Seed priming with melatonin improves the seed germination of waxy maize under chilling stress.

PMID:  Sci Rep. 2019 Oct 21 ;9(1):15044. Epub 2019 Oct 21. PMID: 31636312 Abstract Title:  Seed Priming with Melatonin Improves the Seed Germination of Waxy Maize under Chilling Stress via Promoting the Antioxidant System and Starch Metabolism. Abstract:  Chilling stress is one of the major abiotic stresses affecting waxy maize plant growth. Melatonin (MT) is …

This review highlights that melatonin can be an adjuvant therapy and be beneficial in treating patients suffering from colorectal cancer.

PMID:  Biomed Res Int. 2019 ;2019:9740568. Epub 2019 Sep 17. PMID: 31637261 Abstract Title:  Therapeutic Opportunities in Colorectal Cancer: Focus on Melatonin Antioncogenic Action. Abstract:  Colorectal cancer (CRC) influences individual health worldwide with high morbidity and mortality. Melatonin, which shows multiple physiological functions (e.g., circadian rhythm, immune modulation, and antioncogenic action), can be present in …

Molecular and cellular mechanisms of melatonin in osteosarcoma.

PMID:  Cells. 2019 Dec 12 ;8(12). Epub 2019 Dec 12. PMID: 31842295 Abstract Title:  Molecular and Cellular Mechanisms of Melatonin in Osteosarcoma. Abstract:  Osteosarcoma, the most common primary bone malignancy, occurs most frequently in adolescents with a peak of incidence at 11-15 years. Melatonin, an indole amine hormone, shows a wide range of anticancer activities. …

The results of this systematic review indicated that co-administration of melatonin ameliorates the doxorubicin-induced cardiotoxicity.

PMID:  Life Sci. 2019 Dec 13:117173. Epub 2019 Dec 13. PMID: 31843530 Abstract Title:  The role of melatonin on doxorubicin-induced cardiotoxicity: A systematic review. Abstract:  PURPOSE: Doxorubicin, as an effective chemotherapeutic drug, is commonly used for combating various solid and hematological tumors. However, doxorubicin-induced cardiotoxicity is considered as a serious adverse effect, and it limits …

melatonin potentially plays a role in suppression of uterine leiomyoma growth.

PMID:  J Pineal Res. 2020 Jan ;68(1):e12620. Epub 2019 Nov 28. PMID: 31710386 Abstract Title:  Melatonin activates cell death programs for the suppression of uterine leiomyoma cell proliferation. Abstract:  The circadian nature of melatonin has a protective effect on the progression of female reproductive cancers, including breast and ovarian cancers. However, the effect of melatonin …

Melatonin restores the osteoporosis-impaired osteogenic potential of bone marrow mesenchymal stem cells.

PMID:  Free Radic Biol Med. 2019 Oct 24. Epub 2019 Oct 24. PMID: 31669348 Abstract Title:  Melatonin restores the osteoporosis-impaired osteogenic potential of bone marrow mesenchymal stem cells by preserving SIRT1-mediated intracellular antioxidant properties. Abstract:  Postmenopausal osteoporosis (OP) is one of the most common bone diseases that affects millions of aging women. Reduced osteogenesis and …

Melatonin decreases in vitro viability and migration of spheres derived from CF41.Mg canine mammary carcinoma cells.

PMID:  BMC Vet Res. 2019 Nov 4 ;15(1):390. Epub 2019 Nov 4. PMID: 31684950 Abstract Title:  Melatonin decreases in vitro viability and migration of spheres derived from CF41.Mg canine mammary carcinoma cells. Abstract:  BACKGROUND: Mammary cancer is a common disease affecting female dogs, where approximately 50% of the cases are malignant. There is a subpopulation …

Melatonin ameliorates cerebral ischemia/reperfusion injury through SIRT3 activation.

PMID:  Life Sci. 2019 Dec 15 ;239:117036. Epub 2019 Nov 4. PMID: 31697951 Abstract Title:  Melatonin ameliorates cerebral ischemia/reperfusion injury through SIRT3 activation. Abstract:  AIMS: Previous literature has shown that melatonin plays a critical role in protecting against cerebral ischemia/reperfusion (I/R) injury. Sirtuin3(SIRT3), as one member of the sirtuin family, protects against oxidative stress-related diseases. …

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