Procyanidins extracted from lotus seedpod ameliorate amyloid-β-induced toxicity in rat pheochromocytoma cells.

PMID:  Oxid Med Cell Longev. 2018 ;2018:4572893. Epub 2018 Oct 28. PMID: 30538801 Abstract Title:  Procyanidins Extracted from Lotus Seedpod Ameliorate Amyloid–Induced Toxicity in Rat Pheochromocytoma Cells. Abstract:  Alzheimer's disease (AD) is a progressive neurodegenerative disease, which is characterized by extracellular senile plaque deposits, intracellular neurofibrillary tangles, and neuronal apoptosis. Amyloid-(A) plays a critical role …

Lotus seedpod proanthocyanidins protect against neurotoxicity after methyl-mercuric chloride injury.

PMID:  Ecotoxicol Environ Saf. 2019 Nov 15 ;183:109560. Epub 2019 Aug 14. PMID: 31421536 Abstract Title:  Lotus seedpod proanthocyanidins protect against neurotoxicity after methyl-mercuric chloride injury. Abstract:  In the present study, to investigate the prevention mechanism of proanthocyanidins from lotus seedpod (LSPCs) on methyl mercuric chloride (MMC) induced neurotoxicity, neuron/astrocyte cells were co-cultured to simulate …

Lotus seedpod extracts reduced lipid accumulation and lipotoxicity in hepatocytes.

PMID:  Nutrients. 2019 Nov 28 ;11(12). Epub 2019 Nov 28. PMID: 31795130 Abstract Title:  Lotus Seedpod Extracts Reduced Lipid Accumulation and Lipotoxicity in Hepatocytes. Abstract:  Non-alcoholic fatty liver disease (NAFLD) is closely associated with metabolic disorders, including hepatic lipid accumulation and lipotoxicity. Plant-derived polyphenols have attracted considerable attention in the prevention of NAFLD. Lotus seedpod, …

M. oleifera and its isolated compounds potentially have an anti-allergic activity by inhibiting both early and late phases of allergic reactions.

PMID:  BMC Complement Altern Med. 2019 Dec 11 ;19(1):361. Epub 2019 Dec 11. PMID: 31829185 Abstract Title:  In vitro anti-allergic activity of Moringa oleifera Lam. extracts and their isolated compounds. Abstract:  BACKGROUND: Moringa oleifera Lam. is a commonly used plant in herbal medicine and has various reported bioactivities such as antioxidant, antimicrobial, anticancer and antidiabetes. …

Allicin modulates diclofenac sodium induced hepatonephro toxicity.

PMID:  Environ Toxicol Pharmacol. 2019 Nov 23 ;74:103306. Epub 2019 Nov 23. PMID: 31812117 Abstract Title:  Allicin modulates diclofenac sodium induced hepatonephro toxicity in rats via reducing oxidative stress and caspase 3 protein expression. Abstract:  PURPOSE: This study was designed to evaluate the protective effects of allicin against diclofenac sodium induced hepatonephro toxicity in rats.METHODS: …

Allicin improves metabolism in high-fat diet-induced obese mice by modulating the gut microbiota.

PMID:  Nutrients. 2019 Dec 2 ;11(12). Epub 2019 Dec 2. PMID: 31810206 Abstract Title:  Allicin Improves Metabolism in High-Fat Diet-Induced Obese Mice by Modulating the Gut Microbiota. Abstract:  Allicin, naturally present in the bulbs of the lily family, has anticancer, blood pressure lowering, blood fat lowering and diabetes improving effects. Recent studies have shown that …

These results suggested that grape seed proanthocyanidins might be promising phytochemicals against liver cancer.

PMID:  Nutrients. 2019 Dec 6 ;11(12). Epub 2019 Dec 6. PMID: 31817589 Abstract Title:  Grape Seed Proanthocyanidins Induce Autophagy and Modulate Survivin in HepG2 Cells and Inhibit Xenograft Tumor Growth in Vivo. Abstract:  Liver cancer is one of the leading causes of death worldwide. Although radiotherapy and chemotherapy are effective in general, they present various …

Melatonin plus folic acid treatment ameliorates reserpine-induced fibromyalgia.

PMID:  Antioxidants (Basel). 2019 Dec 6 ;8(12). Epub 2019 Dec 6. PMID: 31817734 Abstract Title:  Melatonin Plus Folic Acid Treatment Ameliorates Reserpine-Induced Fibromyalgia: An Evaluation of Pain, Oxidative Stress, and Inflammation. Abstract:  BACKGROUND: Fibromyalgia is a chronic condition characterized by increased sensory perception of pain, neuropathic/neurodegenerative modifications, oxidative, and nitrosative stress. An appropriate therapy is …

Cocoa ameliorates renal injury in Zucker diabetic fatty rats by preventing oxidative stress, apoptosis and inactivation of autophagy.

PMID:  Food Funct. 2019 Dec 11 ;10(12):7926-7939. PMID: 31773121 Abstract Title:  Cocoa ameliorates renal injury in Zucker diabetic fatty rats by preventing oxidative stress, apoptosis and inactivation of autophagy. Abstract:  Redox balance, autophagy and apoptosis are main processes involved in the development of diabetic nephropathy. Epidemiological and animal studies suggest that cocoa might reduce the …

Supplementation of magnesium and choline is more effective than either magnesium or choline alone to improve coagulation in subjects with T2DM.

PMID:  Biol Trace Elem Res. 2019 Aug 5. Epub 2019 Aug 5. PMID: 31385202 Abstract Title:  Effects of Choline and Magnesium Concurrent Supplementation on Coagulation and Lipid Profile in Patients with Type 2 Diabetes Mellitus: a Pilot Clinical Trial. Abstract:  Metabolic failure is associated with dyslipidemia and coagulation which can result in a higher risk …

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