This study concludes no vaccine-related adverse events, however, it’s not possible to delineate causality with concomitant administration of vaccines.

PMID:  Pediatr Infect Dis J. 2015 Jun ;34(6):627-34. PMID: 25831420 Abstract Title:  An open-label, randomized study of a 9-valent human papillomavirus vaccine given concomitantly with diphtheria, tetanus, pertussis and poliomyelitis vaccines to healthy adolescents 11-15 years of age. Abstract:  BACKGROUND: A 9-valent human papillomavirus (9vHPV) vaccine has recently been reported to be safe and highly …

Researchers are suggesting persistent calling as a way to improve HPV vaccination.

PMID:  Vaccine. 2015 May 15 ;33(21):2425-31. Epub 2015 Apr 11. PMID: 25869895 Abstract Title:  Actions improving HPV vaccination uptake – Results from a national survey in Italy. Abstract:  BACKGROUND: In Italy, HPV vaccination is offered to 11-year-old girls since 2007. In 2012 coverage was 69%. Strategies for offering and promoting HPV vaccination and coverage rates …

Models of the effect and cost-effectiveness of human papillomavirus (HPV) vaccine were developed before HPV vaccines were approved for use in the United States.

PMID:  Emerg Infect Dis. 2015 Jun ;21(6):960-8. PMID: 25989525 Abstract Title:  Cost-effectiveness of Chlamydia vaccination programs for young women. Abstract:  We explored potential cost-effectiveness of a chlamydia vaccine for young women in the United States by using a compartmental heterosexual transmission model. We tracked health outcomes (acute infections and sequelae measured in quality-adjusted life-years [QALYs]) …

The estimation of adverse event incidence is hard to predict due to under-reporting of HPV adverse events as a result of biases and therefore requires larger scale studies.

PMID:  Pharmacogenomics J. 2015 Jun ;15(3):284-7. Epub 2014 Oct 7. PMID: 25287071 Abstract Title:  The first steps towards the era of personalised vaccinology: predicting adverse reactions. Abstract:  Until now, the occurrence of adverse reactions among individuals inoculated with identical vaccines has been ascribed to unpredictable stochastic processes. Recent advances in pharmacogenomics indicate that some features …

90% of HPV infections are cleared within 2 years.

PMID:  Clin Vaccine Immunol. 2015 Aug ;22(8):850-7. Epub 2015 Jun 10. PMID: 26063238 Abstract Title:  Early Defensive Mechanisms against Human Papillomavirus Infection. Abstract:  Cervical cancer is the fourth most common cancer in women and is almost exclusively caused by human papillomavirus (HPV) infection. HPV is also frequently associated with other cancers arising from mucosal epithelium, …

Because of the slow natural history of HPV oncogenesis, the effect of vaccination on invasive cancers will not be evident for decades.

PMID:  Emerg Infect Dis. 2015 Sep ;21(9):1557-61. PMID: 26291379 Abstract Title:  Monitoring Effect of Human Papillomavirus Vaccines in US Population, Emerging Infections Program, 2008-2012. Abstract:  In 2007, five Emerging Infections Program (EIP) sites were funded to determine the feasibility of establishing a population-based surveillance system for monitoring the effect of human papillomavirus (HPV) vaccine on …

60% of general practitioners in this French survey considered that not enough is known about the HPV vaccine’s risks. Those who did not feel comfortable recommending the vaccine cited unfavorable perceptions about its risk-benefit balance.

PMID:  Vaccine. 2016 Feb 3 ;34(6):762-8. Epub 2016 Jan 2. PMID: 26752063 Abstract Title:  General practitioners' attitudes and behaviors toward HPV vaccination: A French national survey. Abstract:  OBJECTIVE: General practitioners (GPs) play a crucial role in human papillomavirus (HPV) vaccine acceptance in France. We sought to study: (1) GPs' perceptions of its risks and efficacy …

The latency period used to observe increased risk of adverse events was not long enough to exclude all serious adverse events.

PMID:  Am J Epidemiol. 2018 06 1 ;187(6):1281. PMID: 29860469 Abstract Title:  Yih et al. Respond to"Moving From Evidence to Impact for Human Papillomavirus Vaccination". Abstract:  [n/a] read more

Receipt of multiple vaccines on the same day makes it difficult to establish causality between vaccines and adverse events.

PMID:  Am J Epidemiol. 2018 06 1 ;187(6):1277-1280. PMID: 29860471 Abstract Title:  Invited Commentary: Moving From Evidence to Impact for Human Papillomavirus Vaccination-The Critical Role of Translation and Communication in Epidemiology. Abstract:  In response to the accompanying article by Yih et al. (Am J Epidemiol. 2018;187(6):1269-1276), we highlight the importance of moving beyond epidemiologic research …

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