of the insulin signaling pathway, autophagy, nitrative stress and the effect …

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