PMID: Front Pharmacol. 2019 ;10:542. Epub 2019 May 21. PMID: 31164821 Abstract Title: Collateral Sensitivity of Parthenolide via NF-κB and HIF-α Inhibition and Epigenetic Changes in Drug-Resistant Cancer Cell Lines. Abstract: Parthenolide (PT) is a sesquiterpene lactone isolated from. In this study, PT showed varying cytotoxic effects against different solid tumor cell lines. HCT116 (p53) …
Continue reading “Parthenolide could be a novel candidate for cancer treatment.”
PMID: Med Sci Monit. 2019 Jul 8 ;25:5054-5061. Epub 2019 Jul 8. PMID: 31322140 Abstract Title: Parthenolide Inhibits the Proliferation of MDA-T32 Papillary Thyroid Carcinoma Cells in Vitro and in Mouse Tumor Xenografts and Activates Autophagy and Apoptosis by Downregulation of the Mammalian Target of Rapamycin (mTOR)/PI3K/AKT Signaling Pathway. Abstract: BACKGROUNDThis study aimed to examine …
PMID: Curr Med Chem. 2019 Aug 16. Epub 2019 Aug 16. PMID: 31419929 Abstract Title: Parthenolide and Its Analogues: A New Potential Strategy for the Treatment of Triple-Negative Breast Tumors. Abstract: Triple negative breast cancers (TNBC) are heterogeneous and aggressive pathologies, with distinct morphological and clinical characteristics associated with their genetic diversity, epigenetics, transcriptional changes …
PMID: Intest Res. 2019 Aug 23. Epub 2019 Aug 23. PMID: 31426622 Abstract Title: Parthenolide inhibits transforming growth factorβ1-induced epithelial-mesenchymal transition in colorectal cancer cells. Abstract: Background/Aims: Transforming growth factor-β1 (TGF-β1) induction of epithelial-mesenchymal transition (EMT) is one of the mechanisms by which colorectal cancer (CRC) cells acquire migratory and invasive capacities, and subsequently metastasize. …
PMID: Phytother Res. 2019 Sep 9. Epub 2019 Sep 9. PMID: 31497910 Abstract Title: Parthenolide ameliorates intracerebral hemorrhage-induced brain injury in rats. Abstract: Neuroinflammation and oxidative stress are key contributors to intracranial hemorrhage (ICH)-induced brain injury. Parthenolide (PN) is a sesquiterpene lactone that has been observed to have antioxidative, anti-inflammatory, and neuroprotective potentials. However, the …
Continue reading “Parthenolide ameliorates intracerebral hemorrhage-induced brain injury in rats.”
PMID: Int J Pharm. 2019 Aug 26 ;570:118644. Epub 2019 Aug 26. PMID: 31465837 Abstract Title: Colon-specific microspheres loaded with puerarin reduce tumorigenesis and metastasis in colitis-associated colorectal cancer. Abstract: Colitis-associated colorectal cancer (CAC) is a common malignancy that develops in chronically inflamed mucosa and is usually accompanied by metastases at other sites. Puerarin, a …
PMID: Molecules. 2019 May 4 ;24(9). Epub 2019 May 4. PMID: 31060218 Abstract Title: Extracts from Cell Suspension Cultures of Strawberry (Duch): Cytotoxic Effects on Human Cancer Cells. Abstract: Natural compounds are emerging as agents for the treatment of malignant diseases. We previously showed that extracts from in vitro cell suspension cultures of strawberry reduced …
This article is copyrighted by GreenMedInfo LLC, 2019Visit our Re-post guidelines Don’t California my [Insert State Here]: The egregious injustice of SB276 and its trailer bill, which solidified sweeping vaccine legislation into law, was enacted under the false pretenses of fraudulent exemptions, targets medically fragile children, and will usher in an age of medical tyranny …
PMID: iScience. 2019 Aug 16 ;19:676-690. Epub 2019 Aug 16. PMID: 31472342 Abstract Title: Blueberry Extract Improves Obesity through Regulation of the Gut Microbiota and Bile Acids via Pathways Involving FXR and TGR5. Abstract: The metabolic improvement effect of blueberries has long been recognized, although its precise mechanism(s) remains obscure. Here, we show that phenolic …
PMID: Curr Alzheimer Res. 2018 02 22 ;15(4):363-380. PMID: 28847284 Abstract Title: Modulation of Inflammation as a Way of Delaying Alzheimer's Disease Progression: The Diet's Role. Abstract: BACKGROUND: Most of the recent reports suggest that inflammatory mediators play a central role in the etiopathogenesis of Alzheimer's disease (AD) and that the conditions leading to a …
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