There is an increase in adverse cardiorespiratory events following the first dose of DTP-IPV-Hib in preterm infants.

PMID: 

BMC Pediatr. 2006 Jun 19 ;6:20. Epub 2006 Jun 19. PMID: 16784533

Abstract Title: 

Frequency of apnea, bradycardia, and desaturations following first diphtheria-tetanus-pertussis-inactivated polio-Haemophilus influenzae type B immunization in hospitalized preterm infants.

Abstract: 

BACKGROUND: Adverse cardiorespiratory events including apnea, bradycardia, and desaturations have been described following administration of the first diphtheria-tetanus-pertussis-inactivated polio-Haemophilus influenzae type B (DTP-IPV-Hib) immunization to preterm infants. The effect of the recent substitution of acellular pertussis vaccine for whole cell pertussis vaccine on the frequency of these events requires further study.METHODS: Infants with gestational age of

read more