Dietary selenium supplementation ameliorates female reproductive efficiency in aging mice.

PMID:  Antioxidants (Basel). 2019 Dec 11 ;8(12). Epub 2019 Dec 11. PMID: 31835711 Abstract Title:  Dietary Selenium Supplementation Ameliorates Female Reproductive Efficiency in Aging Mice. Abstract:  Female reproductive (ovarian) aging is distinctively characterized by a markedly reduced reproductive function due to a remarkable decline in quality and quantity of follicles and oocytes. Selenium (Se) has …

Glycyrrhizin may become a novel cytokine for the therapy of intervertebral disc degeneration in the future.

PMID:  Am J Transl Res. 2019 ;11(8):5105-5113. Epub 2019 Aug 15. PMID: 31497226 Abstract Title:  Glycyrrhizin suppresses inflammation and cell apoptosis by inhibition of HMGB1 via p38/p-JUK signaling pathway in attenuating intervertebral disc degeneration. Abstract:  Intervertebral disc degeneration (IDD) is associated with the nucleus pulposus (NP) cells inflammation and apoptosis. Previous studies have shown that …

Glycyrrhizin mitigates radiation‐induced acute lung injury.

PMID:  J Cell Mol Med. 2020 Jan ;24(1):214-226. Epub 2019 Oct 27. PMID: 31657123 Abstract Title:  Glycyrrhizin mitigates radiation-induced acute lung injury by inhibiting the HMGB1/TLR4 signalling pathway. Abstract:  Radiation-induced lung injury (RILI) is the major complication of thoracic radiation therapy, and no effective treatment is available. This study explored the role of high-mobility group …

Glycyrrhizin prevents hemorrhagic transformation and improves neurological outcome in ischemic stroke with delayed thrombolysis.

PMID:  Transl Stroke Res. 2019 Dec 24. Epub 2019 Dec 24. PMID: 31872339 Abstract Title:  Glycyrrhizin Prevents Hemorrhagic Transformation and Improves Neurological Outcome in Ischemic Stroke with Delayed Thrombolysis Through Targeting Peroxynitrite-Mediated HMGB1 Signaling. Abstract:  Peroxynitrite (ONOO) and high mobility group box 1 protein (HMGB1) are important cytotoxic factors contributing to cerebral ischemia-reperfusion injury. However, …

Selenium alleviates lipopolysaccharide-induced endometritis.

PMID:  Food Funct. 2019 Dec 17. Epub 2019 Dec 17. PMID: 31845693 Abstract Title:  Selenium alleviates lipopolysaccharide-induced endometritis via regulating the recruitment of TLR4 into lipid rafts in mice. Abstract:  Selenium (Se) is an essential trace element for living organisms and plays diverse biological roles. Endometritis is a common reproductive disorder in dairy cows, causing …

Melatonin attenuates nicotine-induced autophagy and neurological changes by decreasing the production of reactive oxygen species.

PMID:  Int J Neurosci. 2019 Nov 26:1-7. Epub 2019 Nov 26. PMID: 31721620 Abstract Title:  Melatonin attenuates nicotine-induced autophagy and neurological changes by decreasing the production of reactive oxygen species. Abstract:  The aim of this study was to explore the mechanism of neurological changes underlying the toxicity of nicotine.Rat pheochromocytoma 12 (PC12) cells and human …

Melatonin reverses depressive and anxiety like-behaviours induced by diabetes.

PMID:  Arch Physiol Biochem. 2019 Nov 15:1-9. Epub 2019 Nov 15. PMID: 31726890 Abstract Title:  Melatonin reverses depressive and anxiety like-behaviours induced by diabetes: involvement of oxidative stress, age, rage and S100B levels in the hippocampus and prefrontal cortex of rats. Abstract:  Diabetes is associated with depression and anxiety symptoms. The current investigation was designed …

Melatonin is a potential target for improving post-harvest preservation of fruits and vegetables.

PMID:  Front Plant Sci. 2019 ;10:1388. Epub 2019 Oct 30. PMID: 31737014 Abstract Title:  Melatonin Is a Potential Target for Improving Post-Harvest Preservation of Fruits and Vegetables. Abstract:  Melatonin is a ubiquitous molecule distributed in nature and not only plays an important role in animals and humans but also has extensive functions in plants, such …

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