PMID:
J Clin Psychiatry. 2020 Jan 21 ;81(1). Epub 2020 Jan 21. PMID: 31967748
Abstract Title:
Exercise Intervention for Late-Life Depression: A Meta-Analysis.
Abstract:
OBJECTIVE: To quantify the association between physical exercise intervention (PEI) and reduction in depressive symptoms in older adults.DATA SOURCES: MEDLINE, PsycINFO, and EMBASE were searched from inception through December 2018 with no language restrictions using keywords related to exercise, depression, elderly adults, and randomized controlled trials.STUDY SELECTION: Randomized controlled trials comparing a sedentary control group, with no physically active intervention, to a supervised, moderate-to-vigorous PEI with participants aged≥ 60 years and having a primary outcome of depressive symptoms were included.DATA EXTRACTION: Data on pre- and post-intervention scores on scales measuring depressive symptoms were extracted using a standard form. Random-effects models were used to pool standardized mean differences (Hedges g) in depressive symptoms across studies.DATA SYNTHESIS: Nine studies involving 1,308 participants were included; mean participant age was 82 years. Moderate-to-vigorous PEI was associated with a medium effect size of 0.64 (95% CI, 0.27 to 1.01; z = 3.38; P
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