Lactobacillus supplementation during the treatment of Helicobacter pylori infection can effectively improve the eradication rates.

PMID: 

PLoS One. 2019 ;14(10):e0223309. Epub 2019 Oct 2. PMID: 31577828

Abstract Title: 

Efficacy of Lactobacillus-supplemented triple therapy for H. pylori eradication: A meta-analysis of randomized controlled trials.

Abstract: 

AIM: To assess the effect of Lactobacillus supplementation on Helicobacter pylori eradication rates and side effects of the triple therapy.METHODS: PubMed, Embase, Web of Science and Cochrane Library were searched for articles published up to July, 2019. Review Manager 5.3 and Stata 12.0 were used for statistical analyses.RESULTS: The initial database search resulted in 852 articles. Through exclusion and screening, 11 randomized controlled trials involving a total of 724 patients were finally included in this meta-analysis. The H. pylori elimination rate in the Lactobacillus supplement group was significantly higher than that in the control group (RR 1.16, 95% CI 1.08-1.25, P

read more