PMID: Biofactors. 2019 Sep 12. Epub 2019 Sep 12. PMID: 31512799 Abstract Title: Serum vitamin D concentrations are inversely related to prevalence of metabolic syndrome in Qatari women. Abstract: Hypovitaminosis D has reached epidemic proportions in Qatar. Vitamin D is linked to several cardiometabolic diseases such as metabolic syndrome (MetSyn), diabetes, and atherosclerosis. It is …
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5-hydroxytryptophan attenuates imiquimod-induced psoriasiform dermatitis.
PMID: Exp Dermatol. 2018 11 ;27(11):1273-1279. Epub 2018 Oct 9. PMID: 30221419 Abstract Title: 5-hydroxytryptophan attenuates imiquimod-induced psoriasiform dermatitis probably through inhibition of IL-17A production and keratinocyte activation. Abstract: Psoriasis is a chronic autoimmune disease with keratinocyte activation and lymphocyte infiltration in the skin. Our previous study found that 5-hydroxytryptophan (5(OH)Trp), a tryptophan metabolite, alleviated …
Continue reading “5-hydroxytryptophan attenuates imiquimod-induced psoriasiform dermatitis.”
Arsenic modifies serotonin metabolism through glucuronidation in pancreatic β-cells
PMID: Am J Physiol Endocrinol Metab. 2019 03 1 ;316(3):E464-E474. Epub 2018 Dec 18. PMID: 30562058 Abstract Title: Arsenic modifies serotonin metabolism through glucuronidation in pancreaticβ-cells Abstract: In arsenic-endemic regions of the world, arsenic exposure correlates with diabetes mellitus. Multiple animal models of inorganic arsenic (iAs, as As) exposure have revealed that iAs-induced glucose intolerance …
Rumen-protected 5-hydroxytryptophan improves sheep melatonin synthesis in the pineal gland and intestinal tract.
PMID: Med Sci Monit. 2019 May 15 ;25:3605-3616. Epub 2019 May 15. PMID: 31091223 Abstract Title: Rumen-Protected 5-Hydroxytryptophan Improves Sheep Melatonin Synthesis in the Pineal Gland and Intestinal Tract. Abstract: BACKGROUND Based on the extensive biological effects of melatonin (MLT), it is beneficial to increase the MLT content in the bodies of animals at a …
Different colors of coffee fruit extract have possessed anti-adipogenic and lipolytic properties and may contribute to the anti-obesity effects.
PMID: Kobe J Med Sci. 2018 Oct 15 ;64(3):E84-E92. Epub 2018 Oct 15. PMID: 30666038 Abstract Title: Potential of Coffee Fruit Extract and Quinic Acid on Adipogenesis and Lipolysis in 3T3-L1 Adipocytes. Abstract: This study was to assess the impact of different colors of coffee fruit (green, yellow and red) on adipogenesis and/or lipolysis using …
Green coffee may play a role in protecting muscle injury after the practice of physical exercises.
PMID: J Med Food. 2019 Apr ;22(4):416-420. Epub 2019 Mar 13. PMID: 30864854 Abstract Title: Effects of Green and Ripe Coffee in the Metabolic Profile and Muscle Enzymes in Animals Practicing Physical Exercise. Abstract: Many studies have shown that plants can be therapeutic alternatives in the prevention or treatment of various diseases. Among these, green …
These findings suggest that 2-week ingestion of chlorogenic acid-enriched green coffee bean extract may improve arterial stiffness.
PMID: Int J Food Sci Nutr. 2019 Nov ;70(7):901-908. Epub 2019 Mar 25. PMID: 30907200 Abstract Title: Chlorogenic acid-enriched green coffee bean extract affects arterial stiffness assessed by the cardio-ankle vascular index in healthy men: a pilot study. Abstract: The effect of chlorogenic acid-enriched green coffee bean extract (cGCE) intake on arterial stiffness was investigated …
Green coffee extract could be useful as an adjuvant in combating multidrug resistance strains of Pseudomonas aeruginosa.
PMID: Daru. 2019 Jun ;27(1):35-42. Epub 2019 Jun 12. PMID: 31187452 Abstract Title: Down-regulatory effects of green coffee extract on las I and las R virulence-associated genes in Pseudomonas aeruginosa. Abstract: BACKGROUND: Antibiotic resistant strains of Pseudomonas aeruginosa are the cause of Gram negative nosocomial infections especially among the immunosuppressed patients. The bacteria contains las …
Coffee abundant in chlorogenic acids reduces abdominal fat in overweight adults.
PMID: Nutrients. 2019 Jul 16 ;11(7). Epub 2019 Jul 16. PMID: 31315279 Abstract Title: Coffee Abundant in Chlorogenic Acids Reduces Abdominal Fat in Overweight Adults: A Randomized, Double-Blind, Controlled Trial. Abstract: The components of roasted or green coffee beans that promote abdominal fat reduction are not clear. We investigated the effects of daily consumption of …
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The results of current meta-analysis study support the use of green-coffee extracts supplementation for the improvement of obesity indices.
PMID: Phytomedicine. 2019 Jul 5 ;63:153018. Epub 2019 Jul 5. PMID: 31398662 Abstract Title: The effect of green-coffee extract supplementation on obesity: A systematic review and dose-response meta-analysis of randomized controlled trials. Abstract: BACKGROUND: Given that the most recent systematic review investigating Green-Coffee Extract (GCE) as a weight loss facilitator was nearly a decade ago …