PMID:
J Anim Sci. 2019 Dec 11. Epub 2019 Dec 11. PMID: 31822918
Abstract Title:
Dietary pterostilbene supplementation attenuates intestinal damage and immunological stress of broiler chickens challenged with lipopolysaccharide1.
Abstract:
The present study explored the potential effect of pterostilbene as a prophylactic treatment on the lipopolysaccharide (LPS)-induced intestinal injury of broiler chickens by monitoring changes in mucosal injury indicators, redox status, and inflammatory responses. In total, 192 one-day-old male Ross 308 broiler chicks were randomly divided into four groups. This trial consisted of a 2× 2 factorial design with a diet factor (supplemented with 0 or 400 mg/kg pterostilbene from 1 to 22 days of age) and a stress factor (intraperitoneally injected with saline or LPS at 5.0 mg/kg body weight at 21 days of age). The results showed that LPS challenge induced a decrease in body weight gain (P
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