PMID: Vaccine. 2010 Sep 14 ;28(40):6609-12. Epub 2010 Jul 30. PMID: 20674876 Abstract Title: Severe combined immunodeficiency (SCID) and rotavirus vaccination: reports to the Vaccine Adverse Events Reporting System (VAERS). Abstract: BACKGROUND: Rotavirus vaccines are the only live vaccines recommended for infants in the US. Postmarketing reports have described severe gastroenteritis with vaccine viral shedding …
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This review describes incidences of vaccine shedding following the rotavirus vaccine.
PMID: Expert Rev Vaccines. 2012 Nov ;11(11):1311-4. PMID: 23249230 Abstract Title: Rotavirus vaccine-derived shedding and viral reassortants. Abstract: EVALUATION OF: Donato CM, Ch’ng LS, Boniface KF et al. Identification of strains of RotaTeq rotavirus vaccine in infants with gastroenteritis following routine vaccination. J. Infect. Dis. 206(3), 377–383 (2012).Two live, attenuated rotavirus vaccines, RotaTeq(®) (Merck) and …
The findings of this study demonstrate that premature infants have rotavirus-positive stools by EIA, viral culture, and RT-PCR at varying time points during 2 weeks following first-dose immunization with RV5.
PMID: Vaccine. 2011 Oct 19 ;29(45):8141-6. Epub 2011 Aug 19. PMID: 21856359 Abstract Title: Rotavirus shedding in premature infants following first immunization. Abstract: OBJECTIVE: There is limited data regarding rotavirus vaccine shedding in premature infants. We describe the natural history of rotavirus shedding in premature infants in the 2-week period following first immunization with RotaTeq(®), …
160 intussusception and 11 Kawasaki disease adverse event reports were identified in VAERS when RotaTeq was administered or co-administered with other vaccines.
PMID: Med Sci Monit. 2008 Mar ;14(3):PH9-16. PMID: 18301365 Abstract Title: RotaTeq vaccine adverse events and policy considerations. Abstract: BACKGROUND: Rotavirus is the leading cause of severe gastroenteritis in children read more
Findings of this meta-analysis suggest that the rotavirus vaccine is associated with an increased risk on the development of intussusception, principally seen after administration of the first dose of vaccine.
PMID: Vaccine. 2017 07 24 ;35(33):4276-4286. Epub 2017 Jun 22. PMID: 28648544 Abstract Title: Risk of intussusception following rotavirus vaccination: An evidence based meta-analysis of cohort and case-control studies. Abstract: BACKGROUND: International post-licensure studies on rotavirus vaccines have identified an increased risk of intussusception in infants after administration. The first developed rotavirus vaccine (Rotashield (RRV-TV)) …
A case report of post-rotavirus vaccine intussusception, rectal bleeding, and abdominal pain.
PMID: Case Rep Pediatr. 2017 ;2017:9461315. Epub 2017 Jan 9. PMID: 28163948 Abstract Title: Rectal Bleeding and Abdominal Pain Following Vaccination in a 4-Month-Old Infant. Abstract: Intussusception is one of the most frequent causes of intestinal obstruction in infants. Rotavirus vaccination has been associated with intussusception in the medical literature. We report a case of …
A case report of post-rotavirus intussusception in identical twins.
PMID: Hum Vaccin Immunother. 2016 Sep ;12(9):2419-21. Epub 2016 Apr 12. PMID: 27070956 Abstract Title: Post-rotavirus vaccine intussusception in identical twins: A case report. Abstract: The intussusception is one of the most frequent causes of occlusive syndrome in infants and in children. (1) The mesenteric lymphadenopathy, wich is very rare post rotavirus vaccination, can cause …
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A case report of a 10-month-old experiencing purpura and acute gastrointestinal bleeding following MMR vaccination.
PMID: Southeast Asian J Trop Med Public Health. 2014 Sep ;45(5):1053-7. PMID: 25417506 Abstract Title: Measles-mumps-rubella vaccination induced thrombocytopenia: a case report and review of the literature. Abstract: Immune thrombocytopenia (ITP) is a disease with autoimmune destruction of platelets. ITP among children has been associated with viral infections and some vaccinations. We report a case …
14% of stools obtained during post-vaccination diarrheal episodes were rotavirus-positive, some being vaccine strain-positive.
PMID: J Infect Dis. 2003 Mar 1 ;187(5):791-800. Epub 2003 Feb 24. PMID: 12599053 Abstract Title: Horizontal transmission of rhesus monkey rotavirus-based quadrivalent vaccine during a phase 3 clinical trial in Caracas, Venezuela. Abstract: During a phase 3 clinical trial of rhesus monkey rotavirus-based quadrivalent vaccine in Venezuela, 2207 infants received 3 oral doses of …
Fecal shedding of rotavirus vaccine virus after the first dose of RV5 occurred over a wide range of post-vaccination days not previously studied.
PMID: Vaccine. 2011 May 31 ;29(24):4151-5. Epub 2011 Apr 6. PMID: 21477676 Abstract Title: Detection of fecal shedding of rotavirus vaccine in infants following their first dose of pentavalent rotavirus vaccine. Abstract: Studies on rotavirus vaccine shedding and its potential transmission within households including immunocompromised individuals are needed to better define the potential risks and …