PMID: Bioinformation. 2019 ;15(9):657-665. Epub 2019 Oct 13. PMID: 31787815 Abstract Title: Effect of Myristica fragrans extract on total body composition in cafeteria diet induced obese rats. Abstract: It is of interest to evaluate the effect of Myristica fragrans on body composition of cafeteria diet induced obese rats. Thirty rats (150-160g) grouped into 5 and …
Author Archives: Taylor Mercado
Hepatoprotective activity of an herbal composition, MAP, a standardized blend comprising Myristica fragrans, Astragalus membranaceus, and Poria cocos.
PMID: J Med Food. 2016 Oct ;19(10):952-960. Epub 2016 Aug 26. PMID: 27564381 Abstract Title: Hepatoprotective Activity of an Herbal Composition, MAP, a Standardized Blend Comprising Myristica fragrans, Astragalus membranaceus, and Poria cocos. Abstract: Historically, botanicals have been reported to possess good antioxidative activities as demonstrated by their free radical scavenging property rendering their usage …
Bioactivity-guided isolation of anti-inflammatory triterpenoids from the sclerotia of Poria cocos using LPS-stimulated Raw264.7 cells.
PMID: Bioorg Chem. 2017 02 ;70:94-99. Epub 2016 Nov 23. PMID: 27912907 Abstract Title: Bioactivity-guided isolation of anti-inflammatory triterpenoids from the sclerotia of Poria cocos using LPS-stimulated Raw264.7 cells. Abstract: Poria cocos Wolf (Polyporaceae) has been used as a medicinal fungus to treat various diseases since ancient times. This study aimed to investigate the anti-inflammatory …
Effect of Poria cocos hydroethanolic extract on treating adriamycin-induced rat model of nephrotic syndrome.
PMID: Chin J Integr Med. 2017 Dec ;23(12):916-922. Epub 2016 Dec 29. PMID: 28035538 Abstract Title: Effect of Poria cocos hydroethanolic extract on treating adriamycin-induced rat model of nephrotic syndrome. Abstract: OBJECTIVE: To evaluate the effect of Poria cocos (Schw.) Wolf hydroethanolic extract (PHE) against nephrotic syndrome (NS) in rats and to identify the potential …
Cytotoxic constituents from the sclerotia of Poria cocos against human lung adenocarcinoma cells by inducing mitochondrial apoptosis.
PMID: Cells. 2018 Aug 24 ;7(9). Epub 2018 Aug 24. PMID: 30149516 Abstract Title: Cytotoxic Constituents from the Sclerotia ofagainst Human Lung Adenocarcinoma Cells by Inducing Mitochondrial Apoptosis. Abstract: Previous studies have revealed the antitumor potential ofWolf against a broad spectrum of cancers. However, the biological activity ofagainst lung cancer, which is known as the …
Antidepressant and immunosuppressive activities of two polysaccharides from Poria cocos.
PMID: Int J Biol Macromol. 2018 Dec ;120(Pt B):1696-1704. Epub 2018 Sep 26. PMID: 30267822 Abstract Title: Antidepressant and immunosuppressive activities of two polysaccharides from Poria cocos (Schw.) Wolf. Abstract: Pursuit of novel effective antidepressants is an urgent task. Poria cocos (Schw.) Wolf (PCW) is a traditional herb with antidepressant effects. Polysaccharides designated PCWPW and …
Protective effect of lanostane triterpenoids from the sclerotia of Poria cocos Wolf against cisplatin-induced apoptosis in LLC-PK1 cells.
PMID: Bioorg Med Chem Lett. 2017 07 1 ;27(13):2881-2885. Epub 2017 Apr 27. PMID: 28487074 Abstract Title: Protective effect of lanostane triterpenoids from the sclerotia of Poria cocos Wolf against cisplatin-induced apoptosis in LLC-PK1 cells. Abstract: Cisplatin-induced nephrotoxicity is a serious adverse effect that limits the use of cisplatin in cancer patients. In the present …
Hepatoprotective effects exerted by Poria Cocos polysaccharides against acetaminophen-induced liver injury in mice.
PMID: Int J Biol Macromol. 2018 Jul 15 ;114:137-142. Epub 2018 Mar 20. PMID: 29572139 Abstract Title: Hepatoprotective effects exerted by Poria Cocos polysaccharides against acetaminophen-induced liver injury in mice. Abstract: Our study was to investigate the potential pharmacological activity of Poria Cocos polysaccharides (PCP) against acetaminophen (APAP)-induced liver injury in mice. PCP-dosed mice were …
Molecular mechanism of Poria cocos combined with oxaliplatin on the inhibition of epithelial-mesenchymal transition in gastric cancer cells.
PMID: Biomed Pharmacother. 2018 Jun ;102:865-873. Epub 2018 Apr 5. PMID: 29710543 Abstract Title: Molecular mechanism of Poria cocos combined with oxaliplatin on the inhibition of epithelial-mesenchymal transition in gastric cancer cells. Abstract: PURPOSE: Natural product Poria cocos possesses antitumor effect. This study will explore the molecular mechanism of Poria cocos combined with chemotherapy in …
Antihepatotoxic benefits of Poria cocos polysaccharides on acetaminophen-lesioned livers in vivo and in vitro.
PMID: J Cell Biochem. 2019 May ;120(5):7482-7488. Epub 2018 Oct 30. PMID: 30378160 Abstract Title: Antihepatotoxic benefits of Poria cocos polysaccharides on acetaminophen-lesioned livers in vivo and in vitro. Abstract: In our previous study, preliminary data indicates that Poria cocos polysaccharides (PCP) shows beneficial hepatoprotection against acetaminophen (APAP)-induced liver injury in mice. However, biological molecular …
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