These findings suggest that particular Echinacea preparations have significant beneficial effects on anxiety in humans.

PMID: 

Phytother Res. 2019 Dec 25. Epub 2019 Dec 25. PMID: 31876052

Abstract Title: 

Double-blind placebo controlled trial of the anxiolytic effects of a standardized Echinacea extract.

Abstract: 

Earlier studies suggested that specific Echinacea preparations might decrease anxiety. To further study the issue, we performed a double blind, placebo controlled trial with a standardized Echinacea angustifolia root extract. Participants were volunteers scoring above 45 points on the state or on the trait subscale of the State Trait Anxiety Inventory (STAI). They were treated with 40 mg Echinacea or with placebo tablets twice daily for 7 days followed by a 3 week-long washout period. Participants were also administered the Beck Depression Inventory (BDI) and the Perceived Stress Scale (PSS). In the Echinacea group, state anxiety scores decreased by approximately 11 points by the end of the treatment period, whereas the decrease was around 3-points in the placebo group (p

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