PMID: 

Biochem Biophys Res Commun. 2005 Jun 24 ;332(1):28-32. PMID: 15896294

Abstract Title: 

Decrease in glucose-stimulated insulin secretion following exposure to magnetic fields.

Abstract: 

We evaluated the effects of extremely low frequency magnetic field (ELFMF) on glucose-stimulated insulin secretion from HIT-T15 cells and investigated the mechanisms of these effects. We demonstrated that exposure to ELFMF at 5mT decreased glucose-stimulated insulin secretion by preventing the increases in cellular adenosine 5'-triphosphate/adenosine 5'-diphosphate, membrane depolarization, and cytosolic free calcium ion concentration. The glucose-induced upregulation of insulin mRNA expression was also attenuated by exposure to ELFMF, although cell viability was not affected. These findings demonstrate the potential of exposure to ELFMF for clinical use as a novel inhibitory method of insulin secretion.

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PMID: 

J Microsc Ultrastruct. 2017 Oct-Dec;5(4):177-184. Epub 2017 Sep 14. PMID: 30023252

Abstract Title: 

Skeptical approaches concerning the effect of exposure to electromagnetic fields on brain hormones and enzyme activities.

Abstract: 

This review discusses the effects of various frequencies of electromagnetic fields (EMF) on brain hormones and enzyme activity. In this context, the mechanism underlying the effects of EMF exposure on tissues generally and cellular pathway specifically has been discussed. The cell membrane plays important roles in mediating enzymatic activities as to response and reacts with extracellular environment. Alterations in the calcium signaling pathways in the cell membrane are activated in response to the effects of EMF exposure. Experimental and epidemiological studies have demonstrated that no changes occur in serum prolactin levels in humans following short-term exposure to 900 Mega Hertz (MHz) EMF emitted by mobile phones. The effects of EMF on melatonin and its metabolite, 6-sulfatoxymelatonin, in humans have also been investigated in the clinical studies to show a disturbance in metabolic activity of melatonin. In addition, although 900 MHz EMF effects on NF-κB inflammation, its effects on NF-κB are not clear.: ELF-EMF, extremely low frequency electromagnetic fields; EMF, electromagnetic fields; RF, Radiofrequency; ROS, reactive oxygen species; VGCCs, voltage-gated calcium channels; MAPK, mitogen-activated phosphokinase; NF-κB, nuclear factor kappa B; ERK-1/2, extracellular signal-regulated kinase; GSH-Px, glutathione peroxidase; JNK, Jun N-terminal kinases; SOD, superoxide dismutase; MnSOD, manganese-dependent superoxide dismutase; GLUT1, glucose transporter 1; GSSG-Rd, glutathione reductase MDA malondialdehyde; NO,nitric oxide; LH, luteinizing hormone; FSH, follicle-stimulating hormone.

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PMID: 

Invest Radiol. 1991 Dec ;26(12):1095-100. PMID: 1765445

Abstract Title: 

Glucose homeostasis in rats exposed to magnetic fields.

Abstract: 

The development of diagnostic and therapeutic applications of magnetic fields, especially with regard to magnetic resonance imaging (MRI), draws attention to accompanying possible adverse effects. Recent investigations revealing an increase in insulin release in diabetic rats, increase in glycogen, and decrease in glucose level in rats exposed to magnetic fields, have provided the stimulus for the current studies. Rats were exposed to uniform constant magnetic fields of 10(-3) T and 10(-2) T, 1 hour each day, for a period of ten days. Blood glucose slightly increased, the release of insulin decreased, and the glucagon content increased when compared with controls. The efficiency of the hypophysis-hypothalamic system changed, as indicated by an increase in the level of growth hormone and thyroid-stimulating hormone. The content of the thyroid hormones, triiodothyronine and thyroxine, was higher between the third and seventh day of exposure. An increase in the cortisol level was also observed. The results might implicate a temporarily diabetic-like response in rats exposed to the magnetic field.

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PMID: 

J Biomed Phys Eng. 2016 Mar ;6(1):27-32. Epub 2016 Mar 1. PMID: 27026952

Abstract Title: 

Short-Term Exposure to Electromagnetic Fields Generated by Mobile Phone Jammers Decreases the Fasting Blood Sugar in Adult Male Rats.

