Supplementation of hesperidin provides protection against redox imbalance induced by hyperlipidemia.

PMID:  Clin Exp Pharmacol Physiol. 2019 Dec 2. Epub 2019 Dec 2. PMID: 31793010 Abstract Title:  Hesperidin attenuates altered redox homeostasis in an experimental hyperlipidemic model of rat. Abstract:  Diets rich in saturated fats, and cholesterol contribute to the incidence of hyperlipidemia. An altered lipid profile is a major factor responsible for the development of …

Hesperidin supplementation can improve metabolic abnormalities and inflammatory status in patients with metabolic syndrome.

PMID:  Eur J Nutr. 2019 Dec 16. Epub 2019 Dec 16. PMID: 31844967 Abstract Title:  The effect of hesperidin supplementation on metabolic profiles in patients with metabolic syndrome: a randomized, double-blind, placebo-controlled clinical trial. Abstract:  PURPOSE: Hesperidin as an antioxidant flavonoid exerts anti-adipogenic, anti-inflammatory, anti-oxidant and anti-hypercholesterolemic effects. Besides, the increasing prevalence of metabolic syndrome …

Protective effects of hesperidin and diosmin against acrylamide-induced liver, kidney, and brain oxidative damage.

PMID:  Environ Sci Pollut Res Int. 2019 Dec ;26(34):35151-35162. Epub 2019 Nov 4. PMID: 31686333 Abstract Title:  Protective effects of hesperidin and diosmin against acrylamide-induced liver, kidney, and brain oxidative damage in rats. Abstract:  Acrylamide (AA) is a heat-induced toxin formed during thermal processing of many commonly consumed foods, including meat products, French fries, potato …

Diosmin ameliorative effects on oxidative stress and fibrosis in paraquat-induced lung injury in mice.

PMID:  Environ Sci Pollut Res Int. 2019 Nov 15. Epub 2019 Nov 15. PMID: 31732951 Abstract Title:  Diosmin ameliorative effects on oxidative stress and fibrosis in paraquat-induced lung injury in mice. Abstract:  Paraquat (PQ) induces pulmonary fibrosis, a progressive lung disorder resulting in severe respiratory failure and death. Increased oxidative stress, inflammatory reactions, and multiple …

Diosmin has a protective effect against lead exposure.

PMID:  Naunyn Schmiedebergs Arch Pharmacol. 2019 Dec 12. Epub 2019 Dec 12. PMID: 31792554 Abstract Title:  The effect of diosmin against lead exposure in rats. Abstract:  In this study, the effect of diosmin against the adverse effects of lead exposure in rats was investigated. Wistar Albino race 40 male rats weighing 150-200 g 2-3 months …

Protective role of diosmin against testosterone propionate-induced prostatic hyperplasia.

PMID:  Hum Exp Toxicol. 2019 Dec 4:960327119889655. Epub 2019 Dec 4. PMID: 31797688 Abstract Title:  Protective role of diosmin against testosterone propionate-induced prostatic hyperplasia in Wistar rats: Plausible role of oxidative stress and inflammation. Abstract:  Benign prostatic hyperplasia (BPH) is an important key health concern for aging men. Polyphenolic compounds have been found to possess …

Phthalate exposure and neurodevelopmental outcomes in early school age children from Poland.

PMID:  Environ Res. 2019 Dec ;179(Pt B):108829. Epub 2019 Oct 18. PMID: 31677502 Abstract Title:  Phthalate exposure and neurodevelopmental outcomes in early school age children from Poland. Abstract:  Some phthalates are known endocrine disrupting chemicals (EDC). They are widely present in the environment thus their impact on children's health is of particular scientific interest. The …

Early-life phthalate exposure was found to be associated with the behavioural characteristics of children.

PMID:  Sci Total Environ. 2020 Jan 10 ;699:134053. Epub 2019 Aug 29. PMID: 31678884 Abstract Title:  Prenatal and childhood phthalate exposure and attention deficit hyperactivity disorder traits in child temperament: A 12-year follow-up birth cohort study. Abstract:  Temperamental tendencies may form the basis of personality development, and specific personality constellations are associated with increased incidences …

Diosmin induces caspase-dependent apoptosis in human glioblastoma cells.

PMID:  An Acad Bras Cienc. 2019 ;91(4):e20191031. Epub 2019 Dec 2. PMID: 31800712 Abstract Title:  Diosmin induces caspase-dependent apoptosis in human glioblastoma cells. Abstract:  Diosmin is a flavone glycoside clinically used as the main component of Daflon for the treatment of venous diseases. Several studies demonstrated that this natural compound can induce apoptosis in different …

Vitamin E and curcumin can alleviate dibutyl phthalate-induced splenic injury.

PMID:  Food Chem Toxicol. 2019 Nov 8:110955. Epub 2019 Nov 8. PMID: 31712109 Abstract Title:  Dibutyl phthalate-mediated oxidative stress induces splenic injury in mice and the attenuating effects of vitamin E and curcumin. Abstract:  Dibutyl phthalate (DBP) is a ubiquitous environmental contaminant that at certain levels can be harmful to human health. Although DBP has …

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