PMID: Phytomedicine. 2019 Dec 23 ;67:153157. Epub 2019 Dec 23. PMID: 31896054 Abstract Title: Fructo-oligosaccharides from Morinda officinalis remodeled gut microbiota and alleviated depression features in a stress rat model. Abstract: BACKGROUND: Inulin-type fructo-oligosaccharides (FOSs) purified from Morinda officinalis How., an effective oral antidepressant for mild to moderate depression, have a largely unknown efficacy and …
Author Archives: Taylor Mercado
Human milk oligosaccharides activate epidermal growth factor receptor and protect against hypoxia-induced injuries.
PMID: J Nutr. 2020 Jan 8. Epub 2020 Jan 8. PMID: 31915826 Abstract Title: Human Milk Oligosaccharides Activate Epidermal Growth Factor Receptor and Protect Against Hypoxia-Induced Injuries in the Mouse Intestinal Epithelium and Caco2 Cells. Abstract: BACKGROUND: Hypoxia-induced intestinal barrier injuries lead to necrotizing enterocolitis (NEC). Although NEC in preterm neonates is preventable by human …
Effects of nondigestible oligosaccharides on obesity.
PMID: Annu Rev Food Sci Technol. 2020 Jan 17. Epub 2020 Jan 17. PMID: 31951486 Abstract Title: Effects of Nondigestible Oligosaccharides on Obesity. Abstract: Obesity is a major public health concern that has almost reached the level of pandemic and is rapidly progressing. Gut microbiota has emerged as a crucial regulator involved in the etiology …
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Oligosaccharides from Morinda officinalis slow the progress of aging mice by regulating the key microbiota-metabolite pairs.
PMID: Evid Based Complement Alternat Med. 2019 ;2019:9306834. Epub 2019 Dec 19. PMID: 31929824 Abstract Title: Oligosaccharides fromSlow the Progress of Aging Mice by Regulating the Key Microbiota-Metabolite Pairs. Abstract: The gut microbiota is considered an important factor in the progression of Alzheimer's disease (AD). Active research on the association between the metabolome and the …
Dietary incorporation of oleic acid and long-chain n-3 fatty acids prevents hyperlipidemia-induced aberrations in the retina.
PMID: Inflammation. 2020 Jan 6. Epub 2020 Jan 6. PMID: 31903511 Abstract Title: Evidence on n-3 Fatty Acids and Oleic Acid Role in Retinal Inflammation and Microvascular Integrity: Insight from a Hyperlipidemic Rat Model. Abstract: Loss of retinal function due to manifestation of chronic inflammation and oxidative stress in hyperglycemia is well addressed. However, the …
Antiproliferative activity of the olive extract rich in polyphenols and modified pectin on bladder cancer cells.
PMID: J Med Food. 2020 Jan 15. Epub 2020 Jan 15. PMID: 31939715 Abstract Title: Antiproliferative Activity of the Olive Extract Rich in Polyphenols and Modified Pectin on Bladder Cancer Cells. Abstract: Bladder cancer (BC) is one of the most common human cancers. There is an interest in controlling and treating BC and other types …
Citrus flavonoids suppress IL-5 and ROS through distinct pathways in PMA/ionomycin-induced EL-4 cells.
PMID: Food Funct. 2020 Jan 14. Epub 2020 Jan 14. PMID: 31932824 Abstract Title: Citrus flavonoids suppress IL-5 and ROS through distinct pathways in PMA/ionomycin-induced EL-4 cells. Abstract: Interleukin-5 (IL-5) strongly initiates the asthmatic inflammatory response, which affects 300 million patients with asthma annually worldwide, through oxidative stress generation. Citrus flavonoids have beneficial properties, such …
Selective effects of ginseng pectins on galectin-3-mediated T cell activation and apoptosis.
PMID: Carbohydr Polym. 2019 Sep 1 ;219:121-129. Epub 2019 May 8. PMID: 31151509 Abstract Title: Selective effects of ginseng pectins on galectin-3-mediated T cell activation and apoptosis. Abstract: Galectin-3 (Gal-3) can induce T-cell activation and apoptosis and plays a role in tumor immune tolerance. Here, we demonstrate that ginseng pectins selectively inhibit Gal-3-induced T-cell apoptosis, …
Modified citrus pectin targets galectin-3-induced STAT3 activation and synergize paclitaxel cytotoxic effect on ovarian cancer spheroids.
PMID: Cancer Med. 2019 Aug ;8(9):4315-4329. Epub 2019 Jun 13. PMID: 31197964 Abstract Title: Pectasol-C Modified Citrus Pectin targets Galectin-3-induced STAT3 activation and synergize paclitaxel cytotoxic effect on ovarian cancer spheroids. Abstract: Here we sought to determine the relationship between STAT3 activity and Galectin-3 (Gal-3) and to investigate the cytotoxic effect of PectaSol-C Modified Citrus …
Dietary fiber pectin ameliorates experimental colitis in a neutral sugar side chain-dependent manner.
PMID: Front Immunol. 2019 ;10:2979. Epub 2019 Dec 19. PMID: 31921214 Abstract Title: Dietary Fiber Pectin Ameliorates Experimental Colitis in a Neutral Sugar Side Chain-Dependent Manner. Abstract: Dietary fiber, with intake of soluble fibers in particular, has been reported to lower the risk for developing inflammatory bowel diseases (IBD). This is at least partly attributable …
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