Primary vaccine failures of the measles vaccine is stalling its “eradication”.

PMID:  J Virol. 2016 06 1 ;90(11):5270-5279. Epub 2016 May 12. PMID: 26984727 Abstract Title:  Generation of a More Immunogenic Measles Vaccine by Increasing Its Hemagglutinin Expression. Abstract:  UNLABELLED: Imported measles virus (MV) outbreaks are maintained by poor vaccine responders and unvaccinated people. A convenient but more immunogenic vaccination strategy would enhance vaccine performance, contributing …

Measles antibodies are higher in the cord blood of unvaccinated, older mothers who were likely infected with the wild measles virus, producing better immunity.

PMID:  Vaccine. 2016 05 23 ;34(24):2750-7. Epub 2016 Apr 22. PMID: 27109563 Abstract Title:  Measles antibodies in cord blood in Portugal: Possible consequences for the recommended age of vaccination. Abstract:  The optimum age to give the first dose of measles vaccine must balance the risks of disease and vaccine failure. Both are influenced by the …

Interferon gamma protects the neonatal brain from measles-induced damage. The adaptive immune response is detrimental in the absence of interferon gamma.

PMID:  J Neuroinflammation. 2016 05 13 ;13(1):107. Epub 2016 May 13. PMID: 27178303 Abstract Title:  Interferon gamma protects neonatal neural stem/progenitor cells during measles virus infection of the brain. Abstract:  BACKGROUND: In the developing brain, self-renewing neural stem/progenitor cells (NSPC) give rise to neuronal and glial lineages. NSPC survival and differentiation can be altered by …

Routine vaccination has skewed measles incidence to the 18-24 year population, a population of which a higher rate of complications is expected.

PMID:  Vaccine. 2016 Apr 19 ;34(18):2092-5. Epub 2016 Mar 14. PMID: 26988260 Abstract Title:  Monitoring the process of measles elimination by serosurveillance data: The Apulian 2012 study. Abstract:  In 2003 Italy adopted the National Plan for Measles and Congenital Rubella Elimination, but some outbreaks of measles are still occurring, as the target coverage rate (≥ …

There has been a resurgence of measles cases in the USA and Europe, including in individuals vaccinated with two doses of the vaccine.

PMID:  Trends Mol Med. 2015 Dec ;21(12):789-801. Epub 2015 Nov 18. PMID: 26602762 Abstract Title:  Variability in Humoral Immunity to Measles Vaccine: New Developments. Abstract:  Despite the existence of an effective measles vaccine, resurgence in measles cases in the USA and across Europe has occurred, including in individuals vaccinated with two doses of the vaccine. …

A case report of gingival enlargement caused by vitamin C deficiency.

PMID:  J Dent Child (Chic). 2018 Jan 15 ;85(1):40-42. PMID: 29663975 Abstract Title:  Gingival Enlargement Caused by Vitamin C Deficiency (Scurvy) in a Boy. Abstract:  Localized gingival enlargement associated with vitamin C deficiency (scurvy) is rarely encountered in the modern era. The purpose of this paper is to report a case of extensive inflammatory gingival …

The results suggest this Tai Chi program may help improve cognitive function and mental well-being for older adults with mild dementia.

PMID:  J Alzheimers Dis. 2019 ;72(3):947-956. PMID: 31743998 Abstract Title:  Effects of a Modified Tai Chi Program on Older People with Mild Dementia: A Randomized Controlled Trial. Abstract:  BACKGROUND: Tai Chi exercise is a non-pharmacological therapy that has received increased attention in recent years. A Tai Chi program has been specifically modified for older people …

Possible effects of proton pump inhibitors on hearing loss development.

PMID:  Biomed Res Int. 2019 ;2019:4853695. Epub 2019 Oct 17. PMID: 31915695 Abstract Title:  Possible Effects of Proton Pump Inhibitors on Hearing Loss Development. Abstract:  Considered safe and often available as over-the-counter (OTC) drugs, proton pump inhibitors (PPI) are one of the most frequently used medicines. Over recent years much research analyzing PPI has been …

Long-term proton pump inhibitor administration caused physiological and microbiota changes in rats.

PMID:  Sci Rep. 2020 Jan 21 ;10(1):866. Epub 2020 Jan 21. PMID: 31964941 Abstract Title:  Long-term Proton Pump Inhibitor Administration Caused Physiological and Microbiota Changes in Rats. Abstract:  Proton pump inhibitors (PPIs) are used for the long-term treatment of gastroesophageal disorders and the non-prescription medicines for acid reflux. However, there is growing concerns about PPI …

Protective effects of astaxanthin supplementation against ultraviolet-induced photoaging.

PMID:  Biomedicines. 2020 Jan 21 ;8(2). Epub 2020 Jan 21. PMID: 31973028 Abstract Title:  Protective Effects of Astaxanthin Supplementation against Ultraviolet-Induced Photoaging in Hairless Mice. Abstract:  Ultraviolet (UV) light induces skin photoaging, which is characterized by thickening, wrinkling, pigmentation, and dryness. Astaxanthin (AST), a ketocarotenoid isolated from, has been extensively studied owing to its possible …

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