PMID: Food Chem Toxicol. 2019 Dec 27 ;136:111076. Epub 2019 Dec 27. PMID: 31883990 Abstract Title: A multiple endpoint approach reveals potential in vitro anticancer properties of thymoquinone in human renal carcinoma cells. Abstract: Thymoquinone (TQ) is a monoterpene isolated from the oil of Nigella sativa seeds. The aim of this work was to evaluate …
Author Archives: Taylor Mercado
The antidiabetic effect of thymoquinone: A systematic review and meta-analysis of animal studies.
PMID: Food Res Int. 2020 Jan ;127:108736. Epub 2019 Oct 15. PMID: 31882078 Abstract Title: The antidiabetic effect of thymoquinone: A systematic review and meta-analysis of animal studies. Abstract: Thymoquinone (2-isopropyl-5-methylbenzo-1, 4-quinone) (TQ) is a quinone derivative with a yellow crystalline appearance, abundantly found in black cumin, Nigella sativa L. TQ has diverse pharmacological properties. …
The reviewed reports confirmed the strong anti-cancer efficacy of thymoquinone.
PMID: Saudi Pharm J. 2019 Dec ;27(8):1113-1126. Epub 2019 Sep 25. PMID: 31885471 Abstract Title: Thymoquinone (2-Isoprpyl-5-methyl-1, 4-benzoquinone) as a chemopreventive/anticancer agent: Chemistry and biological effects. Abstract: Cancer remains the topmost disorders of the mankind and number of cases is unceasingly growing at unprecedented rates. Although the synthetic anti-cancer compounds still hold the largest market …
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Nigella sativa seed oil supplements may decrease the liver enzymes and lipid profiles in the patients with NAFLD.
PMID: J Diabetes Metab Disord. 2019 Dec ;18(2):453-459. Epub 2019 Sep 11. PMID: 31890671 Abstract Title: The effect ofoil on serum levels of inflammatory markers, liver enzymes, lipid profile, insulin and fasting blood sugar in patients with non-alcoholic fatty liver. Abstract: Background: Non-alcoholic fatty liver disease (NAFLD) is one of the metabolic disturbances associated with …
Nigella sativa supplementation may provide additional benefits for the treatment of asthma.
PMID: Am J Emerg Med. 2019 Nov 29. Epub 2019 Nov 29. PMID: 31892440 Abstract Title: The influency of Nigella sativa for asthma control: A meta-analysis. Abstract: INTRODUCTION: The efficacy of Nigella sativa supplementation for asthma control remains controversial. We conduct a systematic review and meta-analysis to explore the influence of Nigella sativa supplementation on …
Tanshinone IIA enhances the inhibitory effect of imatinib on proliferation and motility of acute leukemia cell line TIB‑152.
PMID: Oncol Rep. 2019 Dec 31. Epub 2019 Dec 31. PMID: 31894340 Abstract Title: Tanshinone IIA enhances the inhibitory effect of imatinib on proliferation and motility of acute leukemia cell line TIB‑152 in vivo and in vitro by inhibiting the PI3K/AKT/mTOR signaling pathway. Abstract: Acute lymphoblastic leukemia (ALL) is a malignant hematological disease. Tanshinone IIA (Tan IIA) has …
Nephroprotective effect of herbal extract Eurycoma longifolia on paracetamol-induced nephrotoxicity.
PMID: Evid Based Complement Alternat Med. 2019 ;2019:4916519. Epub 2019 May 13. PMID: 31214269 Abstract Title: Nephroprotective Effect of Herbal Extracton Paracetamol-Induced Nephrotoxicity in Rats. Abstract: Paracetamol (PCM) is a well-known drug widely used for its analgesic and antipyretic properties. PCM is generally considered as safe but overdose of PCM can cause nephrotoxicity. Traditionally, herbs …
Protective effects of fulvotomentosides on cadmium-induced hepatotoxicity.
PMID: Zhongguo Yao Li Xue Bao. 1992 May ;13(3):213-7. PMID: 1442101 Abstract Title: Protective effects of fulvotomentosides on cadmium-induced hepatotoxicity. Abstract: Fulvotomentosides (Ful) is the total saponins of Lonicera fulvotomentosa. In the present study, we examined the effects of Ful on cadmium (CdCl2)-induced acute liver injury in mice. Ful pretreatment (150 mg.kg-1, sc x 3 …
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Toxic acetaminophen exposure induces distal lung ER stress, proinflammatory signalling, and emphysematous changes in the adult murine lung.
PMID: Oxid Med Cell Longev. 2019 ;2019:7595126. Epub 2019 Nov 28. PMID: 31885815 Abstract Title: Toxic Acetaminophen Exposure Induces Distal Lung ER Stress, Proinflammatory Signaling, and Emphysematous Changes in the Adult Murine Lung. Abstract: Clinical studies have demonstrated a strong association between both acute toxic exposure and the repetitive, chronic exposure to acetaminophen (APAP) with …
N-acetylcysteine can protect against polystyrene microplastic induced sperm damage.
PMID: Ecotoxicol Environ Saf. 2019 Dec 30 ;190:110133. Epub 2019 Dec 30. PMID: 31896473 Abstract Title: Exposure to polystyrene microplastics causes reproductive toxicity through oxidative stress and activation of the p38 MAPK signaling pathway. Abstract: Microplastics (MP) are receiving increased attention as a harmful environmental pollutant, however information on the reproduction toxicity of MP in …
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