Abstract: 

BACKGROUND: Substantial evidence indicates that exposure to electromagnetic fields (EMF) above certain levels can affect human health through triggering some biological responses. According to WHO, short-term exposure to EMF at the levels present in the home/environment do not cause any apparent detrimental effects in healthy individuals. However, now, there is a debate on whether long-term exposure to low level EMF can evoke detrimental biological responses. Although based on the Communications Act of 1934, selling, advertising, using, or importing mobile jammers which block cell phone calls and text messages are illegal acts, in some countries these devices are being used for security purpose and for prevention of cheating during examinations.METHODS: In this study 30 male Wistar rats were randomly divided into 3 groups of 10 each. The control group received no radiation. The sham exposure group was exposed to a switched-off jammer device. After fasting for 12 hours, the exposure group was exposed to EMFs at a distance of 50 cm from the jammer. Blood samples were collected from the tail vein after 24, 48 and72 hours and fasting blood sugar was measured by using a common blood glucose monitor (BIONIME GM110, Taiwan). The significance level was considered 5% and SPSS Ver. 21 was used for statistical analysis. The data were analyzed by ANOVA followed by Tukey's test.RESULTS: A statistically significant difference was observed between blood sugar level in the control and exposure groups after 24, 48 and 72 hours of continuous irradiation (p values were

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PMID: 

Int J Occup Med Environ Health. 2013 Apr ;26(2):235-41. Epub 2013 Jun 15. PMID: 23771861

Abstract Title: 

Effects of exposure to electromagnetic field radiation (EMFR) generated by activated mobile phones on fasting blood glucose.

Abstract: 

OBJECTIVE: Extensive use of mobile phones has been accompanied by a common public debate about possible adverse effects on human health. No study has been published so far to establish any association between the fastest growing innovation of mobile phone and fasting blood glucose. The aim was to determine the effects of exposure to electromagnetic field radiation generated by mobile phones on fasting blood glucose in Wistar Albino rats.MATERIALS AND METHODS: 40 Male Albino rats (Wistar Strain) were divided into 5 equally numerous groups. Group A served as the control one, group B received mobile phone radiation for less than 15 min/day, group C: 15-30 min/day, group D: 31-45 min/day, and group E: 46-60 min/day for a total period of 3 months. Fasting blood glucose was determined by using Spectrophotometer and serum insulin by Enzyme-linked Immunosorbent Assay (ELISA). The Homeostatic Model (HOMA-B) was applied for the assessment ofβ-cell function and (HOMA-IR) for resistance to insulin.RESULTS: Wister Albino rats exposed to mobile phone radiation for longer than 15 min a day for a total period of 3 months had significantly higher fasting blood glucose (p

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PMID: 

Electromagn Biol Med. 2008 ;27(2):135-46. PMID: 18568931

Abstract Title: 

Dirty electricity elevates blood sugar among electrically sensitive diabetics and may explain brittle diabetes.

Abstract: 

Transient electromagnetic fields (dirty electricity), in the kilohertz range on electrical wiring, may be contributing to elevated blood sugar levels among diabetics and pre-diabetics. By closely following plasma glucose levels in four Type 1 and Type 2 diabetics, we find that they responded directly to the amount of dirty electricity in their environment. In an electromagnetically clean environment, Type 1 diabetics require less insulin and Type 2 diabetics have lower levels of plasma glucose. Dirty electricity, generated by electronic equipment and wireless devices, is ubiquitous in the environment. Exercise on a treadmill, which produces dirty electricity, increases plasma glucose. These findings may explain why brittle diabetics have difficulty regulating blood sugar. Based on estimates of people who suffer from symptoms of electrical hypersensitivity (3-35%), as many as 5-60 million diabetics worldwide may be affected. Exposure to electromagnetic pollution in its various forms may account for higher plasma glucose levels and may contribute to the misdiagnosis of diabetes. Reducing exposure to electromagnetic pollution by avoidance or with specially designed GS filters may enable some diabetics to better regulate their blood sugar with less medication and borderline or pre-diabetics to remain non diabetic longer.

