Gadolinium toxicity and treatment.

PMID:  Magn Reson Imaging. 2016 Dec ;34(10):1394-1398. Epub 2016 Sep 28. PMID: 27693607 Abstract Title:  Gadolinium toxicity and treatment. Abstract:  Gadolinium based contrast agents (GBCAs) play an important role in the diagnostic evaluation of many patients. The safety of these agents has been once again questioned after gadolinium deposits were observed and measured in brain …

Gadolinium induced effects on mammalian cell motility, adherence and chromatin structure.

PMID:  Apoptosis. 2017 Feb ;22(2):188-199. PMID: 27770270 Abstract Title:  Gadolinium induced effects on mammalian cell motility, adherence and chromatin structure. Abstract:  The toxicity of gadolinium is reduced by chelating agents that render this heavy metal into contrast complexes used for medical magnetic resonance imaging. However, the dissociation of gadolinium chelates is known to generate Gdions, …

Exposure to sunlight limits diet-induced weight gain, increases liver triglycerides and prevents the early signs of cardiovascular disease in mice.

PMID:  Nutr Metab Cardiovasc Dis. 2019 Jun ;29(6):633-638. Epub 2019 Feb 28. PMID: 30956026 Abstract Title:  Exposure to solar ultraviolet radiation limits diet-induced weight gain, increases liver triglycerides and prevents the early signs of cardiovascular disease in mice. Abstract:  BACKGROUND AND AIMS: Sunlight exposure is associated with a number of health benefits including protecting us …

This study is the only study examining changes in serum and urinary levels of aluminum in 15 infants after a routine 2-month vaccination. The data for the post-vacc measurements are missing.

PMID:  JAMA Pediatr. 2013 Sep ;167(9):870-2. PMID: 23856981 Abstract Title:  Effect of routine vaccination on aluminum and essential element levels in preterm infants. Abstract:  Parenteral feedings containing more than 4 to 5 μg/kg/d of aluminum have been shown to result in neurodevelopmental delay in preterm infants.1 However, an infant at the 2-month checkup receives multiple …

Gadolinium was found to accumulate in the spleen, liver and kidney of animals.

PMID:  Acta Biomater. 2017 01 15 ;48:521-529. Epub 2016 Nov 11. PMID: 27845277 Abstract Title:  Gadolinium accumulation in organs of Sprague-Dawley® rats after implantation of a biodegradable magnesium-gadolinium alloy. Abstract:  : Biodegradable magnesium implants are under investigation because of their promising properties as medical devices. For enhancing the mechanical properties and the degradation resistance, rare …

The CDC’s safety data for aluminum adjuvant safety in infants is based on the pharmacokinetics of a non-adjuvant aluminum compound in one adult male.

PMID:  Vaccine. 2011 Nov 28 ;29(51):9538-43. Epub 2011 Oct 11. PMID: 22001122 Abstract Title:  Updated aluminum pharmacokinetics following infant exposures through diet and vaccination. Abstract:  Aluminum is a ubiquitous element that is released naturally into the environment via volcanic activity and the breakdown of rocks on the earth's surface. Exposure of the general population to …

Crocin attenuates lung inflammation and pulmonary vascular dysfunction in a rat model of bleomycin-induced pulmonary fibrosis.

PMID:  Life Sci. 2019 Aug 26:116794. Epub 2019 Aug 26. PMID: 31465731 Abstract Title:  Crocin attenuates lung inflammation and pulmonary vascular dysfunction in a rat model of bleomycin-induced pulmonary fibrosis. Abstract:  Amongst the various forms of lung injury; pulmonary fibrosis remains the most intricate form with limited therapeutic options to both the patient and the …

Crocin ameliorates chronic obstructive pulmonary disease-induced depression.

PMID:  Eur J Pharmacol. 2019 Sep 3 ;862:172640. Epub 2019 Sep 3. PMID: 31491407 Abstract Title:  Crocin ameliorates chronic obstructive pulmonary disease-induced depression via PI3K/Akt mediated suppression of inflammation. Abstract:  Clinical studies have indicated the co-occurrence of chronic obstructive pulmonary disease (COPD) and psychiatric disorders, for example, comorbid depression. However, the underlying mechanism is rarely …

Does age interfere with gadolinium toxicity and presence in brain and bone tissues?

PMID:  Invest Radiol. 2019 02 ;54(2):61-71. PMID: 30394964 Abstract Title:  Does Age Interfere With Gadolinium Toxicity and Presence in Brain and Bone Tissues?: A Comparative Gadoterate Versus Gadodiamide Study in Juvenile and Adult Rats. Abstract:  OBJECTIVES: The main objective of the study was to assess the effect of age on target tissue total gadolinium (Gd) …

The gadolinium hypothesis for fibromyalgia and unexplained widespread chronic pain.

PMID:  Med Hypotheses. 2019 Aug ;129:109240. Epub 2019 May 20. PMID: 31371082 Abstract Title:  The gadolinium hypothesis for fibromyalgia and unexplained widespread chronic pain. Abstract:  Fibromyalgia (FM) is a chronic, painful, heterogeneous, and common disorder carrying a substantial socio-economical burden. It lacks effective cures and its aetiology is still unknown. There exists evidence for central …

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