Vitamin C may thus have a potential role in the prevention and treatment of TNBC metastasis.

PMID:  Nutrients. 2019 Dec 6 ;11(12). Epub 2019 Dec 6. PMID: 31817810 Abstract Title:  Vitamin C Inhibits Triple-Negative Breast Cancer Metastasis by Affecting the Expression of YAP1 and Synaptopodin 2. Abstract:  Vitamin C supplementation has been shown to decrease triple-negative breast cancer (TNBC) metastasis. However, the molecular mechanism whereby vitamin C inhibits metastasis remains elusive. …

Protective effects on 60Co-γ radiation damage of pine cone polyphenols from Pinus koraiensis-loaded chitosan microspheres in vivo.

PMID:  Molecules. 2018 06 8 ;23(6). Epub 2018 Jun 8. PMID: 29890658 Abstract Title:  Protective Effects on 60Co-γ Radiation Damage of Pine Cone Polyphenols from-Loaded Chitosan Microspheres In Vivo. Abstract:  A novel chitosan microsphere for encapsulating pine cone polyphenols (PP) fromwas successfully prepared using an emulsion crosslinking technique. The characteristics of pine polyphenol-loaded microspheres (PPM) …

Physicochemical properties, bioaccessibility and antioxidant activity of the polyphenols from pine cones of Pinus koraiensis.

PMID:  Int J Biol Macromol. 2019 Apr 1 ;126:385-391. Epub 2018 Dec 18. PMID: 30576738 Abstract Title:  Physicochemical properties, bioaccessibility and antioxidant activity of the polyphenols from pine cones of Pinus koraiensis. Abstract:  This study investigated the physicochemical properties, bioaccessibility and in vitro antioxidant ability of the polyphenols isolated from the pine cones of Pinus …

Phloretin loaded chitosan nanoparticles augments the pH-dependent mitochondrial-mediated intrinsic apoptosis in human oral cancer cells.

PMID:  Int J Biol Macromol. 2019 Jun 1 ;130:997-1008. Epub 2019 Mar 5. PMID: 30844461 Abstract Title:  Phloretin loaded chitosan nanoparticles augments the pH-dependent mitochondrial-mediated intrinsic apoptosis in human oral cancer cells. Abstract:  The aim of the present investigation is to explore the innovative platform for the synthesis of plant-based nanoparticles, which contain biocompatible and …

A systemic review of the pharmacological aspects and potential use of phloretin.

PMID:  Mini Rev Med Chem. 2019 ;19(13):1060-1067. PMID: 30864525 Abstract Title:  Pharmacological Aspects and Potential Use of Phloretin: A Systemic Review. Abstract:  Over the past two decades, many researchers have concluded that a diet rich in polyphenolic compounds plays an important therapeutic role in reducing the risk of cancer, cardiovascular disease, inflammation, diabetes, and other …

These studies suggest ginger and 6-shogaol have the potential to combat asthma.

PMID:  Am J Physiol Lung Cell Mol Physiol. 2019 Dec 4. Epub 2019 Dec 4. PMID: 31800263 Abstract Title:  Ginger and its Bioactive Component 6-Shogaol Mitigate Lung Inflammation in a Murine Asthma Model. Abstract:  Asthma, a common disorder associated with airway inflammation and hyperresponsiveness, remains a significant clinical burden in need of novel therapeutic strategies. …

Western diet-induced fear memory impairment is attenuated by 6-shogaol in C57BL/6N mice.

PMID:  Behav Brain Res. 2019 Dec 6:112419. Epub 2019 Dec 6. PMID: 31816337 Abstract Title:  Western diet-induced fear memory impairment is attenuated by 6-shogaol in C57BL/6N mice. Abstract:  Dementia is a progressive cognitive diminution impeding with normal daily activities that is constantly on the increase. Currently, the estimated prevalence is 50 million affected people worldwide, …

A case report of a confirmed vaccine-related polioencephalomyelitis.

PMID:  Scott Med J. 1988 Aug ;33(4):306-7. PMID: 2847313 Abstract Title:  Vaccine-induced polioencephalomyelitis in Scotland. Abstract:  A six-month-old British female, living in Glasgow was admitted in June 1986 with a four-day history of fever and lower limb weakness following immunisation with oral polio and triple (DTP) vaccines. Examination revealed paralysis of all limbs, facial muscles …

Oral polio vaccinees can continue to shed for at least 13 weeks.

PMID:  J Clin Microbiol. 2011 May ;49(5):1777-83. Epub 2011 Mar 16. PMID: 21411577 Abstract Title:  Use of a novel real-time PCR assay to detect oral polio vaccine shedding and reversion in stool and sewage samples after a mexican national immunization day. Abstract:  During replication, oral polio vaccine (OPV) can revert to neurovirulence and cause paralytic …

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