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PMID: 

Lancet Planet Health. 2018 12 ;2(12):e512-e514. PMID: 30526934

Abstract Title: 

Planetary electromagnetic pollution: it is time to assess its impact.

Abstract: 

[none]

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PMID: 

Endocrine. 2019 Aug 28. Epub 2019 Aug 28. PMID: 31463884

Abstract Title: 

Vitamin B12 insufficiency is associated with increased risk of gestational diabetes mellitus: a systematic review and meta-analysis.

Abstract: 

PURPOSE: Vitamin B12 deficiency has been associated with a plethora of metabolic abnormalities, such as hyperhomocysteinaemia, insulin resistance and defective synthesis of neurotransmitters and fatty acids. Inconsistency exists as to whether vitamin B12 deficiency is also associated with increased risk of gestational diabetes mellitus (GDM). The purpose of this study was to systematically review and meta-analyze the existing evidence for this association.METHODS: A comprehensive search was conducted in PubMed, Scopus and Cochrane Central up to April 30, 2019. Data are expressed as odds ratio (OR) with 95% confidence interval (CI). The Iindex was employed for heterogeneity.RESULTS: Six studies (n = 1810 pregnant women, 309 GDM cases) fulfilled the eligibility criteria for qualitative and two studies for quantitative analysis. In five studies providing data on vitamin B12 concentrations for both groups, women with GDM had lower vitamin B12 levels when compared with non-GDM women. Women with vitamin B12 deficiency were at higher risk for developing GDM when compared with those who were vitamin B12 sufficient: OR 1.81 (95% CI, 1.25-2.63, I: 0%). Due to the small number of studies, the role of potential confounders could not be safely estimated.CONCLUSIONS: Vitamin B12 deficiency seems to be associated with increased risk of GDM. More studies are needed to further strengthen this finding and to clarify possible pathogenetic mechanisms.

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PMID: 

J Clin Sleep Med. 2019 Aug 14. Epub 2019 Aug 14. PMID: 31482793

Abstract Title: 

Vitamin BDeficiency: A Rare Cause of Excessive Daytime Sleepiness.

Abstract: 

Excessive daytime sleepiness (EDS) is one of the leading reasons that patients present to sleep clinics. Approximately 10% to 14% of the adults report that excessive sleepiness interferes with their daily lives. Common causes of EDS include obstructive sleep apnea, sleep deprivation, circadian rhythm disorders, medication effects, psychiatric conditions especially depression, and primary hypersomnia such as narcolepsy or central idiopathic hypersomnia. Vitamin Bdeficiency is a rare cause of EDS. We are presenting a case of severe vitamin Bdeficiency as an unusual and rare cause of hypersomnia.

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PMID: 

Biomed Res Int. 2018 ;2018:3960408. Epub 2018 May 14. PMID: 29888261

Abstract Title: 

Static Magnetic Fields Modulate the Response of Different Oxidative Stress Markers in a Restraint Stress Model Animal.

Abstract: 

Stress is a state of vulnerable homeostasis that alters the physiological and behavioral responses. Stress induces oxidative damage in several organs including the brain, liver, kidney, stomach, and heart. Preliminary findings suggested that the magnetic stimulation could accelerate the healing processes and has been an effective complementary therapy in different pathologies. However, the mechanism of action of static magnetic fields (SMFs) is not well understood. In this study, we demonstrated the effects of static magnetic fields (0.8 mT) in a restraint stressed animal model, focusing on changes in different markers of oxidative damage. A significant increase in the plasma levels of nitric oxide (NO), malondialdehyde (MDA), and advanced oxidation protein products (AOPP), and a decrease in superoxide dismutase (SOD), glutathione (GSH), and glycation end products (AGEs) were observed in restraint stress model. Exposure to SMFs over 5 days (30, 60, and 240 min/day) caused a decrease in the NO, MDA, AGEs, and AOPP levels; in contrast, the SOD and GSH levels increased. The response to SMFs was time-dependent. Thus, we proposed that exposure to weak-intensity SMFs could offer a complementary therapy by attenuating oxidative stress. Our results provided a new perspective in health studies, particularly in the context of oxidative stress.

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