PMID: Colloids Surf B Biointerfaces. 2019 Oct 23 ;186:110603. Epub 2019 Oct 23. PMID: 31846892 Abstract Title: Improved chemotherapeutic efficacy against resistant human breast cancer cells with co-delivery of Docetaxel and Thymoquinone by Chitosan grafted lipid nanocapsules: Formulation optimization, in vitro and in vivo studies. Abstract: In recent years, multi-targeted chemotherapeutic combinations have received considerable …
Author Archives: Taylor Mercado
Thymoquinone-containing novel polyherbal formulation was beneficial against cisplatin-induced hepatorenal toxicity.
PMID: J Food Biochem. 2019 Dec 26:e13131. Epub 2019 Dec 26. PMID: 31876968 Abstract Title: Pharmacological studies on the efficacy of a thymoquinone-containing novel polyherbal formulation against cisplatin-induced hepatorenal toxicity in rats. Abstract: The aim of this study was to investigate the protective effect of a novel polyherbal formulation against cisplatin-induced hepatorenal toxicity in six …
Thymoquinone and pentoxifylline enhance the chemotherapeutic effect of cisplatin by targeting Notch signaling pathway in mice.
PMID: Life Sci. 2020 Jan 14:117299. Epub 2020 Jan 14. PMID: 31953157 Abstract Title: Thymoquinone and pentoxifylline enhance the chemotherapeutic effect of cisplatin by targeting Notch signaling pathway in mice. Abstract: AIMS: Notch signaling is highly implicated in several cancers and chemoresistance. Therefore, Notch-targeted therapies might be beneficial in enhancing chemotherapeutic effect and cancer regression. …
Effects of thymoquinone on small-molecule metabolites in a rat model of cerebral ischemia reperfusion injury.
PMID: Metabolites. 2020 Jan 7 ;10(1). Epub 2020 Jan 7. PMID: 31936061 Abstract Title: Effects of Thymoquinone on Small-Molecule Metabolites in a Rat Model of Cerebral Ischemia Reperfusion Injury Assessed using MALDI-MSI. Abstract: Thymoquinone is one of the main components present in Nigella sativa seeds and is known to have various biological functions in inflammation, …
Increased blood lead level induces oxidative stress and alters the antioxidant status of spray painters.
PMID: J Basic Clin Physiol Pharmacol. 2020 Jan 11. Epub 2020 Jan 11. PMID: 31926081 Abstract Title: Increased blood lead level induces oxidative stress and alters the antioxidant status of spray painters. Abstract: Background The aim of this study was to know the present scenario of blood lead level and its effect on serum lipid …
Vitamin C could be a potential fertility enhancer against lifestyle stressors.
PMID: Reprod Biol Endocrinol. 2020 Jan 11 ;18(1):2. Epub 2020 Jan 11. PMID: 31926565 Abstract Title: Attenuation of sleep deprivation dependent deterioration in male fertility parameters by vitamin C. Abstract: PURPOSE: Male fertility is multifaceted and its integrity is as well multifactorial. Normal spermatogenesis is dependent on competent testicular function; namely normal anatomy, histology, physiology …
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This review summarizes recent knowledge about the impact of common nutraceuticals for the regulation of blood pressure.
PMID: Food Res Int. 2020 Feb ;128:108749. Epub 2019 Nov 7. PMID: 31955788 Abstract Title: The role of nutraceuticals in prevention and treatment of hypertension: An updated review of the literature. Abstract: Hypertension (HTN) is a worldwide epidemic in both developed and developing countries. It is one of the leading causes of major health problems …
Lung anti-oxidant depletion: a predictive indicator of cellular stress induced by ambient fine particles.
PMID: Environ Sci Technol. 2020 Jan 21. Epub 2020 Jan 21. PMID: 31961142 Abstract Title: Lung anti-oxidant depletion: a predictive indicator of cellular stress induced by ambient fine particles. Abstract: Regulations on ambient particulate matter (PM) are becoming more stringent due to adverse health effects arising from PM exposure. PM-induced oxidant production is a key …
Ethanolic extract of papaya leaf could be formulated as a potent natural insecticide to control populations of German cockroach.
PMID: Pak J Biol Sci. 2020 Jan ;23(2):126-131. PMID: 31944071 Abstract Title: Potency of Papaya Leaf (Carica papayaL.) as Toxicant and Repellent against German Cockroach (Blattella germanicaL.). Abstract: BACKGROUND AND OBJECTIVE: Papaya leaves have the potency to be developed as alternative insecticide to control the German cockroaches that have been resistant to synthetic insecticides. This …
Ferulic acid attenuates oxidative DNA damage and inflammatory responses in microglia induced by benzo(a)pyrene.
PMID: Int Immunopharmacol. 2019 Dec ;77:105980. Epub 2019 Nov 4. PMID: 31699670 Abstract Title: Ferulic acid attenuates oxidative DNA damage and inflammatory responses in microglia induced by benzo(a)pyrene. Abstract: Over-activation of microglia disrupts the physiological homeostasis of the brain, and induces inflammatory response and other processes which are implicated in neurodegenerative diseases. Therefore, theoretically, suppression …
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