PMID:
Chin J Physiol. 2018 Oct 31 ;61(5):257-265. PMID: 30384399
Abstract Title:
Anti-Fatigue, Antioxidation, and Anti-Inflammatory Effects of Eucalyptus Oil Aromatherapy in Swimming-Exercised Rats.
Abstract:
Eucalyptus globulus possesses important pharmacological activities, including antioxidant and
anti-inflammatory effects. We investigated the anti-fatigue, antioxidant, and anti-inflammatory
effects of eucalyptus essential oil after swimming exercise using an animal model. Male Sprague–
Dawley rats were administered eucalyptus oil (200 μL/h) daily via inhalation (15 min), and anti-fatigue
effects were assessed following eucalyptus essential oil administration for 2 or 4 weeks when forced
to swim until exhaustion while carrying ~5% body weight-equivalent. To assess antioxidantand
anti-inflammatory effects, control and oil-treated groups were subjected to swimming, which was
intensified from 90 min to 120 min daily over 4 weeks, with non-swimming groups included as
controls. The 2- and 4-week-treated rats increased their swimming-to-exhaustion time by 46 s and
111 s, respectively. Additionally, lactate (LA), creatine kinase (CK), and lactate dehydrogenase
(LDH) activities increased significantly in the non-treated swimming relative to levels observed
in the non-swimming groups (P
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