PMID: J Surg Res. 2019 Dec 6 ;247:1-7. Epub 2019 Dec 6. PMID: 31816476 Abstract Title: Protective Effect of Epigallocatechin Gallate in Ischemia-Reperfusion Injury of Rat Skeletal Muscle. Abstract: BACKGROUND: Reactive oxygen species-induced cell injury has been considered to be one of the main etiologic factors in ischemia-reperfusion injury (IRI). As a potential antioxidant agent, …
Author Archives: Taylor Mercado
Protective effect of epigallocatechin gallate on endothelial disorders in atherosclerosis.
PMID: J Cardiovasc Pharmacol. 2019 Dec 30. Epub 2019 Dec 30. PMID: 31895874 Abstract Title: Protective effect of epigallocatechin gallate on endothelial disorders in atherosclerosis. Abstract: Healthy vascular endothelial cells regulate vascular tone and permeability, prevent vessel wall inflammation, enhance thromboresistance, and contribute to general vascular health. Furthermore, they perform important functions including the production …
EGCG regulates CTR1 expression through its pro-oxidative property in non-small-cell lung cancer cells.
PMID: J Cell Physiol. 2020 Jan 14. Epub 2020 Jan 14. PMID: 31943177 Abstract Title: EGCG regulates CTR1 expression through its pro-oxidative property in non-small-cell lung cancer cells. Abstract: Copper transporter 1 (CTR1) plays an important role in increasing cisplatin intake. Our previous studies showed that CTR1 expression was upregulated by (-)-epigallocatechin-3-gallate (EGCG), a green tea …
ERα36 is an effective target of epigallocatechin-3-gallate in hepatocellular carcinoma.
PMID: Int J Clin Exp Pathol. 2019 ;12(9):3222-3234. Epub 2019 Sep 1. PMID: 31934166 Abstract Title: ERα36 is an effective target of epigallocatechin-3-gallate in hepatocellular carcinoma. Abstract: Epigallocatechin-3-gallate (EGCG) is a natural product with potential anti-cancer property whose direct target has not been identified. This study intended to investigate ERα36, a new isoform of estrogen …
These findings suggest that tanshinone IIA may protect lung from silica damage.
PMID: Drug Des Devel Ther. 2019 ;13:4275-4290. Epub 2019 Dec 18. PMID: 31908414 Abstract Title: The Protective Role of Tanshinone IIA in Silicosis Rat Model via TGF-β1/Smad Signaling Suppression, NOX4 Inhibition and Nrf2/ARE Signaling Activation. Abstract: Purpose: Silicosis is an occupational disease caused by inhalation of silica and there are no effective drugs to treat …
Continue reading “These findings suggest that tanshinone IIA may protect lung from silica damage.”
Potential ameliorative effects of epigallocatechin-3-gallate against cigarette smoke exposure induced renal and hepatic deficits.
PMID: Ecotoxicol Environ Saf. 2020 Jan 13 ;191:110202. Epub 2020 Jan 13. PMID: 31945511 Abstract Title: Potential ameliorative effects of epigallocatechin-3-gallate against cigarette smoke exposure induced renal and hepatic deficits. Abstract: The environmental pollution caused by cigarette smoke (CS) seriously endangers people's health. Epigallocatechin-3-gallate (EGCG) is the most abundant catechin in green tea. In this …
Tanshinone IIA can effectively improve liver fibrosis and liver function.
PMID: Evid Based Complement Alternat Med. 2019 ;2019:7514046. Epub 2019 Dec 13. PMID: 31915451 Abstract Title: Therapeutic Effect of Tanshinone IIA on Liver Fibrosis and the Possible Mechanism: A Preclinical Meta-Analysis. Abstract: Background: Liver fibrosis is a serious human health problem, and there is a need for specific antifibrosis drugs in the clinic. Tanshinone IIA …
Continue reading “Tanshinone IIA can effectively improve liver fibrosis and liver function.”
Tanshinone IIA reduces oxidized low-density lipoprotein-induced inflammatory responses.
PMID: Int J Clin Exp Pathol. 2019 ;12(10):3791-3798. Epub 2019 Oct 1. PMID: 31933767 Abstract Title: Tanshinone IIA reduces oxidized low-density lipoprotein-induced inflammatory responses by downregulating microRNA-33 in THP-1 macrophages. Abstract: Atherosclerosis is a leading cause of cardiovascular diseases. Oxidized low-density lipoprotein (ox-LDL) is commonly used to construct atherosclerosis cell models. Macrophages-secreted pro-inflammatory factors play …
Potential of coconut oil and medium chain triglycerides in the prevention and treatment of Alzheimer’s disease.
PMID: Mech Ageing Dev. 2020 Jan 14:111209. Epub 2020 Jan 14. PMID: 31953123 Abstract Title: Potential of coconut oil and medium chain triglycerides in the prevention and treatment of Alzheimer's disease. Abstract: Alzheimer's disease (AD) is the most common form of dementia. Currently, there is no effective medication for the prevention or treatment of AD. …
Antibacterial and immunomodulator activities of virgin coconut oil against Staphylococcus aureus.
PMID: Heliyon. 2019 Oct ;5(10):e02612. Epub 2019 Oct 20. PMID: 31673647 Abstract Title: Antibacterial and immunomodulator activities of virgin coconut oil (VCO) against. Abstract: Antibiotics have components to inhibit infections against, but they depend on judicious use to minimize the incidence of resistance forms. Strategies to improve the current situation include research in finding a …
Health Time 