PMID:
Drug Chem Toxicol. 2019 Nov 19:1-7. Epub 2019 Nov 19. PMID: 31742468
Abstract Title:
Evaluation of curcuma and ginger mixture ability to prevent ROS production induced by bisphenol S: anstudy.
Abstract:
The use of bisphenol S (BPS) as a substitute of Bisphenol A is increasing in several products and it can be found in different environmental and biological matrices. Its toxicity has been studied at different levels and one of BPS toxic mechanisms at high concentrations seems to be the induction of oxidative stress through the generation of reactive oxygen species (ROS). This study evaluates the ability of a curcuma and ginger (CG) mixture to exert an antioxidant effect on rat hepatocytes treated with BPS. The effects of the mixture were compared to those of a well-known antioxidant (Trolox). Three different BPS concentrations were used in order to verify ROS production. 70 µg/mL and 150 µg/mL of BPS generated a significant ROS increase (