PMID:
J Agric Food Chem. 2020 Jan 12. Epub 2020 Jan 12. PMID: 31927917
Abstract Title:
Pterostilbene Improves Hepatic Lipid Accumulation via the MiR-34a/Sirt1/SREBP-1 Pathway in Fructose-Fed Rats.
Abstract:
High fructose intake promotes hepatic lipid accumulation. Pterostilbene, a natural analogue of resveratrol enriched in diet berries, exhibits hepatoprotective property. Here, we studied the protection by pterostilbene against fructose-induced hepatic lipid accumulation, and explored its possible mechanism. We observed high-expression of microRNA-34a (miR-34a, P