Electroacupuncture can effectively treat dry eye syndrome by improving the symptoms, increasing tear secretion and extending tear film break-up time.

PMID: 

Curr Eye Res. 2019 Oct 4:1-9. Epub 2019 Oct 4. PMID: 31557061

Abstract Title: 

A Mechanism Study of Electroacupuncture for Dry Eye Syndrome by Targeting Conjunctival Cytokine Expressions.

Abstract: 

: To discuss the immunological mechanism in electroacupuncture (EA) treatment of dry eye syndrome (DES) by targeting the changes in conjunctival cytokine expression profile.: Eligible DES patients were randomized into an EA group (EAG) or an acupuncture group (AG). The ocular surface disease index (OSDI), amount of tear production, and tear film break-up time (BUT) were observed to evaluate the efficacy. Conjunctival cells were collected from both effective and invalid cases to observe the expressions of cytokines by protein microarray. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) were used for functional cluster and signaling pathway analysis of the differentially expressed proteins. Enzyme-linked immunosorbent assay (ELISA) was used to verify the specific differential proteins.: After treatment, OSDI dropped and BUT extended in both groups, and the tear production increased only in the EAG (all

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