PMID: Toxicol Appl Pharmacol. 2019 Jul 15 ;375:32-45. Epub 2019 May 10. PMID: 31082427 Abstract Title: Gadolinium-based contrast agents: Stimulators of myeloid-induced renal fibrosis and major metabolic disruptors. Abstract: Evidence for gadolinium-based contrast agent- (GBCA-) induced disease continues to mount. Risk factors for gadolinium-induced systemic fibrosis are entirely unexplored. Obesity-related renal injury is characterized by …
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Nephrogenic systemic fibrosis manifesting a decade after exposure to gadolinium.
PMID: JAMA Dermatol. 2015 Oct ;151(10):1117-20. PMID: 26017458 Abstract Title: Nephrogenic Systemic Fibrosis Manifesting a Decade After Exposure to Gadolinium. Abstract: IMPORTANCE: Nephrogenic systemic fibrosis (NSF) is a fibrosing skin disorder that develops in patients with kidney failure and has been linked to exposure to gadolinium-containing contrast agents. The time between exposure to gadolinium and …
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Gadolinium deposition was observed especially in bones and in some brain areas: in dentate nucleus and in globus pallidus, even years after administration.
PMID: J Vasc Access. 2017 Mar 28 ;18(Suppl. 2):1-7. Epub 2017 Mar 21. PMID: 28362042 Abstract Title: Gadolinium contrast agents – are they really safe? Abstract: Gadolinium-based contrast agents (GBCA) are used worldwide for enhanced MRI examinations, including heart and vessels. Gadolinium is a highly toxic heavy metal. If used in GBCA it must be …
A literature review of gadolinium-based contrast agents and risk for nephrogenic systemic fibrosis.
PMID: Radiol Technol. 2017 Jul ;88(6):583-589. PMID: 28900045 Abstract Title: GBCAs and Risk for Nephrogenic Systemic Fibrosis: A Literature Review. Abstract: PURPOSE: To examine the risks of using of gadolinium-based contrast agents (GBCAs) in magnetic resonance (MR) imaging and explore strategies to reduce the likeliness of adverse effects in patients who might be at risk …
Self-reported gadolinium toxicity: A survey of patients with chronic symptoms.
PMID: Magn Reson Imaging. 2016 Oct ;34(8):1078-80. Epub 2016 May 19. PMID: 27211256 Abstract Title: Self-reported gadolinium toxicity: A survey of patients with chronic symptoms. Abstract: PURPOSE: This study aims to describe the self-reporting symptoms experienced by individuals with self-reported normal renal function after gadolinium based contrast agent (GBCA) administration.MATERIALS AND METHODS: This HIPAA-compliant, IRB-approved …
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Gadolinium as a new emerging contaminant of aquatic environments.
PMID: Environ Toxicol Chem. 2018 06 ;37(6):1523-1534. Epub 2018 Apr 19. PMID: 29473658 Abstract Title: Gadolinium as a new emerging contaminant of aquatic environments. Abstract: Since the 1980s, gadolinium (Gd)-based contrast agents (GBCAs) have been routinely used in magnetic resonance imaging as stable chelates of the Gdion, without toxic effects. Generally, GBCAs are considered some …
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These results found upregulated inflammation even in the presence of low levels of gadolinium-based contrast agents.
PMID: Contrast Media Mol Imaging. 2018 ;2018:3535769. Epub 2018 Dec 2. PMID: 30627059 Abstract Title: Exposure of Macrophages to Low-Dose Gadolinium-Based Contrast Medium: Impact on Oxidative Stress and Cytokines Production. Abstract: The toxicity of gadolinium-based contrast agents (GBCAs) has drawn a lot of attention. Nephrogenic systemic fibrosis (NSF), a lethal disease related to the use …
Influence of contrast media on blood coagulation.
PMID: Invest Radiol. 1997 May ;32(5):249-59. PMID: 9140744 Abstract Title: Influence of contrast media on blood coagulation. Abstract: RATIONALE AND OBJECTIVES: Contrast agents have been reported to influence the blood clotting system to an extent depending mainly on whether the compounds are ionic or nonionic. The objective of the current series of studies was to …
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The median dentate nucleus maximum standardized uptake value was significantly lower in the subject group than in the control group.
PMID: J Nucl Med Technol. 2017 03 ;45(1):30-33. Epub 2016 Nov 10. PMID: 27834725 Abstract Title: Do Gadolinium-Based Contrast Agents AffectF-FDG PET/CT Uptake in the Dentate Nucleus and the Globus Pallidus? A Pilot Study. Abstract: Gadolinium is toxic and to avoid its deposition in tissues, it must be chemically bonded with nonmetal ions to facilitate …
The presence of the gadolinium-based contrast agent depositions in the brain and symptoms of gadolinium neurotoxicity.
PMID: PLoS One. 2017 ;12(2):e0171704. Epub 2017 Feb 10. PMID: 28187173 Abstract Title: The presence of the gadolinium-based contrast agent depositions in the brain and symptoms of gadolinium neurotoxicity – A systematic review. Abstract: BACKGROUND AND PURPOSE: Gadolinium based contrast agents (GBCAs) are widely used in magnetic resonance imaging, but recently, high signal intensity in …