PMID:
Evid Based Complement Alternat Med. 2018 ;2018:3063145. Epub 2018 Aug 15. PMID: 30186353
Abstract Title:
Paeonol Ameliorates Ovalbumin-Induced Asthma through the Inhibition of TLR4/NF-B and MAPK Signaling.
Abstract:
Asthma is a chronic inflammatory disease of the airways, with complex signaling pathways involved in its pathogenesis. It was reported that paeonol attenuated airway inflammation of ovalbumin (OVA)-induced mice. Therefore, it is of importance to further investigate the underlying mechanism. BALB/c mice were challenged with OVA for the asthma model, which was validated by the changed levels of IL-4, IFN-, and IgE. The elevation of IL-4 and the decreasing of IFN-were significantly in middle (p
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