PMID:
Comp Biochem Physiol C Toxicol Pharmacol. 2019 Aug ;222:145-155. Epub 2019 May 2. PMID: 31055068
Abstract Title:
Acute exposure to chlorpyrifos and glyphosate induces changes in hemolymph biochemical parameters in the crayfish, Astacus leptodactylus (Eschscholtz, 1823).
Abstract:
Acute and subacute toxicity tests for chlorpyrifos and glyphosate were performed on the crayfish, Astacus leptodactylus. The crayfish were divided into a control group and four experimental groups with exposure from 50.18 to 301.11 μg Lof chlorpyrifos for 96 h under semi-static test conditions. In the same experiment, the crayfish were exposed to different concentrations of glyphosate (from 0.0, 8.14 to 13.05 mg L) for 96 h. Mortality was recorded, and the median lethal concentrations (LC) were calculated using probit analysis. The 96 h LCvalues of chlorpyrifos and glyphosate to A. leptodactylus were 49.55 ± 4.66 μg Land 7.83 ± 0.50 mg L, respectively. The results showed that chlorpyrifos was a few hundred times more toxic than glyphosate for the crayfish. Then, the crayfish were exposed to different subacute concentrations of chlorpyrifos (12.5 and 25 μg L) and glyphosate (2 mg Land 4 mg L) for seven days, and their toxicity was evaluated through several hemolymph biochemical parameters. Chlorpyrifos and glyphosate exposure caused a significant (P
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